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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Head and Neck Surgery—2nd Edition

edited by

Gábor Dénes Répássy

submission deadline 28 Feb 2026 | Viewed by 32 | Submission Open

Keywords: otorhinolaryngology; head and neck surgery; ear surgery; sinonasal surgery; skull base surgery; salivary gland surgery; thyroid gland surgery; head and neck cancer surgery

(This special issue belongs to the Section General Surgery)

New Advances and Clinical Outcomes of Pediatric Endocrinology

edited by

Gerdi Tuli

submission deadline 28 Feb 2026 | Viewed by 25 | Submission Open

Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria

(This special issue belongs to the Section Clinical Pediatrics)

Emerging Therapies: Clinical Trials and Insights in Psoriasis

edited by

Beata Kowalewska

and Elżbieta Krajewska-Kułak

submission deadline 28 Feb 2026 | Viewed by 21 | Submission Open

Keywords: psoriasis; clinical trials; biomarkers; psychodermatology; treatment; modern therapy; individualized therapy

(This special issue belongs to the Section Dermatology)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Feb 2026 | Viewed by 17 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Tumor Microenvironment—Current Status and Therapeutic Targets

edited by

Rashi Kalra

submission deadline 28 Feb 2026 | Viewed by 12 | Submission Open

Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies

(This special issue belongs to the Section Oncology)

Clinical Therapeutic Advances of Mitral Regurgitation

edited by Angelo Squeri

submission deadline 28 Feb 2026 | Viewed by 7 | Submission Open

Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography

(This special issue belongs to the Section Cardiovascular Medicine)

Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies

edited by

Francesco Colombo

submission deadline 28 Feb 2026 | Submission Open

Keywords: epithelial barrier dysfunction; intestinal microbiota dysbiosis; minimally invasive surgery in IBDs; disease monitoring; perianal disease treatment; surgical complications in IBD; prehabilitation; stoma formation and management; timing of surgery in IBDs; risk stratification for IBD surgery; patient-reported outcomes post-surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Diagnosis and Management of Corneal Diseases

edited by Eirini-Kanella Panagiotopoulou,

Georgios Labiris

and Panagiota Ntonti

submission deadline 10 Mar 2026 | Submission Open

Keywords: corneal imaging; corneal disease diagnosis; corneal therapeutics; regenerative corneal treatments; artificial intelligence in corneal diagnostics; corneal cross-linking; lamellar keratoplasty

(This special issue belongs to the Section Ophthalmology)

Oral Hygiene: Updates and Clinical Progress: 2nd Edition

edited by

Frédéric Denis

submission deadline 15 Mar 2026 | Viewed by 13 | Submission Open

Keywords: periodontal disease; dental caries; plaque control; oral hygiene practices; gingivitis; dental prophylaxis; oral health education

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition

edited by

Luca Giovanella

and

Petra Petranović Ovčariček

submission deadline 15 Mar 2026 | Viewed by 12 | Submission Open

Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism

(This special issue belongs to the Section Endocrinology & Metabolism)

Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets

edited by

Alfredo Caturano

submission deadline 15 Mar 2026 | Viewed by 4 | Submission Open

Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets

(This special issue belongs to the Section Cardiovascular Medicine)

Novel Developments in Dental and Oral Surgery

edited by

Antonio Rapani

Teresa Lombardi

and

Federico Berton

submission deadline 15 Mar 2026 | Submission Open

Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Progress in Clinical Diagnosis and Therapy in Ophthalmology

edited by

Edward Wylegala

submission deadline 16 Mar 2026 | Viewed by 61 | Submission Open

Keywords: ophthalmic imaging; artificial intelligence in ophthalmology; retinal diseases; corneal transplantation; glaucoma diagnostics; ocular therapeutics; personalized medicine; ocular genetics

(This special issue belongs to the Section Ophthalmology)

Clinical Practices of Critical Care in Emergency Medicine

edited by

Gianni Turcato

submission deadline 17 Mar 2026 | Viewed by 4 | Submission Open

Keywords: non-invasiveness; non-ICU critically ill patient; organ replacement versus organ support; prognostic assessment; vasopressors; inotropes; and vasoactive agents; emergency department

(This special issue belongs to the Section Intensive Care)

Neurocritical Care: Clinical Advances and Practice Updates: 2nd Edition

edited by Ali Seifi

submission deadline 18 Mar 2026 | Viewed by 4 | Submission Open

Keywords: traumatic brain injury (TBI); intracerebral hemorrhage (ICH); neurocritical care practice; neurocritical care; neurosurgical innovations; artificial intelligence; medical device and technology innovation in neurocritical care; stroke management; subarachnoid hemorrhage (SAH); status epilepticus

(This special issue belongs to the Section Clinical Neurology)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

submission deadline 20 Mar 2026 | Viewed by 42 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’ s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Mar 2026 | Viewed by 18 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Up-to-Date Research on Nerve Ultrasound

edited by

Hubertus Axer

and Eman A. Tawfik

submission deadline 20 Mar 2026 | Viewed by 17 | Submission Open

Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines

(This special issue belongs to the Section Clinical Neurology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Mar 2026 | Viewed by 17 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Mar 2026 | Viewed by 12 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers

edited by Pablo De Gracia and Héctor E. Soriano Baron

submission deadline 20 Mar 2026 | Viewed by 8 | Submission Open

Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers

(This special issue belongs to the Section Ophthalmology)

New Advances in Clinical Epidemiological Research Methods

edited by

Dorota Sys

and Anna Scholz

submission deadline 20 Mar 2026 | Viewed by 7 | Submission Open

Keywords: clinical epidemiology; research methodology; observational studies; causal inference; real-world data; machine learning; bias control

(This special issue belongs to the Section Clinical Research Methods)

Clinical Advances in Laryngeal Cancer

edited by

Gunnar Wichmann

and

Theresa Wald

submission deadline 20 Mar 2026 | Viewed by 6 | Submission Open

Keywords: head and neck cancer (HNC); laryngeal cancer; larynx organ preservation; immuno-oncology; biomarker; prognostic factor; genetic risk factors; outcome research

(This special issue belongs to the Section Otolaryngology)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 20 Mar 2026 | Viewed by 5 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Obesity and Bariatric Surgery—2nd Edition

edited by Valentin Mocanu and Jerry Dang

submission deadline 20 Mar 2026 | Viewed by 5 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Advances in Maternal–Fetal Medicine: 2nd Edition

edited by

Erich Cosmi

submission deadline 20 Mar 2026 | Viewed by 4 | Submission Open

Keywords: precision medicine; omics; clinical; fetus; Doppler

(This special issue belongs to the Section Obstetrics & Gynecology)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Mar 2026 | Viewed by 3 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Recent Advances in Vitreoretinal Surgery: 2nd Edition

edited by

Lihteh Wu

submission deadline 20 Mar 2026 | Viewed by 1 | Submission Open

Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Emerging Insights into Glaucoma, Cataracts, and Refractive Surgery

edited by

Michele Lanza

submission deadline 20 Mar 2026 | Submission Open

Keywords: trabeculoplasty; MIGS; MIBS; trabeculectomy; IOL; biometry; phacoemulsification; femto-cataract; refractive cataract; excimer laser; PRK; femto; LASIK; SMILE; aberrometry; tomography

(This special issue belongs to the Section Ophthalmology)

Challenges and Opportunities in Prenatal Diagnosis

edited by Diana Massalska and

Julia Bijok

submission deadline 20 Mar 2026 | Submission Open

Keywords: prenatal diagnosis; genetic testing; fetal imaging; fetal therapy; personalized prenatal medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies

edited by Raanan Meyer

submission deadline 20 Mar 2026 | Submission Open

Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Mar 2026 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Field of Radiation Oncology: An Update

edited by

Jack Phan

and

Anna Lee

submission deadline 20 Mar 2026 | Submission Open

Keywords: radiation oncology; image-guided radiotherapy (IGRT); immunotherapy; machine learning; radiation

(This special issue belongs to the Section Oncology)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

, Ana Filipa Beato and

Stephanie Alves

submission deadline 20 Mar 2026 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Advances in Diagnosis and Treatment of Endometriosis

edited by

Arrigo Fruscalzo

and

Anis Feki

submission deadline 20 Mar 2026 | Submission Open

Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone

(This special issue belongs to the Section Obstetrics & Gynecology)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Mar 2026 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Update on Minimally Invasive Gynecologic Surgery

edited by

Greg J. Marchand

submission deadline 20 Mar 2026 | Submission Open

Keywords: minimally invasive gynecologic surgery (MIGS); obstetrics and gynecology; single-port laparoscopy; hysterectomy; robotic surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Neurorehabilitation

edited by

Giuliana Vezzadini

and

Michela Candini

submission deadline 20 Mar 2026 | Submission Open

Keywords: neurorehabilitation; robotics; artificial intelligence; neurodegenerative diseases; Parkinson’ s disease; stroke

(This special issue belongs to the Section Clinical Rehabilitation)

Personalized Medicine and Treatment in Inflammatory Bowel Diseases

edited by Carmen Monica Preda

submission deadline 21 Mar 2026 | Viewed by 6 | Submission Open

Keywords: personalized medicine; inflammatory bowel diseases (IBDs); Crohn’ s disease; ulcerative colitis; biomarkers; pharmacogenomics; microbiome; anti-TNF therapy; precision medicine; machine learning

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Osteosarcoma: New Insights into Diagnosis and Treatment

edited by Lars M. Wagner

submission deadline 25 Mar 2026 | Viewed by 14 | Submission Open

Keywords: osteosarcoma; tyrosine kinase inhibitors; immunotherapy; clinical trial design; intratumoral heterogeneity; liquid biopsy; metastasectomy; deep learning; translational research; targeted therapy

(This special issue belongs to the Section Oncology)

Translational Immunology in Clinical Medicine: From Preclinical Insights to Therapeutic Impact

edited by

Soheil Tavakolpour

submission deadline 25 Mar 2026 | Viewed by 12 | Submission Open

Keywords: translational immunology; autoimmune disease; autoinflammatory disease; immune-mediated diseases; oncology; preclinical models; immune efficacy and safety; mechanism of action; immunotoxicity assessment

(This special issue belongs to the Section Immunology)

Degenerative Cervical Myelopathy and Traumatic Spinal Cord Injury: Recent Advances and Future Directions

edited by Nader Hejrati,

Michael G. Fehlings

and Maryam Seif

submission deadline 28 Mar 2026 | 1 articles | Viewed by 417 | Submission Open

Keywords: degenerative cervical myelopathy; traumatic spinal cord injury; clinical assessment; surgical management; non-operative management; neuroprotective therapies; neuroregenerative therapies; outcome prediction

(This special issue belongs to the Section Clinical Neurology)

Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment

edited by Francesco Melillo

submission deadline 28 Mar 2026 | Viewed by 7 | Submission Open

Keywords: aortic stenosis; mitral stenosis; TAVI

(This special issue belongs to the Section Cardiology)

Management of Female Pelvic Floor Disorders and Incontinence

edited by Luis López Fando

submission deadline 28 Mar 2026 | Submission Open

Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology

(This special issue belongs to the Section Nephrology & Urology)

Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition

edited by

Vera Geraldes

and

Isabel Rocha

submission deadline 31 Mar 2026 | Viewed by 64 | Submission Open

Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms

(This special issue belongs to the Section Cardiology)

JSOPB 2025–2026 Congress Special Issue–Update on Organ Preservation and Transplantation

edited by

Issei Saitoh

and

Takashi Kenmochi

submission deadline 31 Mar 2026 | Viewed by 54 | Submission Open

Keywords: organ preservation; transplantation; pharmacology; engineering; stem cell therapy

(This special issue belongs to the Section General Surgery)

New Insights into Clinical Application of Embolization Techniques

edited by

Bedros Taslakian

and Yan Epelboym

submission deadline 31 Mar 2026 | Viewed by 24 | Submission Open

Keywords: embolization; interventional radiology; musculoskeletal embolization; uterine artery embolization; prostate artery embolization; vascular malformations; catheter-directed therapy

(This special issue belongs to the Section Vascular Medicine)

Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications

edited by

Franz Zehentmayr

submission deadline 31 Mar 2026 | Viewed by 22 | Submission Open

Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation

(This special issue belongs to the Section Oncology)

Acute Trauma and Trauma Care in Orthopedics: 2nd Edition

edited by

Pietro Maniscalco

and

Gianfilippo Caggiari

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: orthopedics; trauma; injury; musculoskeletal; surgery; knee; osteoarthritis; spinal deformity; fracture; joint replacement; hip fractur; fragility fracture; minimally invasive surgery; post-traumatic care and rehabilitation; pain management; emergency assessment

(This special issue belongs to the Section Orthopedics)

Pregnancy and Delivery Complications: Bridging Research and Clinical Practice

edited by

Maria Patricia Roman

, Andrei Mihai Malutan and Răzvan Ciortea

submission deadline 31 Mar 2026 | Submission Open

Keywords: maternal– fetal medicine; obstetric complications; perinatal health; pelvic floor disorders; childbirth perineal trauma; risk stratification; patient-reported outcomes; patient-reported outcome measures

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 1351-1400 on page 28 of 29.

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