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Diagnosis and Treatment of Scoliosis and Spinal Deformity

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (20 November 2025) | Viewed by 1400

Special Issue Editors


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Guest Editor
Department of Orthopaedics and Trauma Surgery, Division of Orthopaedics, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria
Interests: scoliosis; adult spinal deformity; neuromonitoring; cervical spine; biological age

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Guest Editor
Department of Orthopaedics and Traumatology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Interests: basic and clinical research into adult and paediatric spine deformity

Special Issue Information

Dear Colleagues,

Scoliosis and other spinal deformities across pediatric, adolescent, and adult populations pose significant clinical challenges. Effective management requires a multidisciplinary approach combining surgery, conservative care, advanced imaging, and translational research. This Special Issue invites cutting-edge research on all scoliosis types—idiopathic, congenital, neuromuscular, syndromic, degenerative, early-onset, and functional.

We welcome original articles and reviews focusing on the following:

  • Operative Management: Innovative surgical techniques, neuromonitoring, perioperative care, and long-term outcomes.
  • Conservative Strategies: Advances in bracing (e.g., 3D-printed), scoliosis-specific exercises (PSSE), and non-surgical care for early-onset or progressive scoliosis.
  • Imaging & Diagnostics: advanced imaging techniques, 3D modeling, AI-assisted planning, and predictive tools for curve progression.

Key aims include the following:

  • Illustrating advances in both surgical and non-surgical scoliosis treatment;
  • Highlighting imaging and AI tools for improved diagnosis and planning;
  • Encouraging interdisciplinary collaboration to optimize outcomes.

This Special Issue offers a platform for spine specialists, clinicians, and researchers to share innovations that will shape the future of scoliosis care. We especially encourage submissions on novel treatment approaches, surgical techniques, and outcome-improvement strategies.

Submit your manuscript to help advance scoliosis research and clinical care.

Dr. Anna Rienmueller
Dr. Kenny Yat Hong Kwan
Guest Editors

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • scoliosis
  • spinal deformity
  • adolescent idiopathic scoliosis (AIS)
  • early onset scoliosis (EOS)
  • neuromuscular scoliosis
  • adult spinal deformity (ASD)
  • operative treatment
  • spinal fusion
  • neuromonitoring in scoliosis and deformity surgery
  • perioperative risk factors
  • conservative treatment
  • bracing therapy
  • physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy
  • spinal biomechanics
  • scoliosis imaging
  • low-dose radiation imaging
  • artificial intelligence in scoliosis
  • 3D modelling in spinal deformity including surgical planning
  • predictive modelling in scoliosis progression
  • biomechanics of spinal curvature
  • growth modulation
  • patient-reported outcomes in scoliosis treatment

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Published Papers (2 papers)

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Research

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15 pages, 1849 KB  
Article
Association Between Lower Instrumented Vertebra Selection and Mechanical Complications After Surgical Correction for Kyphotic Deformity Following Osteoporotic Vertebral Fracture
by Keishi Maruo, Fumihiro Arizumi, Kazuya Kishima, Tetsuto Yamaura, Masaru Hatano, Hayato Oishi and Toshiya Tachibana
J. Clin. Med. 2026, 15(5), 1731; https://doi.org/10.3390/jcm15051731 - 25 Feb 2026
Viewed by 258
Abstract
Background: Kyphotic deformity following osteoporotic vertebral fracture (KDOVF) often requires corrective surgery to restore sagittal alignment; however, mechanical complications, such as proximal junctional failure (PJF) and distal junctional failure (DJF), remain major concerns. Selection of the lower instrumented vertebra (LIV) plays a [...] Read more.
Background: Kyphotic deformity following osteoporotic vertebral fracture (KDOVF) often requires corrective surgery to restore sagittal alignment; however, mechanical complications, such as proximal junctional failure (PJF) and distal junctional failure (DJF), remain major concerns. Selection of the lower instrumented vertebra (LIV) plays a critical role in balancing mechanical stability and functional preservation; however, the optimal criteria for LIV selection have not been fully established. Methods: This multicenter retrospective cohort study included 52 patients who underwent corrective surgery for KDOVF, with a minimum 1-year follow-up. The patients were classified into a long-fixation group with pelvic fixation (n = 27) and a short-fixation group with lumbar LIV fixation (n = 25). Mechanical complications, radiographic parameters, patient-reported outcomes, and paraspinal muscle fatty degeneration were compared between groups. Subgroup analysis was performed within the short-fixation group to identify the factors associated with DJF. Results: The incidence of PJF was significantly higher in the long-fixation group than in the short-fixation group (37% vs. 8%, p < 0.01), whereas DJF was observed only in the short-fixation group (24%). Within the short-fixation group, patients who developed DJF demonstrated significantly greater preoperative sagittal malalignment, a lower rate of cement-augmented pedicle screw, and more advanced fatty degeneration of the paraspinal muscles. The short-fixation group also showed better postoperative lumbar function. Conclusions: LIV selection in KDOVF surgery is associated with distinct patterns of junctional mechanical complications. Short fixation may be feasible in carefully selected patients who demonstrate preserved compensatory capacity. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Scoliosis and Spinal Deformity)
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Review

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19 pages, 1671 KB  
Review
The Development of Spinal Deformity in Patients with Duchenne Muscular Dystrophy: Clinical Assessment, Surgical Considerations and Recommendations for Treatment
by Athanasios I. Tsirikos and Simon B. Roberts
J. Clin. Med. 2026, 15(6), 2116; https://doi.org/10.3390/jcm15062116 - 10 Mar 2026
Viewed by 860
Abstract
Duchenne muscular dystrophy (DMD) causes progressive skeletal, respiratory and cardiac muscle weakness in affected males. Most DMD patients develop scoliosis following loss of ambulation. This narrative review describes recommendations for the management of scoliosis in DMD patients using a review of the current [...] Read more.
Duchenne muscular dystrophy (DMD) causes progressive skeletal, respiratory and cardiac muscle weakness in affected males. Most DMD patients develop scoliosis following loss of ambulation. This narrative review describes recommendations for the management of scoliosis in DMD patients using a review of the current literature evidence and a consensus review by the DMD Care UK Spinal Surgery Working Group. Advances in medical treatments have improved life expectancy for DMD patients. Spinal bracing is not effective in preventing the deterioration of scoliosis. Seating and wheelchair adaptations can provide postural support. The multidisciplinary assessment of patients with DMD requiring treatment for scoliosis is reviewed, with particular focus on bone, cardiac and respiratory health. The indications, surgical techniques, and type of spinal instrumentation for surgical management for progressively severe scoliosis with or without pelvic obliquity are discussed. Anaesthetic techniques, intraoperative neuromonitoring, perioperative care, and postoperative management in the ICU are discussed for the optimal management of DMD patients undergoing surgery to correct spinal deformity. Finally, regional and holistic functional assessments, patient satisfaction and long-term health, quality of life, and life expectancy for DMD patients undergoing treatment for spinal deformity are reviewed. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Scoliosis and Spinal Deformity)
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