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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management

edited by Emelina Stambolliu and Antonios A. Argyris

submission deadline 20 Nov 2025 | 6 articles | Viewed by 47218

Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds

(This special issue belongs to the Section Vascular Medicine)

Association Between Sleep Disorders and Diabetes

edited by

Patrizio Tatti

and Desiderio Passàli

submission deadline 20 Nov 2025 | 3 articles | Viewed by 24911

Keywords: diabetes; OSAS; complications; insulin; resistance

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Advances in Vascular and Endovascular Surgery

edited by Toshifumi Kudo

submission deadline 20 Nov 2025 | 11 articles | Viewed by 23400

Keywords: aortic aneurysm; peripheral arterial disease; chronic limb-threatening ischemia; endovascular aneurysm repair; endovascular treatment; non-invasive blood flow measurements; varicose veins; deep venous thrombosis

(This special issue belongs to the Section Vascular Medicine)

Advances in Trauma and Orthopedic Surgery: 2nd Edition

edited by

Christian von Rüden

submission deadline 20 Nov 2025 | 12 articles | Viewed by 23375

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Thromboembolic Disease and Antithrombotic Therapy

edited by Prahlad Ho

submission deadline 20 Nov 2025 | 6 articles | Viewed by 23325

Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein thrombosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Virchow’ s triad; post thrombotic syndrome

(This special issue belongs to the Section Hematology)

Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease

edited by Joseph B. Selvanayagam and

Sivabaskari Pasupathy

submission deadline 20 Nov 2025 | 10 articles | Viewed by 20551

Keywords: personalized medicine; cardiovascular innovations; cardiac imaging; risk assessment; multimodal imaging; therapeutic strategies; data-driven decision making; clinical outcomes; translational research

(This special issue belongs to the Section Cardiovascular Medicine)

New Clinical Advances in Chronic Asthma

edited by Vitaliano Nicola Quaranta

submission deadline 20 Nov 2025 | 7 articles | Viewed by 16074

Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids

(This special issue belongs to the Section Respiratory Medicine)

Sports Injury Treatment: Innovations in Pain Management, Recovery, and Performance Optimization

edited by Antonio P. Veloso and Javad Sarvestan

submission deadline 20 Nov 2025 | 2 articles | Viewed by 12300

Keywords: sports injury treatment; pain management; recovery optimization; performance enhancement; advanced rehabilitation; injury prevention; biomechanics; neuromechanics; novel pain relief modalities; performance recovery strategies; wearable technology

(This special issue belongs to the Section Sports Medicine)

Pelvic Organ Prolapse: Current Progress and Clinical Challenges

edited by

Riccardo Lombardo

and Cosimo De Nunzio

submission deadline 20 Nov 2025 | 5 articles | Viewed by 10631

Keywords: pelvic organ prolapse (POP); postmenopausal; urinary dysfunction; minimally invasive surgery; laparoscopic surgery; robotic surgery; surgical mesh

(This special issue belongs to the Section Obstetrics & Gynecology)

Complex Orthopedic Trauma: Diagnosis, Treatment, Managing Complications and Rehabilitation

edited by Philip-Christian Nolte and Benedict Swartman

submission deadline 20 Nov 2025 | 6 articles | Viewed by 10229

Keywords: orthopedic trauma; fracture; complications; infection; bone; rehabilitation

(This special issue belongs to the Section Orthopedics)

The Association Between Sleep Disorders and Metabolic and Mental Health

edited by

Filip Franciszek Karuga

Piotr Bialasiewicz

and

Marcin Sochal

submission deadline 20 Nov 2025 | 5 articles | Viewed by 10217

Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health

(This special issue belongs to the Section Mental Health)

Clinical Research of Novel Therapeutic Approaches in Dentistry (2nd Edition)

edited by

Jacek Matys

Kinga Grzech-Lesniak

and

Tomasz Gedrange

submission deadline 20 Nov 2025 | 6 articles | Viewed by 9673

Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; dentistry; biological safety

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiac Imaging in the Diagnosis and Management of Heart Failure

edited by Mahi Lakshmi Ashwath and Allen S. Anderson

submission deadline 20 Nov 2025 | 2 articles | Viewed by 8030

Keywords: echocardiography; cardiac MRI; myocardial viability; tissue characterization; ischemic and non-ischemic cardiomyopathy; HFpEF; myocardial strain

(This special issue belongs to the Section Cardiology)

State of the Art in Neuromodulation or Spinal Cord Stimulation Therapy

edited by Marco Mercieri

submission deadline 20 Nov 2025 | 3 articles | Viewed by 6964

Keywords: neuromodulation; spinal cord stimulation; chronic pain management; stimulation waveforms; long-term efficacy; loss of efficacy; outcome prediction; opioid-sparing techniques; neurostimulation mechanisms; psychological predictors; therapeutic targets

(This special issue belongs to the Section Clinical Neurology)

Cardiopulmonary Resuscitation—from Research to Clinical Implementation

edited by

Endre Zima

submission deadline 20 Nov 2025 | 4 articles | Viewed by 5827

Keywords: cardiopulmonary resuscitation; cardiac arrest; basic life support; advanced life support; special circumstances; target temperature management; eCPR-ECLS; survival

(This special issue belongs to the Section Emergency Medicine)

Current State of Breast Reconstruction

edited by

Il-Kug Kim

submission deadline 20 Nov 2025 | 3 articles | Viewed by 5113

Keywords: breast reconstruction; silicone implant; autologous tissue; acellular dermal matrix; seroma; outcome; complication; patient satisfaction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Orthopedic Infections

edited by

Hyonmin Choe

submission deadline 20 Nov 2025 | 4 articles | Viewed by 4938

Keywords: orthopedic surgery; orthopedic infections; periprosthetic joint infection; surgical site infection; infection management

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis and Treatment of Heart Failure

edited by

Noel Lorenzo-Villalba

and

Manuel Montero-Perez-Barquero

submission deadline 20 Nov 2025 | 4 articles | Viewed by 4712

Keywords: heart failure; diagnosis; treatment; elderly; pluripathology

(This special issue belongs to the Section Cardiology)

Clinical Updates in Lung Ultrasound

edited by

Lior Fuchs

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4075

Keywords: lung ultrasound; intensive care; imaging; ARDS; POCUS

(This special issue belongs to the Section Respiratory Medicine)

PET Imaging in Bone and Non-Bone Diseases

edited by

Tanuj Puri

and

Glen Blake

submission deadline 20 Nov 2025 | 2 articles | Viewed by 4044

Keywords: PET; bone metabolism; bone diseases; metabolic bone diseases; image analysis; radiomics; artificial intelligence

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Arthritis: From Diagnosis to Treatment

edited by Andrea Di Matteo and

Kulveer Mankia

submission deadline 20 Nov 2025 | 6 articles | Viewed by 3936

Keywords: rheumatoid arthritis; psoriatic arthritis; imaging; ultrasound; DMARDs; differential diagnosis; difficult to treat rheumatoid arthritis; prevention

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Perspectives in Reconstructive Urethral Surgery

edited by Krishnan Venkatesan

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3858

Keywords: urethral reconstruction; urethroplasty; urethral stricture; bladder neck stenosis; urinary fistula

(This special issue belongs to the Section Nephrology & Urology)

Aortic Valve Implantation: Recent Advances and Future Prospects

edited by Suvitesh Luthra and Richard Jabbour

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3485

Keywords: aortic valve replacement; aortic stenosis; paravalvular leak; coronary and structural interventional cardiology; percutaneous coronary artery interventions

(This special issue belongs to the Section Cardiology)

Challenges in Fertility Preservation

edited by

Loris Marin

and Guido Ambrosini

submission deadline 20 Nov 2025 | 2 articles | Viewed by 3188

Keywords: fertility preservation; oocytes cryopreservation; embryo cryopreservation; ovarian tissue transplantation; gonadotoxic therapy

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Challenges and Opportunities in Geriatric Nephrology and Urology

edited by Giulio Romano

submission deadline 20 Nov 2025 | 1 articles | Viewed by 2111

Keywords: kidney disease; elderly patient; epidemiology; pharmacological therapy; lifestyle diet

(This special issue belongs to the Section Nephrology & Urology)

Targeted Diagnosis and Treatment of Shoulder and Elbow Disease: 2nd Edition

edited by

Teresa Paolucci

and

Massimiliano Mangone

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1767

Keywords: anterolateral deltoid split; joint pain; axillary nerve injury; rotator cuff injuries; shoulder arthroplasty; shoulder impingement syndrome; proximal humeral fracture; rehabilitation; exercise; physiotherapy; rehabilitative relapses

(This special issue belongs to the Section Orthopedics)

Current Status and Future Directions in Cardiac Surgery

edited by Marie-Elisabeth Stelzmüller and Randolph H.L. Wong

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1598

Keywords: innovations; AI; minimally invasive; endoscopic; novel technologies in electrophysiology; hybrid procedures; inno-vative approaches in cardiac surgery and patient care

(This special issue belongs to the Section Cardiology)

Future Directions in Imaging-Guided Glaucoma Diagnosis and Therapy

edited by

Takuhei Shoji

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1579

Keywords: optical coherence tomography; optical coherence tomography angiography; visual field testing; glaucoma surgery; MIGS; structure– function relationship in glaucoma

(This special issue belongs to the Section Ophthalmology)

Advances in Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis

edited by

Roberto Carbone

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1518

Keywords: pulmonary hypertension; interstitial lung disease; idiopathic pulmonary fibrosis; heart failure; mitral valve disease

(This special issue belongs to the Section Respiratory Medicine)

Latest Advances in Glaucoma, Cataract and Refractive Surgery: Expert Views, 2nd Edition

edited by

Jose Angel Fernandez-Vigo

and

Enrique Santos-Bueso

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1403

Keywords: refractive surgery; glaucoma; cataract; intraocular lenses; diagnostic imaging

(This special issue belongs to the Section Ophthalmology)

State-of-the-Art Research on Thoracic Surgery

edited by

Russell Seth Martins

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1258

Keywords: 3D imaging; surgical process optimization; robotic surgery; immunotherapy and targeted therapy; novel cancer detection methods; personalized treatment

(This special issue belongs to the Section General Surgery)

Acute Ischemic Stroke Management Strategies

edited by

Marta Iacobucci

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1154

Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra

(This special issue belongs to the Section Clinical Neurology)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1142

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Procedures for Diagnosis and Treatment of Cardiovascular Diseases

edited by Ahmad Jabri, Mohammad Alqarqaz, Qais Radaideh and Ahmad Al-Abdouh

submission deadline 20 Nov 2025 | 1 articles | Viewed by 943

Keywords: cardiovascular disease; diagnostic imaging; minimally invasive procedures; precision medicine; artificial intelligence; interventional cardiology; surgical innovations; patient outcomes; preventive cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Skin Wound Healing: Clinical Updates and Perspectives

edited by

András Bánvölgyi

and

Norbert Kiss

submission deadline 20 Nov 2025 | 1 articles | Viewed by 941

Keywords: dermatology; wound care; diagnosis; biomaterials; negative pressure wound therapy

(This special issue belongs to the Section Dermatology)

Diagnosis and Treatment of Ocular Surface Diseases

edited by

Stuti Misra

and

Sònia Travé-Huarte

submission deadline 20 Nov 2025 | 1 articles | Viewed by 873

Keywords: dry eye disease; ocular surface; anterior segment imaging; biomarkers; artificial intelligence; diagnostic tools; novel therapeutic agents; anterior eye care

(This special issue belongs to the Section Ophthalmology)

Low Back Pain: Clinical Treatment and Management

edited by

Raffaello Pellegrino

and

Angelo Di Iorio

submission deadline 20 Nov 2025 | 1 articles | Viewed by 841

Keywords: exercise; rehabilitation; weight loss; telerehabilitation; pain; physical therapy; treatment; conservative treatment; intervertebral disk displacement; low back pain; sciatica

(This special issue belongs to the Section Clinical Neurology)

Challenges and Future Trends in Bariatric Surgery

edited by Maurizio L. de Luca and Amanda Belluzzi

submission deadline 20 Nov 2025 | Viewed by 419

Keywords: metabolic and bariatric surgery; SADI-S; LSG; RYGB; SASI; OAGB; complications after MBS; long-term outcomes; malnutrition

(This special issue belongs to the Section General Surgery)

Clinical Research in Management of Corneal Diseases

edited by Massimo Busin and Angeli Christy Yu

submission deadline 20 Nov 2025 | 1 articles | Viewed by 388

Keywords: corneal surgery; corneal transplant; lamellar keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; descemet stripping automated endothelial keratoplasty; corneal neurotization

(This special issue belongs to the Section Ophthalmology)

Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological Aspects

edited by

Hideaki Kanemura

submission deadline 20 Nov 2025 | Viewed by 346

Keywords: quality of life (QOL); cognition; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); social

(This special issue belongs to the Section Clinical Neurology)

Minimally Invasive Techniques in Digestive Pathologies

edited by

Octavian Andronic

submission deadline 20 Nov 2025 | Viewed by 233

Keywords: minimally invasive surgery; laparoscopic techniques; robotic surgery; endoscopic interventions; hybrid surgical approaches; digestive oncology; AI in surgery; surgical innovation; gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Nov 2025 | Viewed by 205

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

Diagnosis and Treatment of Scoliosis and Spinal Deformity

edited by Anna Rienmueller and Kenny Yat Hong Kwan

submission deadline 20 Nov 2025 | Viewed by 174

Keywords: scoliosis; spinal deformity; adolescent idiopathic scoliosis (AIS); early onset scoliosis (EOS); neuromuscular scoliosis; adult spinal deformity (ASD); operative treatment; spinal fusion; neuromonitoring in scoliosis and deformity surgery; perioperative risk factors; conservative treatment; bracing therapy; physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy; spinal biomechanics; scoliosis imaging; low-dose radiation imaging; artificial intelligence in scoliosis; 3D modelling in spinal deformity including surgical planning; predictive modelling in scoliosis progression; biomechanics of spinal curvature; growth modulation; patient-reported outcomes in scoliosis treatment

(This special issue belongs to the Section Orthopedics)

Effect of Long-Term Insomnia on Mental Health—2nd Edition

edited by

Aleksandra Rogowska

submission deadline 21 Nov 2025 | 1 articles | Viewed by 6894 | Submission Open

Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress

(This special issue belongs to the Section Mental Health)

Research Advances in Coagulation Disorders

edited by Alberto Maino

submission deadline 21 Nov 2025 | Viewed by 182 | Submission Open

Keywords: coagulation; bleeding disorders; thrombosis; hemophilia; clotting disorders; hematology

(This special issue belongs to the Section Hematology)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 23 Nov 2025 | 4 articles | Viewed by 8999 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Clinical Management of Type 1 Diabetes

edited by Carmen Quirós

submission deadline 25 Nov 2025 | 7 articles | Viewed by 30641 | Submission Open

Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens

(This special issue belongs to the Section Endocrinology & Metabolism)

The “Orthogeriatric Fracture Syndrome”—Issues and Perspectives

edited by

Johannes Dominik Bastian

submission deadline 25 Nov 2025 | 18 articles | Viewed by 29459 | Submission Open

Keywords: geriatric trauma; fragility fracture; orthogeriatric; co-management; assessment; integrated care; osteoporosis; sarcopenia; frailty; gait disturbance; fall; rehabilitation; prehabilitation; prevention; ehealth; digitalization

(This special issue belongs to the Section Orthopedics)

Perinatal Mental Health Management

edited by

Sigita Lesinskienë

submission deadline 25 Nov 2025 | 5 articles | Viewed by 20146 | Submission Open

Keywords: perinatal mental health; child mental health; problem behavior; cognitive development therapy; hyperactivity

(This special issue belongs to the Section Mental Health)

Neurovascular Diseases: Clinical Advances and Challenges

edited by

Roberto Colasanti

, Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez

submission deadline 25 Nov 2025 | 11 articles | Viewed by 20146 | Submission Open

Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms

(This special issue belongs to the Section Clinical Neurology)

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