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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Apr 2027 | 4 articles | Viewed by 3174 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Apr 2027 | 4 articles | Viewed by 2564 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics

edited by

Nicoletta Cerundolo

and

Carmine Siniscalchi

submission deadline 20 Apr 2027 | 4 articles | Viewed by 2508 | Submission Open

Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care

(This special issue belongs to the Section Geriatric Medicine)

Advances in Cardiac Surgery: Techniques, Outcomes, and Innovations

edited by

Marius-Mihai Harpa

, Horatiu Suciu and

Emil Marian Arbanasi

submission deadline 20 Apr 2027 | 5 articles | Viewed by 2492 | Submission Open

Keywords: endoscopic cardiac surgery; minimally invasive cardiac surgery; MIMS; mini-AVR; MIDCAB; TCRAT; LVAD; heart transplant; congenital heart disease

(This special issue belongs to the Section Cardiology)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Apr 2027 | 1 articles | Viewed by 2414 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2397 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Apr 2027 | 2 articles | Viewed by 2126 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Clinical Updates and Perspectives in Atrial Fibrillation

edited by Riyaz Somani and

Ibrahim Antoun

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2119 | Submission Open

Keywords: atrial fibrillation; catheter ablation; risk prediction; stroke prevention; digital health and artificial intelligence

(This special issue belongs to the Section Cardiology)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Apr 2027 | 3 articles | Viewed by 2045 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Apr 2027 | 4 articles | Viewed by 1964 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Spine Surgery and Postoperative Management

edited by Mitchell K. Ng

submission deadline 20 Apr 2027 | 3 articles | Viewed by 1788 | Submission Open

Keywords: spine surgery; perioperative care; enhanced recovery after surgery (ERAS); multimodal analgesia; opioid-sparing strategies; neuromonitoring; perioperative optimization

(This special issue belongs to the Section Orthopedics)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Apr 2027 | 3 articles | Viewed by 1720 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

New Developments and Challenges in Assisted Reproductive Technology

edited by

Shuqin Wei

and

Justin Tan

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1656 | Submission Open

Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1647 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Electrotherapy and Electrodiagnostic in Modern Rehabilitation Medicine: Current Evidence, Clinical Applications, and Future Perspectives

edited by Cristina Octaviana Daia

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1600 | Submission Open

Keywords: electrotherapy; physical and rehabilitation medicine; rehabilitation technologies; neurorehabilitation; cancer rehabilitation; electromyography; nerve conduction studies; musculoskeletal ultrasound; photobiomodula-tion; neuromuscular electrical stimulation; therapeutic ultrasound; extracorporeal shockwave therapy; electromagnetic field therapy; TECAR therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1533 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges

edited by

Roberto Cirocchi

submission deadline 20 Apr 2027 | 1 articles | Viewed by 1443 | Submission Open

Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Trends and Progress in Eating Disorders and Obesity Management

edited by Davide Gravina,

Claudia Carmassi

and

Maria Livanou

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1131 | Submission Open

Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics

(This special issue belongs to the Section Mental Health)

Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management

edited by

Wojciech Gawȩcki

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1094 | Submission Open

Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic

(This special issue belongs to the Section Otolaryngology)

Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes

edited by Kevin Liou

submission deadline 20 Apr 2027 | 1 articles | Viewed by 989 | Submission Open

Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI

(This special issue belongs to the Section Cardiology)

Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction

edited by

Rita Pavasini

submission deadline 20 Apr 2027 | 1 articles | Viewed by 974 | Submission Open

Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Advanced Coronary Physiology and Imaging-Guided Percutaneous Cardiovascular Interventions: Treatment Approaches and Outcomes

edited by Ioannis Skalidis

submission deadline 20 Apr 2027 | 1 articles | Viewed by 944 | Submission Open

Keywords: acute coronary syndromes; chronic coronary syndromes; coronary physiology; intravascular imaging; artificial in-telligence; percutaneous coronary intervention; complex coronary disease

(This special issue belongs to the Section Cardiology)

Exploring Female Infertility: Advances, Challenges, and Emerging Solutions

edited by

Claire Ann Jones

submission deadline 20 Apr 2027 | 2 articles | Viewed by 922 | Submission Open

Keywords: infertility; female infertility; in vitro fertilization; PCOS; assisted reproductive technology

(This special issue belongs to the Section Obstetrics & Gynecology)

Breaking the Barrier: Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC)

edited by

Ewa Małecka-Wojciesko

submission deadline 20 Apr 2027 | 1 articles | Viewed by 844 | Submission Open

Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatic cancer; IPMN; PDAC screening; early PDAC detection; PDAC biomarkers; CT; NMR

(This special issue belongs to the Section Oncology)

Physiotherapy: Multidisciplinary Interventions and Digital Health

edited by

Esteban Obrero-Gaitán

and

Irene Cortés Pérez

submission deadline 20 Apr 2027 | 1 articles | Viewed by 823 | Submission Open

Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal, neurological, cognitive, pediatric, pulmonary, cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults

(This special issue belongs to the Section Clinical Rehabilitation)

Spine Surgery: Clinical Advances and Future Directions—2nd Edition

edited by Eun-Sang Kim and

Seung-Kook Kim

submission deadline 20 Apr 2027 | 1 articles | Viewed by 821 | Submission Open

Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain

(This special issue belongs to the Section Clinical Neurology)

Hepatobiliary–Pancreatic Surgery in the Era of Interventional Radiology

edited by

Dimitrios Giannis

submission deadline 20 Apr 2027 | 1 articles | Viewed by 805 | Submission Open

Keywords: hepato-biliary–pancreatic surgery; interventional radiology; percutaneous biliary drainage; percutaneous pancre-atic drainage; portal vein embolization; tumor ablation; minimally invasive surgery; cryoablation; thermoablation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Anterior Segment Disorders

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Apr 2027 | 1 articles | Viewed by 763 | Submission Open

Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life

(This special issue belongs to the Section Ophthalmology)

Current Practice and Future Directions in Hemodialysis and Peritoneal Dialysis

edited by

Johannes Wild

submission deadline 20 Apr 2027 | 1 articles | Viewed by 747 | Submission Open

Keywords: kidney replacement therapy; hemodialysis; peritoneal dialysis; dialysis nursing; continuous renal replacement therapy; incremental dialysis; decremental dialysis

(This special issue belongs to the Section Nephrology & Urology)

Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation

edited by Michele Finotti and Francesco D’Amico

submission deadline 20 Apr 2027 | 1 articles | Viewed by 711 | Submission Open

Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Rehabilitation and Musculoskeletal Health

edited by

Magdalena Rodica Traistaru

Roxana Miclaus

and Daniela Matei

submission deadline 20 Apr 2027 | 1 articles | Viewed by 606 | Submission Open

Keywords: musculoskeletal disorders; musculoskeletal rehabilitation; physical medicine and rehabilitation; pain management; osteoarthritis; functional recovery; disability assessment; therapeutic exercise; physiotherapy; sports injuries; ultra-sound in rehabilitation; quality of life; well-being

(This special issue belongs to the Section Clinical Rehabilitation)

Advances and Future Perspectives for Transcatheter Aortic Valve Replacement (TAVR)

edited by Kyriakos Spiliopoulos and Nikolaos Liaros

submission deadline 20 Apr 2027 | 1 articles | Viewed by 579 | Submission Open

Keywords: aortic stenosis; aortic valve replacement; transcatheter aortic valve replacement (TAVR); “Valve in Valve” procedure; TAVR-endocarditis; TAVR-durability; TAVR-design; cardiovascular imaging

(This special issue belongs to the Section Cardiology)

Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders

edited by

Joshua M. Nadeau

and Andrea D. Guastello

submission deadline 20 Apr 2027 | 1 articles | Viewed by 570 | Submission Open

Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment

(This special issue belongs to the Section Mental Health)

Personalised and Precision Pharmacotherapy: Data-Driven Therapeutic Optimisation in Real-World Clinical Practice

edited by

Fátima Roque

and

Ignatios Ioakeim-Skoufa

submission deadline 20 Apr 2027 | 1 articles | Viewed by 563 | Submission Open

Keywords: precision pharmacotherapy; personalised medicine ; pharmacokinetics and pharmacodynamics ; therapeutic drug ; monitoring real-world evidence ; multimorbidity ; medication appropriateness ; model-informed precision dosing; does individualisation; clinical decision support

(This special issue belongs to the Section Pharmacology)

Emerging Technologies in Foot and Ankle Care: From Advanced Diagnosis to Innovative Treatment

edited by Jaehwang Song

submission deadline 20 Apr 2027 | 1 articles | Viewed by 451 | Submission Open

Keywords: foot; ankle; tendon; ligament; disease; MIS; deformity correction; flatfoot; cavovarus foot; WBCT

(This special issue belongs to the Section Orthopedics)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Apr 2027 | Viewed by 381 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

The Liver–Kidney Axis in Metabolic Diseases: Biomarkers and Clinical Implications

edited by

Anna Di Sessa

submission deadline 20 Apr 2027 | Viewed by 375 | Submission Open

Keywords: liver; kidney; cross-organ crosstalk; mechanisms; biomarkers; metabolic diseases; clinical implications

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advancements in Urolithiasis Surgery: Current Trends and Future Directions

edited by

Asaf Shvero

and Nir Kleinmann

submission deadline 20 Apr 2027 | 1 articles | Viewed by 361 | Submission Open

Keywords: urolithiasis; ureterocopy; laser; PCNL; ESWL; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation

edited by

Laura Scaramuzzo

submission deadline 20 Apr 2027 | Viewed by 356 | Submission Open

Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery

(This special issue belongs to the Section Orthopedics)

Advances in Clinical Oncologic Diagnostic and Interventional Radiology

edited by Alberta Cappelli

submission deadline 20 Apr 2027 | 1 articles | Viewed by 343 | Submission Open

Keywords: artificial intelligence; oncological imaging; hybrid imaging; endovascular radiology; percutaneous procedures; radiomics; MRI; CT; PET/CT; photon counting CT; cone-beam CT

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition

edited by

Edoardo Conte

submission deadline 20 Apr 2027 | Viewed by 336 | Submission Open

Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Approaches of Intracranial Aneurysm and Subarachnoid Hemorrhage

edited by Sylvia Bele

submission deadline 20 Apr 2027 | Viewed by 310 | Submission Open

Keywords: aSAH; clipping or coiling; extracranial complications; cerebral vasospasm; ICU treatment

(This special issue belongs to the Section Clinical Neurology)

Recent Advances in Hypercholesterolemia

edited by Ana Catarina Alves

submission deadline 20 Apr 2027 | Viewed by 307 | Submission Open

Keywords: hypercholesterolemia; cardiovascular risk; molecular diagnostics; variants of uncertain significance (VUS); functional characterisation; precision medicine; lipid-lowering therapy

(This special issue belongs to the Section Endocrinology & Metabolism)

From Imaging to Intervention: Modern Approaches in Spine Disorders Management

edited by

Maria Chiara Maccarone

submission deadline 20 Apr 2027 | Viewed by 303 | Submission Open

Keywords: adolescent idiopathic scoliosis (AIS); spinal fusion; Cobb angle; bracing; skeletal maturity; radiographic imaging; multidisciplinary management

(This special issue belongs to the Section Orthopedics)

Managing Chronic Kidney Disease: Current Practices and Future Perspectives

edited by Maria L. Gonzalez-Suarez

submission deadline 20 Apr 2027 | Viewed by 302 | Submission Open

Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Diagnosis and Treatment of Metastatic Spinal Tumor

edited by

Takeo Furuya

submission deadline 20 Apr 2027 | Viewed by 297 | Submission Open

Keywords: metastatic spinal tumors; spine surgery; bone metastasis; imaging diagnosis; minimally invasive surgery; decompression surgery; fixation surgery; emergency surgery; prognosis prediction; elderly patients; nutrition; mental health

(This special issue belongs to the Section Oncology)

Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management—Second Edition

edited by Emelina Stambolliu and Antonios A. Argyris

submission deadline 20 Apr 2027 | Viewed by 285 | Submission Open

Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds

(This special issue belongs to the Section Vascular Medicine)

Targeting Extravalvular Burden Associated with Valvular Heart Disease

edited by

Giovanni La Canna

submission deadline 20 Apr 2027 | Viewed by 283 | Submission Open

Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging

(This special issue belongs to the Section Cardiology)

The New Frontier in Rheumatoid Arthritis: From Clinical Phenotypes to Precision Medicine

edited by Paula David and Amit Druyan

submission deadline 20 Apr 2027 | Viewed by 191 | Submission Open

Keywords: rheumatoid arthritis; precision medicine; musculoskeletal ultrasound; MRI; difficult-to-treat (D2T) RA; clinical phenotypes

(This special issue belongs to the Section Immunology & Rheumatology)

Innovations in Percutaneous Coronary Intervention

edited by Sachin Kumar and Amit Hooda

submission deadline 20 Apr 2027 | Viewed by 190 | Submission Open

Keywords: percutaneous coronary intervention; intravascular imaging; coronary physiology; complex coronary interventions; calcified coronary lesions; chronic total occlusion; atherectomy; bifurcation PCI; coronary CT angiography

(This special issue belongs to the Section Cardiology)

Displaying special issue 1251-1300 on page 26 of 30.

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