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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plastic and Reconstructive Surgery: Cutting-Edge Expert Perspective
edited by and
submission deadline 20 Aug 2026 | 7 articles | Viewed by 6996 | Submission Open
Keywords: plastic and reconstructive surgery; new perspectives; regeneration; microsurgery; oncoplastic; post bariatric; breast implant
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Hypertension: Clinical Treatment and Management submission deadline 20 Aug 2026 | 5 articles | Viewed by 6838 | Submission Open
Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies
(This special issue belongs to the Section Epidemiology & Public Health)
Advanced Hysteroscopic Technology for Gynecological Disease submission deadline 20 Aug 2026 | 5 articles | Viewed by 6825 | Submission Open
Keywords: hysteroscopy; new technology; therapy; mini-invasive approach; laser; diagnosis; outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Hepatobiliary Surgery: State of the Art and Future Perspectives
edited by and
submission deadline 20 Aug 2026 | 2 articles | Viewed by 6820 | Submission Open
Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Colorectal Surgery: Innovative Techniques and Enhanced Patient Outcomes
edited by Filippo Carannante and Leandro Siragusa
submission deadline 20 Aug 2026 | 4 articles | Viewed by 6670 | Submission Open
Keywords: colorectal surgery; minimally invasive techniques; artificial intelligence; perioperative patient management; translational research in coloproctology
(This special issue belongs to the Section General Surgery)
Diagnosis and Treatment of Cardiovascular Diseases in the Elderly submission deadline 20 Aug 2026 | 6 articles | Viewed by 6452 | Submission Open
Keywords: cardiovascular diseases; elderly population; diagnosis and management; age-related pathophysiology; frailty and cognitive impairment
(This special issue belongs to the Section Geriatric Medicine)
Clinical Translation of Technological Innovations in Diabetes Therapeutics
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 5863 | Submission Open
Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring
(This special issue belongs to the Section Endocrinology & Metabolism)
Management of Congenital Heart Disease (CHD)
edited by Sarah Nordmeyer and Marie Schafstedde
submission deadline 20 Aug 2026 | 6 articles | Viewed by 5527 | Submission Open
Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Kidney Transplantation: State-of-the-Art Knowledge
edited by , Georgios Geropoulos and Kyriakos Psarras
submission deadline 20 Aug 2026 | 3 articles | Viewed by 5462 | Submission Open
Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection
(This special issue belongs to the Section Nephrology & Urology)
Current Concepts and Updates in Eye Diseases
edited by Wiktor Stopyra, and Anna Machalinska
submission deadline 20 Aug 2026 | 4 articles | Viewed by 5192 | Submission Open
Keywords: corneal disease; glaucoma; cataract, uveitis; ocular oncology; retinal disorder; ocular treatment; eye surgery; ocular diagnostics
(This special issue belongs to the Section Ophthalmology)
Rising Star: Advanced Physical Therapy and Expansion
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 5021 | Submission Open
Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach
(This special issue belongs to the Section Clinical Rehabilitation)
Clinics and Management of Allergic and Inflammatory Skin Disorders submission deadline 20 Aug 2026 | 4 articles | Viewed by 4844 | Submission Open
Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management
(This special issue belongs to the Section Dermatology)
New Advances and Clinical Outcomes of Pediatric Endocrinology
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 4802 | Submission Open
Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria
(This special issue belongs to the Section Clinical Pediatrics)
Bariatric Surgery: Challenges and Future Trends
edited by Hugo Santos-Sousa
submission deadline 20 Aug 2026 | 2 articles | Viewed by 4614 | Submission Open
Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures
(This special issue belongs to the Section General Surgery)
Musculoskeletal Pain: Clinical Management Updates submission deadline 20 Aug 2026 | 4 articles | Viewed by 4598 | Submission Open
Keywords: musculoskeletal pain; chronic pain; gait assessment; musculoskeletal disorders; patellofemoral pain
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)
edited by and Georgios Hillas
submission deadline 20 Aug 2026 | 5 articles | Viewed by 4392 | Submission Open
Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging
(This special issue belongs to the Section Respiratory Medicine)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3963 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain submission deadline 20 Aug 2026 | 2 articles | Viewed by 3890 | Submission Open
Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain
(This special issue belongs to the Section Orthopedics)
Myocarditis and Pericarditis: Clinical Advances and Current Challenges submission deadline 20 Aug 2026 | 1 articles | Viewed by 3680 | Submission Open
Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium
(This special issue belongs to the Section Cardiovascular Medicine)
New Clinical Advances in Chronic Asthma—2nd Edition
edited by Vitaliano Nicola Quaranta
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3667 | Submission Open
Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids
(This special issue belongs to the Section Respiratory Medicine)
Surgical Oncology: Clinical Application of Translational Medicine
edited by Domenico Parmeggiani
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3608 | Submission Open
Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research
(This special issue belongs to the Section Oncology)
Clinical Applications of Cardiac Imaging: 2nd Edition
edited by Maria Concetta Pastore
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3536 | Submission Open
Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease
(This special issue belongs to the Section Cardiology)
Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations submission deadline 20 Aug 2026 | 3 articles | Viewed by 3485 | Submission Open
Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain
(This special issue belongs to the Section Clinical Rehabilitation)
Cancer Immunotherapy: Recent Advances and Clinical Challenges
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 3473 | Submission Open
Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms
(This special issue belongs to the Section Oncology)
Breast Cancer: Symptoms, Types, Causes & Treatment
edited by Min-Jeong Cho and Sara Myers
submission deadline 20 Aug 2026 | 2 articles | Viewed by 3097 | Submission Open
Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies
(This special issue belongs to the Section Obstetrics & Gynecology)
Anesthesia and Intensive Care: Clinical Practices and Prospects
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3012 | Submission Open
Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization
(This special issue belongs to the Section Intensive Care)
Rehabilitation and Treatment of Post-COVID-19 Condition submission deadline 20 Aug 2026 | 2 articles | Viewed by 2789 | Submission Open
Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work
(This special issue belongs to the Section Clinical Rehabilitation)
Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction
edited by and Maria Maiello
submission deadline 20 Aug 2026 | 3 articles | Viewed by 2718 | Submission Open
Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health
(This special issue belongs to the Section Cardiovascular Medicine)
Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke submission deadline 20 Aug 2026 | 1 articles | Viewed by 2678 | Submission Open
Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment
(This special issue belongs to the Section Clinical Neurology)
Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition
edited by Tsutomu Yasukawa
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2653 | Submission Open
Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium
(This special issue belongs to the Section Ophthalmology)
Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis
edited by Luigi Carbone and Daniela Pugliese
submission deadline 20 Aug 2026 | 5 articles | Viewed by 2519 | Submission Open
Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies
(This special issue belongs to the Section Intensive Care)
Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2163 | Submission Open
Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)
(This special issue belongs to the Section Intensive Care)
Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives
edited by Gheorghe Tomoaia and Daniel Oltean-Dan
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2093 | Submission Open
Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery
(This special issue belongs to the Section Orthopedics)
Advances in the Management of Cervical Spine Trauma submission deadline 20 Aug 2026 | 3 articles | Viewed by 2029 | Submission Open
Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome
(This special issue belongs to the Section Orthopedics)
Updates on Neuromuscular Diseases
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 1993 | Submission Open
Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics submission deadline 20 Aug 2026 | 3 articles | Viewed by 1993 | Submission Open
Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care
(This special issue belongs to the Section Geriatric Medicine)
New Perspectives and Innovations in Critical Illness submission deadline 20 Aug 2026 | 3 articles | Viewed by 1962 | Submission Open
Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support
(This special issue belongs to the Section Intensive Care)
Endocrine Surgery: Current Treatment and Future Options
edited by Pietro Princi and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1907 | Submission Open
Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation
(This special issue belongs to the Section General Surgery)
Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 1905 | Submission Open
Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment
(This special issue belongs to the Section Clinical Rehabilitation)
From Clinical Diagnosis to Effective Treatment of Cardiomyopathy submission deadline 20 Aug 2026 | 2 articles | Viewed by 1759 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Advances in Trauma and Orthopedic Surgery: 3rd Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 1644 | Submission Open
Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome
(This special issue belongs to the Section Orthopedics)
Advances in Maternal–Fetal Medicine
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1616 | Submission Open
Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Acromegaly
edited by , Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1609 | Submission Open
Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma
(This special issue belongs to the Section Endocrinology & Metabolism)
New Insights into Orthodontic Treatment
edited by Federico Brugnami and Simonetta Meuli
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1542 | Submission Open
Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Refractive Surgery and Intraocular Lens Implantation
edited by Antonio Leccisotti
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1452 | Submission Open
Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik
(This special issue belongs to the Section Ophthalmology)
Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges
edited by Konstantinos Mourouzis
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1366 | Submission Open
Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification
(This special issue belongs to the Section Cardiovascular Medicine)
New Developments and Challenges in Assisted Reproductive Technology
edited by and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1319 | Submission Open
Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging
edited by Katarzyna Nowomiejska
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1316 | Submission Open
Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Clinical Management in Hematologic Oncology
edited by Sunil Lakhwani and José María Raya-Sánchez
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1167 | Submission Open
Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management
(This special issue belongs to the Section Hematology)
Heart Failure and Transplant Cardiology: Latest Advances and Prospects
edited by Monika Budnik
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1147 | Submission Open
Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies
(This special issue belongs to the Section Cardiology)
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