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Clinical New Insights into Management of Scoliosis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 30 July 2025 | Viewed by 1300

Special Issue Editors


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Guest Editor
Spine Disorders Unit, Department of Spine Disorders and Pediatric Orthopedics, Poznan University of Medical Sciences, 61-545 Poznan, Poland
Interests: scoliosis; idiopathic scoliosis; congenital scoliosis; neuromuscular scoliosis

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Guest Editor
Department of Orthopedics and Rheumoorthopedics, Centre of Postgraduate Medical Education, Professor Adam Gruca Orthopedic and Trauma Teaching Hospital, Konarskiego 13, 05-400 Otwock, Poland
Interests: knee instability; degenerative disease; knee osteoarthritis; arthroplasty; periprosthetic joint infection
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Special Issue Information

Dear Colleagues,

Spine deformations, especially scoliosis, reflect a wide range of complex conditions with different backgrounds and diverse treatment approaches. Despite advancements in understanding their etiology and treatment options, significant gaps persist in optimizing outcomes for patients.

This Special Issue aims to gather the latest clinical and scientific research on scoliosis management, including innovative surgical and non-surgical treatments, rehabilitation techniques, and long-term care strategies. Key areas include understanding the underlying causes, risk factors, and progression patterns of scoliosis, as well as exploring advanced imaging, diagnostic tools, and treatment efficacy. Contributions addressing challenges in patient-specific care and interdisciplinary approaches to improving the quality of life of scoliosis patients and treatment results are particularly welcome.

Additionally, the scope extends to exploring the etiology, background, and underlying basic science of scoliosis.

Researchers and clinicians are invited to contribute studies that push the boundaries of current treatment practices, ensuring a more comprehensive understanding of scoliosis and its management.

This Special Issue aims to provide fresh insights into optimizing patient care and improving treatment outcomes.

Dr. Piotr Janusz
Prof. Dr. Marcin Tyrakowski
Guest Editors

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Keywords

  • scoliosis
  • idiopathic scoliosis
  • congenital scoliosis
  • neuromuscular scoliosis
  • degenerative scoliosis
  • kyphosis
  • spine deformation
  • scoliosis etiology
  • surgical treatment
  • non-surgical treatment

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Published Papers (3 papers)

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Research

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11 pages, 1713 KiB  
Article
Night-Time Bracing Can Reduce Pain in Adults with Scoliosis: Six-Month Results of a Retrospective Controlled Study
by Fabio Zaina, Martina Poggio, Sabrina Donzelli, René Castelein, Francesca Di Felice and Stefano Negrini
J. Clin. Med. 2025, 14(13), 4493; https://doi.org/10.3390/jcm14134493 - 25 Jun 2025
Abstract
Background: Severe scoliosis can lead to chronic low back pain (cLBP) and may progress in adulthood. While day-time bracing is commonly used to alleviate pain and improve function, the role of night-time bracing remains unclear. This study aimed to assess the six-month effectiveness [...] Read more.
Background: Severe scoliosis can lead to chronic low back pain (cLBP) and may progress in adulthood. While day-time bracing is commonly used to alleviate pain and improve function, the role of night-time bracing remains unclear. This study aimed to assess the six-month effectiveness of a custom-made night-time brace in reducing pain in adults with scoliosis, compared to a prefabricated brace worn for 2–4 h during the day. Methods: A retrospective cohort study was conducted at a tertiary outpatient clinic specializing in spinal deformities. Adults with scoliosis (≥30° Cobb) and cLBP were divided into two groups: the study group used a custom-made night-time thoracolumbosacral orthosis (TLSO), while the control group wore a prefabricated brace (Peak) for 2–4 h daily. Pain and functional outcomes were assessed at baseline and after six months. Results: The study group included 25 women (mean age, 62.3 ± 9.5 years; Cobb angle, 60.4 ± 17.7°) who wore the night-time brace for an average of 7.2 ± 2.2 h per night. The control group comprised 20 women (mean age, 67.8 ± 10.5 years; Cobb angle, 61.9 ± 12.6°). At six months, the worst pain significantly improved in the TLSO group compared to the Peak group (F = 6.32, p = 0.0158). However, no statistically significant differences were observed between groups for back pain, leg pain, Core Outcome Measures Index (COMI), or Oswestry Disability Index (ODI). Conclusions: Night-time bracing shows interesting results on pain at six months in adults with severe scoliosis and back pain. These preliminary results open a new perspective that needs further verification and will help design more robust studies to verify what we found and identify the population more responsive to this approach. Full article
(This article belongs to the Special Issue Clinical New Insights into Management of Scoliosis)
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14 pages, 802 KiB  
Article
Risk Factor Analysis for Proximal Junctional Kyphosis in Neuromuscular Scoliosis: A Single-Center Study
by Tobias Lange, Kathrin Boeckenfoerde, Georg Gosheger, Sebastian Bockholt and Albert Schulze Bövingloh
J. Clin. Med. 2025, 14(11), 3646; https://doi.org/10.3390/jcm14113646 - 22 May 2025
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Abstract
Background/Objectives: Proximal junctional kyphosis (PJK) is one of the most frequently discussed complications following corrective surgery in patients with neuromuscular scoliosis (NMS). Despite its clinical relevance, the etiology of PJK remains incompletely understood and appears to be multifactorial. Biomechanical and limited clinical studies [...] Read more.
Background/Objectives: Proximal junctional kyphosis (PJK) is one of the most frequently discussed complications following corrective surgery in patients with neuromuscular scoliosis (NMS). Despite its clinical relevance, the etiology of PJK remains incompletely understood and appears to be multifactorial. Biomechanical and limited clinical studies suggest that preoperative hyperkyphosis, resection of the spinous processes with consequent disruption of posterior ligamentous structures, and rod contouring parameters may contribute as risk factors. Methods: To validate these findings, we retrospectively analyzed 99 NMS patients who underwent posterior spinal fusion using a standardized screw-rod system between 2009 and 2017. Radiographic assessments were conducted at three time points: preoperatively (preOP), postoperatively (postOP), and at a mean follow-up (FU) of 29 months. Clinical variables collected included patient age, weight, height, sex, and Risser sign. Radiographic evaluations encompassed Cobb angles, thoracic kyphosis (TK), lumbar lordosis, the levels of the upper (UIV) and lower (LIV) instrumented vertebrae, the total number of fused segments, parameters of sagittal alignment, the rod contour angle (RCA), and the postoperative mismatch between RCA and the proximal junctional angle (PJA). Based on the development of proximal junctional kyphosis, patients were categorized into PJK and non-PJK groups. Results: The overall incidence of PJK was 23.2%. In line with previous biomechanical findings, spinous process resection was significantly associated with PJK development. Furthermore, the PJK group demonstrated significantly higher preoperative TK (59.3° ± 29.04° vs. 34.5° ± 26.76°, p < 0.001), greater RCA (10.2° ± 4.01° vs. 7.7° ± 4.34°, p = 0.021), and a larger postoperative mismatch between PJA and RCA (PJA−RCA: 3.8° ± 6.76° vs. −1.8° ± 6.55°, p < 0.001) compared to the non-PJK group. Conclusions: Spinous process resection, a pronounced mismatch between postoperative PJA and RCA (odds ratio [OR] = 1.19, p = 0.002), excessive rod bending (i.e., high RCA), and severe preoperative thoracic hyperkyphosis with an expected increase in the risk of PJK of approximately 6.5% per degree of increase in preoperative TK are significant risk factors for PJK. These variables should be carefully considered during the surgical planning and execution of deformity correction in NMS patients. Full article
(This article belongs to the Special Issue Clinical New Insights into Management of Scoliosis)
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Review

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20 pages, 1678 KiB  
Review
Surgical Strategies and Challenges in Scheuermann’s Kyphosis: A Comprehensive Review
by Angelos Kaspiris, Ioannis Spyrou, Fotios Panagopoulos, Vasileios Marougklianis, Periklis Pelantis, Michail Vavourakis, Evangelos Sakellariou, Ioanna Lianou, Dimitrios Ntourantonis, Thomas Repantis, Elias S. Vasiliadis and Spiros G. Pneumaticos
J. Clin. Med. 2025, 14(12), 4276; https://doi.org/10.3390/jcm14124276 - 16 Jun 2025
Viewed by 624
Abstract
Background: Scheuermann’s kyphosis (SK) is characterized by anterior wedging of >5 degrees at three or more contiguous vertebrae associated with severe back pain and cosmetic disfigurement. Different surgical interventions have been applied for SK correction, but the optimal operational treatment remains controversial. [...] Read more.
Background: Scheuermann’s kyphosis (SK) is characterized by anterior wedging of >5 degrees at three or more contiguous vertebrae associated with severe back pain and cosmetic disfigurement. Different surgical interventions have been applied for SK correction, but the optimal operational treatment remains controversial. Objectives: The aim of our study is to analyze all the current indications for the surgical correction of SK, as well as to describe the instrumentation methods and techniques in order to detect the ideal operational management and accompanied complications. Methods: This comprehensive review investigates the up-to-date surgical indications and approaches for SK, the current trends, and the associated postoperative functional outcomes. A detailed search of PubMed, Web of Science and Google Scholar databases in English literature was performed for articles during the last 20 years. Additional criteria were peer-reviewed original studies that provided the type of interventions for SK and the clinical outcomes. Results: Thirty studies that met our induction criteria were analyzed. The up-to-date surgical indications such as back pain, failure of conservative treatment, progression of deformity, and neurological complications were described. Anterior (AO) and posterior-only (PO), and combined anterior–posterior (AP) approaches and instrumentation techniques were outlined. The most common side effects of the above interventions were hardware failure, loss of correction and Proximal Junctional Kyphosis. Contrariwise, in PO, reduced blood loss and operational duration was noted. Conclusions: Although the published studies reported contradictory results of the effectiveness of the various techniques applied for SK treatment, the PO fusion was correlated with a decreased rate of complications that resulted in its current increase in popularity. Full article
(This article belongs to the Special Issue Clinical New Insights into Management of Scoliosis)
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