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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Medicine in Epidemiology and Infectious Diseases

edited by Takalani Grace Tshitangano and Daniel Ter Goon

submission deadline 20 Sep 2026 | Viewed by 439 | Submission Open

Keywords: personalized medicine; infectious disease; epidemiology; precision public health; pharmacogenomics; AI in epidemiology; pathogen genomics; digital health; risk prediction models; multi-omics integration; machine learning; personalized treatment

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

Laparoscopy, Perioperative Care and Complications in Surgery for Gastrointestinal Diseases

edited by Michał Kisielewski

submission deadline 25 Sep 2026 | 3 articles | Viewed by 13528 | Submission Open

Keywords: laparoscopy; perioperative care; colorectal surgery; minimally invasive surgery; upper digestive surgery; hepatobiliary surgery; postoperative complications

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives

edited by Roberta Carbonara and

Alba Fiorentino

submission deadline 25 Sep 2026 | 4 articles | Viewed by 7658 | Submission Open

Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Artificial Intelligence in Cardiovascular Diseases: Toward Personalized Diagnosis and Treatment

edited by Diaa A. Hakim

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1164 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; cardiovascular diseases; personalized treatment

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

Clinical Management and Personalized Treatment in Digestive Surgery

edited by

Bogdan Severus Gaspar

submission deadline 25 Sep 2026 | Viewed by 720 | Submission Open

Keywords: digestive disease; digestive cancers; gastrointestinal surgery; stomach; pancreas; liver

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Reproduction and Fertility

edited by Nikos K. Nikolettos

submission deadline 25 Sep 2026 | Viewed by 684 | Submission Open

Keywords: personalized medicine; fertility; assisted reproduction; reproductive health

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Psychiatry: Clinical Research and Personalized Medicine

edited by

Georgios Floros

submission deadline 25 Sep 2026 | Viewed by 430 | Submission Open

Keywords: personalized therapy; clinical psychiatry; pharmacogenomics; biomarker-driven therapies; machine learning; digital phenotyping; precision psychiatry; mental health; individualized treatment; neuroimaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Head and Neck Disease: Personalized Approaches to Screening and Diagnosis

edited by Heejin Kim

submission deadline 25 Sep 2026 | Viewed by 319 | Submission Open

Keywords: otolaryngology; head and neck; rhinosinusitis; thyroidectomy; tonsillectomy; personalized; screening; diagnosis

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

New Insights into Personalized Medicine for Anesthesia and Pain

edited by

Hyun Kang

and Guen Joo Choi

submission deadline 30 Sep 2026 | 8 articles | Viewed by 13065 | Submission Open

Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain

(This special issue belongs to the Section Personalized Medical Care)

Novel Challenges and Therapeutic Options for Digestive and Liver Diseases—2nd Edition

edited by

Daniel Paramythiotis

and

Eleni Karlafti

submission deadline 30 Sep 2026 | 3 articles | Viewed by 8414 | Submission Open

Keywords: digestive disease; gastrointestinal disease; pancreas; gallbladder; liver disease; therapy; management; microbiota; drugs; diagnosis

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Innovations in Airway Diseases

edited by

Ourania S. Kotsiou

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4570 | Submission Open

Keywords: airway pathophysiology; respiratory therapeutics; novel diagnostic techniques; personalized medicine; clinical trials in airway diseases; innovative treatment strategies; molecular mechanisms; biotechnological advances; environmental impacts; advanced diagnostic tools

(This special issue belongs to the Section Mechanisms of Diseases)

Novel Challenges and Advances in Neuro-Oncology

edited by

Keyoumars Ashkan

and José Pedro Lavrador

submission deadline 30 Sep 2026 | 3 articles | Viewed by 3732 | Submission Open

Keywords: neuro-oncology; brain mapping; personalized surgical resections; radiotherapy; proton therapy; chemotherapy; immunotherapy; tumour-brain interaction; flourescence-guided surgery; intraoperative treatments; postoperative rehabilitation; engenieering and neuro-oncology

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Developments in Cancer Biomarkers for Diagnosis and Prognosis

edited by

Raghu Sinha

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2837 | Submission Open

Keywords: cancer biomarkers; diagnosis; prognosis; therapy response biomarkers; miRNA, RNA, DNA, and proteins; cell-free biomarkers; saliva, serum, and plasma; inflammation; metabolites

(This special issue belongs to the Section Disease Biomarkers)

Current Status and Future Prospects of Histopathology in Cancer Diagnosis

edited by Serena Ammendola and

Valeria Barresi

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2387 | Submission Open

Keywords: histopathology; cancer diagnostics; cancer biology; prognostic markers; targeted therapy; immunohistochemistry; molecular biology; digital pathology; artificial intelligence

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Neuropsychology

edited by

Bruno Peixoto

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2003 | Submission Open

Keywords: precision neuroscience; advances in neuropsychology; neurocognitive profiling; neurorehabilitation; personalized medicine; biomarkers

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Approaches in Cardiothoracic Surgery

edited by

Kyriakos Spiliopoulos

and

Dimos E. Karangelis

submission deadline 30 Sep 2026 | Viewed by 391 | Submission Open

Keywords: minimal invasive cardiothoracic surgery; complex cardiothoracic procedures; redo surgery; robotic cardiothoracic surgery; AI in the treatment of cardiothoracic diseases; guidelines of the treatment of cardiothoracic diseases; education and training in cardiothoracic surgery; perioperative management; technical advancements, innovations, research

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience

edited by

Andres M. Alvarez-Pinzon

submission deadline 15 Oct 2026 | 1 articles | Viewed by 18309 | Submission Open

Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine

edited by Jerome Rene Lechien

submission deadline 15 Oct 2026 | 10 articles | Viewed by 14292 | Submission Open

Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Advances in Bariatric Surgery

edited by

Maria Sofia

and Andrea Peri

submission deadline 15 Oct 2026 | 4 articles | Viewed by 8908 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Acute Myeloid Leukemia: Current Progress and Future Directions

edited by

Valeria Visconte

and

Luca Guarnera

submission deadline 15 Oct 2026 | 4 articles | Viewed by 8725 | Submission Open

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Care in Pediatric and Neonatal Intensive Care

edited by Tsz Yan Milly Lo, Laura Moss and

Javier Escudero

submission deadline 15 Oct 2026 | 2 articles | Viewed by 4111 | Submission Open

Keywords: pediatric intensive care; neonatal intensive care; AI in intensive care; biomarkers; omics; genetics; precision medicine; personalised medicine; ARDS; mechanical ventilation; haemodynamics; neuromonitoring; sepsis; traumatic brain injury; acquired brain injury; hypoxic ischemic encephalopathy; prematurity; post-operative surgical care; renal replacement therapy; acute kidney injury; cardiomyopathies; congential cardiac disease; multi-modal monitoring; antimicrobial resistance

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Plastic Surgery: New Perspectives and Innovative Techniques

edited by Joseph M. Escandón and

Oscar Javier Manrique

submission deadline 20 Oct 2026 | 7 articles | Viewed by 13823 | Submission Open

Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment

edited by

Abigail Raffner (formerly Basson)

submission deadline 20 Oct 2026 | 5 articles | Viewed by 10445 | Submission Open

Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Gynecology and Obstetrics

edited by

Mǎdǎlin Marius Margan

and

Florin Gorun

submission deadline 20 Oct 2026 | 2 articles | Viewed by 4876 | Submission Open

Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Advances in Oral Health: Innovative and Personalized Approaches

edited by

Eleftherios G. Kaklamanos

, Heleni Vastardis and

Miltiadis A. Makrygiannakis

submission deadline 25 Oct 2026 | 7 articles | Viewed by 17299 | Submission Open

Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Advances in the Use of Machine Learning for Personalized Medicine

edited by

Josip Vrdoljak

submission deadline 25 Oct 2026 | 1 articles | Viewed by 4650 | Submission Open

Keywords: LLMs in medicine; machine learning; deep learning; drug discovery; personalized medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Plastic and Reconstructive Surgery: Challenges and Prospects

edited by Johnny Ionut Efanov and Alain Michel Danino

submission deadline 25 Oct 2026 | 2 articles | Viewed by 2865 | Submission Open

Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Interventional Cardiology and Personalized Medicine

edited by Arnoud W. J. van 't Hof, Pieter A. Vriesendorp and Árpád Lux

submission deadline 25 Oct 2026 | Viewed by 764 | Submission Open

Keywords: coronary artery disease; diffuse CAD; aortic valve stenosis; TAVI; mitraclip; mitral regurgitation; acute coronary syndromes

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine and Management of Gynecologic Cancer

edited by Hooman Soleymani majd and

Federico Ferrari

submission deadline 25 Oct 2026 | Viewed by 567 | Submission Open

Keywords: proteomic; genomic; biomarkers; precision medicine; molecular profiling; immunotherapy; gynecologic cancer

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Bioinformatics and Data Analysis for Common Diseases: Advances in Precision Medicine

edited by

Zhongxue Chen

submission deadline 25 Oct 2026 | Viewed by 331 | Submission Open

Keywords: bioinformatics; statistical genetics; causal inference; meta-analysis; Mendelian randomization; machine learning

(This special issue belongs to the Section Omics/Informatics)

Precision Medicine in Myocardial Infarction: Diagnosis, Prevention, and Treatment

edited by

Camilla Calvieri

submission deadline 25 Oct 2026 | Viewed by 290 | Submission Open

Keywords: precision medicine; myocardial infarction; biomarkers; pharmacogenomics; cardiac imaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Obstetrics and Gynecology and Women's Health—2nd Edition

edited by

Panagiotis N. Tsikouras

submission deadline 26 Oct 2026 | 3 articles | Viewed by 32226 | Submission Open

Keywords: uterine fibroids; uterine myoma; leiomyoma; uterine artery embolization; endometriosis; gynecological surgery; infertility; endocrinology; hysteroscopy; hormonal therapies; personalized medicine

(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)

Personalized Approaches in Spinal Deformity: Innovations in Diagnosis and Treatment

edited by

Mitchell S. Fourman

submission deadline 30 Oct 2026 | 1 articles | Viewed by 2852 | Submission Open

Keywords: adult spinal deformity; preoperative planning; minimally invasive spine surgery; sagittal malalignment; patient-specific hardware; precision medicine; personalized treatment

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Challenges and Opportunities in Personalized Management of Rheumatic Diseases

edited by

Gilda Sandri

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1183 | Submission Open

Keywords: rheumatic diseases; autoimmunity; osteoarthritis; psoriatic arthritis; personalized therapy; immune endotypes; machine learning; musculoskeletal ultrasound; patient preferences; treatment response biomarkers

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Artificial Intelligence and Advanced Medical Imaging in Personalized Medicine

edited by

Paul Andrei Ștefan

and Diana Feier

submission deadline 30 Oct 2026 | Viewed by 417 | Submission Open

Keywords: artificial intelligence; medical imaging; personalized medicine; textural analysis; radiomics

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Recent Research on Personalized Approaches to Clinical Therapeutics and Medication Safety

edited by

Sheraz Ali

submission deadline 31 Oct 2026 | 5 articles | Viewed by 14569 | Submission Open

Keywords: clinical therapeutics; medication safety; pharmacotherapy; personalized medicine; treatment optimization; polypharmacy

(This special issue belongs to the Section Epidemiology)

Clinical Advances and Innovations in Reconstructive and Plastic Surgery

edited by Laura Răducu

submission deadline 31 Oct 2026 | 4 articles | Viewed by 12503 | Submission Open

Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Complications in Vascular Surgery: Current Updates and Perspectives

edited by

Yamume Tshomba

submission deadline 31 Oct 2026 | 4 articles | Viewed by 8231 | Submission Open

Keywords: endoleak; visceral ischaemia; lower limb ischaemia; graft infection; aneurysm shrinkage; sac growing; transient ischemic attack; stroke; deep vein thrombosis; vascular injuries; embolization

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advancing Personalized Medicine: Targeting Oxidative Stress in Neurodegenerative Diseases

edited by Lucia Buccarello

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7956 | Submission Open

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Dermatology: Current Status and Challenges

edited by

Lidia Sacchelli

and

Michelangelo La Placa

submission deadline 31 Oct 2026 | 4 articles | Viewed by 3720 | Submission Open

Keywords: psoriasis; quality of life; acne; hidradenitis suppurativa; biotechnological therapies; personalized medicine; autoimmune skin diseases

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Maternal–Fetal Care: From Cervical Insufficiency to Preterm Birth and Beyond

edited by

Moon-Il Park

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1720 | Submission Open

Keywords: cervical insufficiency; preterm birth; personalized medicine; emergent cerclage; infection-controlled cerclage; maternal–fetal medicine; AI-based prediction platforms

(This special issue belongs to the Section Personalized Medical Care)

Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers

edited by Gustavo Fabregat-Cid

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1164 | Submission Open

Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Artificial Intelligence in Personalized Management of Cardiovascular Diseases

edited by

Dominique J. Monlezun

submission deadline 31 Oct 2026 | Viewed by 528 | Submission Open

Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy, ethics, and governance

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Management for Perioperative Anesthesia

edited by Esther A.C. Bouman

submission deadline 31 Oct 2026 | Viewed by 354 | Submission Open

Keywords: personalized anesthesia; perioperative medicine; precision pain management; artificial intelligence in anesthesia; post-procedural pain; cancer surgery; individualized risk assessment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Insights into Cardiac Electrophysiology and Personalized Medicine

edited by Ioanna Koniari

submission deadline 10 Nov 2026 | 2 articles | Viewed by 1574 | Submission Open

Keywords: ablation; AF; PVI; PFA; ventricular arrhythmias; supraventricular arrhythmias; pacemakers; ICDs; CRT; conduction system pacing

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Treatments in Thoracic Oncology Surgery

edited by

Georg Schlachtenberger

and Alberto Lopez

submission deadline 15 Nov 2026 | 2 articles | Viewed by 4553 | Submission Open

Keywords: minimally invasive surgery; TNM classification; adjuvant treatment; long-term survival

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Medicine in ENT and AI

edited by Cristóbal Langdon

submission deadline 20 Nov 2026 | Viewed by 273 | Submission Open

Keywords: personalized ENT care; precision phenotyping and stratification; clinical decision support (AI-assisted); predictive modeling and outcome forecasting; real-world validation and implementation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Infectious Disease Epidemiology

edited by Cesar Henriquez-Camacho

submission deadline 25 Nov 2026 | 5 articles | Viewed by 9049 | Submission Open

Keywords: infectious diseases; epidemiology; genomics; machine learning; artificial intelligence; surveillance; vaccination; global health; stewardship programs

(This special issue belongs to the Section Epidemiology)

Cancer Biomarker and Molecular Oncology

edited by

Jeane Silva

submission deadline 25 Nov 2026 | 4 articles | Viewed by 7482 | Submission Open

Keywords: cancer biomarkers; molecular oncology; precision medicine; liquid biopsies; therapeutic resistance

(This special issue belongs to the Section Disease Biomarkers)

Precision Medicine in Hematology–Oncology: Recent Progress and Challenges

edited by Anthony M. Hunter and Nikolaos Papadantonakis

submission deadline 25 Nov 2026 | 2 articles | Viewed by 2253 | Submission Open

Keywords: oncology; hematology; precision medicine; personalized medicine; targeted therapy; molecular targets; immunotherapy

(This special issue belongs to the Section Precision Oncology)

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