Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings submission deadline 31 Aug 2025 | 4 articles | Viewed by 8830 | Submission Open
Keywords: cryotherapy; local cryotherapy; cryostimulation; partial/local/whole-body cryostimulation; par-tial/local/whole-body cryotherapy; personalized rehabilitation; multidisciplinary rehabilitation; cold therapy; cold exposure; adjuvant therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Challenges and Advances in Orthopaedic and Trauma Surgery submission deadline 31 Aug 2025 | 4 articles | Viewed by 7689 | Submission Open
Keywords: orthopaedic surgery; traumatology; musculoskeletal disorders; innovation in orthopaedics; individualised treatment; post-operative rehabilitation; clinical research
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Otolaryngology: Special Topic Otology—2nd Edition submission deadline 31 Aug 2025 | 3 articles | Viewed by 6137 | Submission Open
Keywords: cochlear implants in children; adults; and older adults; active middle-ear implants in children; adults; and the elderly; new indications in otology; active transcutaneous bone conduction implants in children; adults; and the elderly; hearing loss and cholesteatoma; implantable and non-implantable solutions for malformations; age-related hearing loss; single-sided deafness; cochlear implantation; otitis media; tinnitus; quality of life; burden of hearing loss; genetics and epigenetics of hearing loss; robotic surgery; novel biomarkers for the diagnosis and prognosis of hearing loss; novel intra-operative objective measures for hearing implants; alternative treatment options to implantable devices; MRI
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Advances in Traumatic Brain Injury and Concussion
edited by Spencer W. Liebel
submission deadline 31 Aug 2025 | 1 articles | Viewed by 3936 | Submission Open
Keywords: traumatic brain injury; concussion; personalized medicine; neuroimaging; cognitive functioning; depression; connectomics; brain injury treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Diagnosis and Personalized Treatments of Chronic Kidney Diseases submission deadline 31 Aug 2025 | 2 articles | Viewed by 3122 | Submission Open
Keywords: biomarkers for early diagnosis; genetic testing; precision medicine approaches; novel therapies; telemedicine and remote monitoring; nutritional interventions; regenerative medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Biomedical Tools in Diagnosis and Personalized Therapy of Cardiovascular Disease
edited by Nikolaos Koumallos and Konstantinos A. Aznaouridis
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2916 | Submission Open
Keywords: cardiovascular disease; diagnosis; personalized therapy; biomedical tools; cardiovascular imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Updates on Personalized Upper Gastrointestinal Endoscopy submission deadline 31 Aug 2025 | 2 articles | Viewed by 2642 | Submission Open
Keywords: operative endoscopy; post-surgical complications; achalasia; Zenker diverticulum; GERD; gastroparesis
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Chronic Kidney Disease: Diagnostics, Treatment, and Outcomes
edited by
submission deadline 31 Aug 2025 | Viewed by 198 | Submission Open
Keywords: chronic kidney disease; clinical research; basic research; epidemiology; prevention; public awareness; diagnostics; treatment; outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Pathology and Molecular Diagnostics in the Personalized Treatment of Lung Diseases submission deadline 5 Sep 2025 | 6 articles | Viewed by 7865 | Submission Open
Keywords: lung; tumor; biomarkers; interstitial lung diseases; molecular; infections
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in the ICU—2nd Edition submission deadline 10 Sep 2025 | 1 articles | Viewed by 2021 | Submission Open
Keywords: ARDS; mechanical ventilation; respiratory mechanics; monitoring; ultrasonography; respiratory muscles; diaphragm; cardiomyopathy; arrhythmias; sepsis; blood stream infections; antimicrobial resistance; ventilator-associated pneumonia; neuromonitoring; MODS; COVID-19
(This special issue belongs to the Section Personalized Critical Care)
New Advances in Techniques and Personalized Medicine in Cardiology
edited by
submission deadline 10 Sep 2025 | 1 articles | Viewed by 1213 | Submission Open
Keywords: cardiovascular precision therapy; cardiovascular pharmacological therapy; pharmacogenetics; cardio-imaging; epigenetics; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Colorectal Cancers: Clinical and Therapeutical Updates and Challenges
edited by , and Adrian Constantin
submission deadline 10 Sep 2025 | Viewed by 460 | Submission Open
Keywords: colorectal cancer; clinical research; translational research; cancer biomarker; targeted therapy; medical imaging; colorectal surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Treatment of Oligometastatic Disease
edited by
submission deadline 15 Sep 2025 | Viewed by 427 | Submission Open
Keywords: oligometastatic disease; oligorecurrence; oligoprogression; oligoconsolidation; metastasectomy; stereotactic body radiotherapy (SBRT); novel systemic agents; target therapies; chemotherapy; immunotherapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Sep 2025 | 2 articles | Viewed by 3785 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances of Precision Medicine in Oncology submission deadline 25 Sep 2025 | 2 articles | Viewed by 6810 | Submission Open
Keywords: precision medicine; personalized cancer care; circulating tumor cells; biomolecules; liquid biopsies; omics technologies; biomarkers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Cutting-Edge Diagnostics: The Impact of Imaging on Precision Medicine
edited by
submission deadline 25 Sep 2025 | 2 articles | Viewed by 3357 | Submission Open
Keywords: advanced imaging techniques; AI-enhanced imaging; molecular imaging; imaging biomarkers; precision medicine; personalized diagnostics; early disease detection; imaging data integration; genomics and imaging; imaging-guided interventions; clinical imaging applications; comparative imaging effectiveness; innovative imaging technologies; medical imaging advances; diagnostic accuracy; patient-specific imaging; functional imaging; quantitative imaging; radiomics; theranostics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Updates on Arrhythmia and Cardiac Electrophysiology submission deadline 25 Sep 2025 | 1 articles | Viewed by 1918 | Submission Open
Keywords: ablation energy mode; conduction system pacing; pulsed field ablation; leadless pacing; resynchronization; myocardial work; atrial fibrillation
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
The Applications of Non-Invasive Brain Stimulation in Neuropsychiatric Research and Treatment submission deadline 25 Sep 2025 | 1 articles | Viewed by 1818 | Submission Open
Keywords: neuroscience; non-invasive brain stimulation; rehabilitation; neuropsychiatric; neurophysiology; neuropsychology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Pathological Diagnosis submission deadline 25 Sep 2025 | 1 articles | Viewed by 610 | Submission Open
Keywords: personalized medicine; pathology; pathological; trauma; toxicology; informed consent
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Interventional Radiology in Oncology
edited by
submission deadline 25 Sep 2025 | Viewed by 369 | Submission Open
Keywords: artificial intelligence; oncological imaging; hybrid imaging; endovascular radiology; percutaneous procedures; radiomics; MRI; CT; PET/CT; photon-counting CT; cone-beam CT
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Pathological Mechanism of Breast Cancer
edited by
submission deadline 25 Sep 2025 | Viewed by 353 | Submission Open
Keywords: breast cancer; metastatic breast cancer; biomarkers; molecular profiling; immune landscape; genomics; personalized treatment; targeted therapy
(This special issue belongs to the Section Mechanisms of Diseases)
Orthopedic Diseases: Advances in Limb Reconstruction
edited by Taylor J. Reif and Jason Shih Hoellwarth
submission deadline 25 Sep 2025 | 1 articles | Viewed by 218 | Submission Open
Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Neuroimaging Biomarkers for Precision Medicine in Neuropsychiatry: A Multidisciplinary Update
edited by
submission deadline 25 Sep 2025 | Viewed by 161 | Submission Open
Keywords: neuroimaging; neuropsychiatry; psychiatry; psychology; neuroscience; biomarkers; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Neuro-Imaging: Advances and Challenges
edited by Onur Tanglay
submission deadline 25 Sep 2025 | Viewed by 112 | Submission Open
Keywords: neuroimaging; precision medicine; biomarkers; brain health; neurotechnology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
How to Undertake Personalized Assessments and Cures for Pain
edited by Barbara Rocca and
submission deadline 30 Sep 2025 | 6 articles | Viewed by 12487 | Submission Open
Keywords: pain; suffering; personalization; evaluation; treatment; outcome; medicine; surgery; rehabilitation; psychology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Head and Neck Oncologic Surgery: Clinical Updates and New Perspectives in Precision Medicine Era
edited by Filippo Carta and Roberto Puxeddu
submission deadline 30 Sep 2025 | 3 articles | Viewed by 7494 | Submission Open
Keywords: head and neck cancer; squamous cell carcinoma; free flap; microsurgery; oral cancer; laryngeal cancer; pharyngeal cancer; skin cancer; salivary gland cancer; precision medicine; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
United Airway Disease: Current Perspectives submission deadline 30 Sep 2025 | 1 articles | Viewed by 3741 | Submission Open
Keywords: chronic rhinosinusitis; asthma; personalized medicine; type-2 inflammation; united airway; obstructive sleep apnoea; monoclonal antibodies; endotype; rhinology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Treatment of Neurological Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 3050 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; dementia; epilepsy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1778 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Infectious Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 1753 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response; potential adverse events; and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 30 Sep 2025 | 1 articles | Viewed by 725 | Submission Open
Keywords: prenatal diagnosis; maternal– fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
edited by Eyal Yaacobi
submission deadline 30 Sep 2025 | 1 articles | Viewed by 466 | Submission Open
Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Progress in Prevention and Personalized Treatment for Cardiovascular Diseases submission deadline 30 Sep 2025 | Viewed by 392 | Submission Open
Keywords: vascular medicine; hypertension; heart failure; multimorbidity; lifestyle changes; venous thromboembolic disease (VTE); cardiovascular risk; chronic coronary artery disease; cardiovascular therapy; atherosclerosis; systemic inflammation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Advances in Neurooncology and Personalized Neurosurgery
edited by Csaba Zsolt Oláh and László Sipos
submission deadline 30 Sep 2025 | Viewed by 131 | Submission Open
Keywords: neuro-oncology; brain surgery; spine surgery; surgical techniques; quality of life; patient outcomes; interdisciplinary treatment; artificial intelligence; cutting-edge oncological treatments; radiotherapy; radiosurgery; microbiome aneurysm; perimesencephalic subarachnoid hemorrhage; COVID; microbiome; brain abscess; bacterium; fungi
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Reproduction and Fertility
edited by Nikos K. Nikolettos
submission deadline 10 Oct 2025 | Viewed by 210 | Submission Open
Keywords: personalized medicine; fertility; assisted reproduction; reproductive health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Metabolism Disorders
edited by Mehrnaz Abbasi
submission deadline 10 Oct 2025 | Viewed by 122 | Submission Open
Keywords: metabolic syndrome; obesity; insulin resistance; hypertension; type 2 diabetes; energy metabolism; fatty acid oxida-tion; gut microbiota; brown adipose tissue (BAT); white adipose tissue (WAT); nutritional interventions; lifestyle modifications; pharmacological treatments; phytochemicals; vitamins and supplements; public health; epidemiology of obesity; preventive strategies; genetic factors; metabolic health research; adipose tissue function
(This special issue belongs to the Section Mechanisms of Diseases)
Exploiting Metabolic Weaknesses: A Novel Approach to Overcome Drug Resistance in Cancer Therapy
edited by
submission deadline 15 Oct 2025 | 1 articles | Viewed by 2574 | Submission Open
Keywords: drug resistance; tumor metabolism; immunometabolism; metabolomics; metabolites; precision medicine
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Dermatology: Molecular Mechanisms, Diagnosis and Therapeutic Targets submission deadline 15 Oct 2025 | 2 articles | Viewed by 2430 | Submission Open
Keywords: dermatologic diseases; atopic dermatitis; psoriasis; hidradenitis suppurativa; vitiligo; alopecia; melanoma; scleroderma
(This special issue belongs to the Section Molecular Targeted Therapy)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 15 Oct 2025 | 1 articles | Viewed by 682 | Submission Open
Keywords: artificial intelligence  ; personalized medicine  ; predictive modeling  ; genomics  ; proteomics  ; AI-driven diagnostics  ; patient-specific treatment  ; drug discovery  ; healthcare innovation  ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Multiple Biomarkers for the Diagnosis and Precision Treatment of Depression
edited by
submission deadline 15 Oct 2025 | Viewed by 417 | Submission Open
Keywords: depression; biomarkers; inflammation; autoimmunity; genomics; physiology; radiography
(This special issue belongs to the Section Disease Biomarker)
Gestational Diabetes: Challenges and Cutting-Edge Research submission deadline 15 Oct 2025 | Viewed by 135 | Submission Open
Keywords: gestational diabetes; continuous glucose monitor; fetal health; pregnancy; macrosomia; personalized management
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Otolaryngology: Novel Prognostic Markers
edited by and Wolf-Dieter Baumgartner
submission deadline 20 Oct 2025 | 5 articles | Viewed by 8220 | Submission Open
Keywords: personalized medicine; otorhinolaryngology; otology; head and neck surgery; prognostic markers; individualized treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Hearing Disorder: Diagnosis, Implantation and Latest Research submission deadline 20 Oct 2025 | 1 articles | Viewed by 3717 | Submission Open
Keywords: hearing loss; cochlear implants; hearing preservation; neuroplasticity; outcomes in cochlear implantation; prosthesis fitting; bone-anchored hearing aids; speech perception; sound localization; gene therapy; inner-ear cell regeneration; vestibular disorders; telemedicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Hepato-Pancreatic-Biliary Surgery: New Perspectives in Precision Medicine Era
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 1027 | Submission Open
Keywords: hepato-pancreatic– biliary surgery; precision medicine; genomics; proteomics; nanotechnologies; molecular pathways; artificial intelligence; predictive modeling
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Cancer Biology and Precision Oncology
edited by Wen-Shin Chang
submission deadline 20 Oct 2025 | Viewed by 167 | Submission Open
Keywords: biomarkers; cancer genomics; diagnosis; single nucleotide polymorphism (SNP); prognosis
(This special issue belongs to the Section Disease Biomarker)
State of the Art in Cardiac Imaging
edited by
submission deadline 25 Oct 2025 | 1 articles | Viewed by 1631 | Submission Open
Keywords: cardiology; imaging; scintigraphy; SPECT; PET; computed tomography; magnetic resonance; echocardiography; heart failure; coronary artery disease
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Interventional Cardiology: Latest Technology, Progress and Challenge
edited by Grzegorz Sobieszek and Maksymilian P. Opolski
submission deadline 25 Oct 2025 | Viewed by 520 | Submission Open
Keywords: interventional cardiology; chronic total occlusions (CTO); complex and high-risk coronary interventions (CHIP); intravascular lithotripsy (IVL); structural heart interventions; heart failure interventional treatment; electrotherapy; right- and left-ventricle hemodynamic support; left-ventricle assist device (LVAD)
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Recent Innovations and Artificial Intelligence in Interventional Radiology: A Step Towards Personalized Medicine
edited by , Giuseppe Pellegrino and Salvatore Alessio Angileri
submission deadline 25 Oct 2025 | Viewed by 161 | Submission Open
Keywords: interventional radiology; artificial intelligence; augmented reality
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Therapeutic Strategies and Future Perspectives for Infectious Diseases
edited by Duduzile Ndwandwe
submission deadline 25 Oct 2025 | Viewed by 99 | Submission Open
Keywords: infectious diseases; antimicrobial resistance; therapeutic strategies; pandemic preparedness; innovative treatments; personalized medicine; artificial intelligence in health; global health equity
(This special issue belongs to the Section Epidemiology)
State of the Art in Pathogenesis and Targeted Therapy in Chronic Obstructive Pulmonary Disease
edited by Emanuela Tudorache
submission deadline 30 Oct 2025 | Viewed by 73 | Submission Open
Keywords: COPD; effective treatments; molecular; genetic; inflammation; biomarkers for diagnosis and prognosis; personalized medicine; novel drug delivery systems; patient outcomes; clinical practice
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
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