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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Research and Insights in Endometriosis
edited by
submission deadline 20 Dec 2025 | Viewed by 166
Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics
(This special issue belongs to the Section Obstetrics & Gynecology)
Advanced Technologies, Concepts, and Topics in Modern Neurosurgery
edited by and Ralf Stroop
submission deadline 20 Dec 2025 | Viewed by 166
Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning
(This special issue belongs to the Section General Surgery)
Advances in Lung Transplantation and Interventional Pulmonology
edited by Anupam Kumar and Frye Laura
submission deadline 20 Dec 2025 | Viewed by 163
Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery
(This special issue belongs to the Section Respiratory Medicine)
Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers submission deadline 20 Dec 2025 | Viewed by 116
Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations in Preeclampsia
edited by Jeffrey M. Denney and
submission deadline 22 Dec 2025 | 4 articles | Viewed by 16742 | Submission Open
Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects
edited by Maria Chiara Maccarone and
submission deadline 22 Dec 2025 | 2 articles | Viewed by 4048 | Submission Open
Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine
(This special issue belongs to the Section Orthopedics)
Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition) submission deadline 22 Dec 2025 | 1 articles | Viewed by 785 | Submission Open
Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 24 Dec 2025 | 2 articles | Viewed by 1168 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Sports Injury: Clinical Prevention and Treatment
edited by , Susana Pulgar and
submission deadline 25 Dec 2025 | 4 articles | Viewed by 26134 | Submission Open
Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV
(This special issue belongs to the Section Sports Medicine)
Skin Diseases: From Diagnosis to Treatment
edited by
submission deadline 25 Dec 2025 | 6 articles | Viewed by 20053 | Submission Open
Keywords: skin; melanoma; NMSC; CTCL; mesenchymal
(This special issue belongs to the Section Dermatology)
Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease
edited by
submission deadline 25 Dec 2025 | 6 articles | Viewed by 14647 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography submission deadline 25 Dec 2025 | 3 articles | Viewed by 12318 | Submission Open
Keywords: computed tomography (CT); spectral CT; dual-energy CT; dual-source spectral CT; dual-layer spectral CT; pho-ton-counting CT; photon-counting detector CT; spectral photon-counting CT; artificial intelligence; radiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Targeted Treatment of Kidney Stones
edited by Carmen Gonzalez-Enguita and
submission deadline 25 Dec 2025 | 4 articles | Viewed by 11401 | Submission Open
Keywords: shockwave lithotripsy; ureteroscopy; percutaneous nephrolithotomy; laser lithotripsy; minimally invasive techniques; stone recurrence prevention
(This special issue belongs to the Section Nephrology & Urology)
Thyroid Cancer: Clinical Diagnosis and Treatment
edited by Alfred A. Simental
submission deadline 25 Dec 2025 | 5 articles | Viewed by 11243 | Submission Open
Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery
(This special issue belongs to the Section Oncology)
Clinical Epidemiology in Chronic Kidney Disease
edited by and Claudia Torino
submission deadline 25 Dec 2025 | 7 articles | Viewed by 10816 | Submission Open
Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure
(This special issue belongs to the Section Nephrology & Urology)
New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias
edited by
submission deadline 25 Dec 2025 | 5 articles | Viewed by 10208 | Submission Open
Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block
(This special issue belongs to the Section Cardiology)
Anterior Cruciate Ligament (ACL): Innovations in Clinical Management
edited by Xaver Feichtinger, and Georg Brandl
submission deadline 25 Dec 2025 | 4 articles | Viewed by 9491 | Submission Open
Keywords: ACL; graft choice; ACL repair; ALL; tibial slope
(This special issue belongs to the Section Orthopedics)
Innovations in Maxillofacial Surgery
edited by , and Ignacio Navarro Cuéllar
submission deadline 25 Dec 2025 | 5 articles | Viewed by 9023 | Submission Open
Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Inflammatory and Infectious Skin Diseases (Second Edition)
edited by , Astrid Herzum and Paolo Romita
submission deadline 25 Dec 2025 | 4 articles | Viewed by 8473 | Submission Open
Keywords: atopic dermatitis; eczematous diseases; inflammatory skin diseases; chronic skin diseases; human herpesvirus; roseola syphilitica; psoriasis
(This special issue belongs to the Section Dermatology)
Pulmonary Embolism: Clinical Advances and Future Opportunities
edited by James Horowitz
submission deadline 25 Dec 2025 | 4 articles | Viewed by 6053 | Submission Open
Keywords: pulmonary embolism; risk stratification; pulmonary embolism response teams; high risk PE; massive PE; intermediate risk PE; sub massive PE; catheter directed thrombolysis; catheter thrombectomy; catheter directed embolectomy; extra corporeal membrane oxygenation
(This special issue belongs to the Section Respiratory Medicine)
Recent Research Progress in Pediatric Orthopedic Surgery
edited by and Madeleine Willegger
submission deadline 25 Dec 2025 | 4 articles | Viewed by 5888 | Submission Open
Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand
(This special issue belongs to the Section Clinical Pediatrics)
Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases
edited by Vincenzo Davide Palumbo
submission deadline 25 Dec 2025 | 3 articles | Viewed by 5134 | Submission Open
Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Radiation Therapy for Cancers submission deadline 25 Dec 2025 | 3 articles | Viewed by 4230 | Submission Open
Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Insights in Skin Tumors: From Pathogenesis to Therapy
edited by Loredana Ungureanu and Simona C. Şenilǎ
submission deadline 25 Dec 2025 | 3 articles | Viewed by 2920 | Submission Open
Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology
(This special issue belongs to the Section Dermatology)
Advances in Anterior Segment Surgery: Second Edition
edited by
submission deadline 25 Dec 2025 | 2 articles | Viewed by 2003 | Submission Open
Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry
(This special issue belongs to the Section Ophthalmology)
Innovations and Future Directions in Valvular Heart Disease: Imaging, Technology, and Translational Research
edited by , Muhammed Gerçek and Felix Rudolph
submission deadline 25 Dec 2025 | 3 articles | Viewed by 1583 | Submission Open
Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis; minimally invasive surgery; concomitant valve disease
(This special issue belongs to the Section Cardiology)
Advances and Innovations in Hand Surgery
edited by , Jason Wink and Anthony Archual
submission deadline 25 Dec 2025 | 2 articles | Viewed by 967 | Submission Open
Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Psychological Pain and Suicidal Behavior: Clinical Implications
edited by Adrián Alacreu-Crespo
submission deadline 25 Dec 2025 | 2 articles | Viewed by 771 | Submission Open
Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes
(This special issue belongs to the Section Mental Health)
Kidney Health Under Microscope
edited by
submission deadline 25 Dec 2025 | Viewed by 314 | Submission Open
Keywords: complications; IgA nephropathy; glomerulonephritis; atypical haemolytic uraemic syndrome; systemic vasculitis; lupus nephritis; mineral bone disease; anaemia; xenotransplantation; nephrolithiasis
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Imaging Techniques in Heart Failure Care
edited by David Snipelisky
submission deadline 25 Dec 2025 | Viewed by 294 | Submission Open
Keywords: heart failure; advanced imaging; cardiac imaging; echocardiography; cardiomyopathies
(This special issue belongs to the Section Cardiology)
IgA Nephropathy: Clinical Updates and Prospects
edited by
submission deadline 25 Dec 2025 | Viewed by 154 | Submission Open
Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Rehabilitation: Clinical Challenges and New Insights
edited by Melissa Tracy
submission deadline 26 Dec 2025 | 3 articles | Viewed by 10673 | Submission Open
Keywords: cardiovascular disease; cardiac rehabilitation; atrial fibrillation
(This special issue belongs to the Section Cardiology)
Current Clinical Treatments and Challenges for Cardiovascular Diseases
edited by Georgios Bouras and
submission deadline 26 Dec 2025 | 4 articles | Viewed by 7716 | Submission Open
Keywords: heart failure; coronary artery disease; atrial fibrillation; cardiomyopathies; hypertension
(This special issue belongs to the Section Cardiovascular Medicine)
New Advances in Extracorporeal Life Support (ECLS)
edited by Robertas Stasys Samalavičius, and
submission deadline 26 Dec 2025 | 2 articles | Viewed by 5511 | Submission Open
Keywords: extracorporeal life support (ECLS); extracorporeal membrane oxygenation (ECMO); innovations in ECLS; respiratory failure; cardiogenic shock; eCPR
(This special issue belongs to the Section Emergency Medicine)
Current Clinical Advances and Challenges for Endourology submission deadline 26 Dec 2025 | 2 articles | Viewed by 2033 | Submission Open
Keywords: urolithiasis; upper tract urothelial carcinoma; benign prostatic hyperplasia; minimally invasive surgical therapies
(This special issue belongs to the Section Nephrology & Urology)
Multifactorial Causation and Therapies of Myopia: 2nd Edition submission deadline 26 Dec 2025 | 1 articles | Viewed by 1103 | Submission Open
Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
Clinical Updates on Metabolic and Bariatric Surgery
edited by Maria-Jose Barahona
submission deadline 27 Dec 2025 | 1 articles | Viewed by 1448 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; weight loss; obesity treatment; metabolic disorders
(This special issue belongs to the Section General Surgery)
Atrial Fibrillation Rhythm Management: Outcomes, Innovations, and Future Directions
edited by Roberto Scacciavillani and Gemma Pelargonio
submission deadline 28 Dec 2025 | 6 articles | Viewed by 6271 | Submission Open
Keywords: atrial fibrillation; catheter ablation; radiofrequency; cryoablation; pulsed field ablation; cardioneuroablation; left bundle branch area pacing
(This special issue belongs to the Section Cardiology)
Lung Transplantation: Current Strategies and Future Directions
edited by Omer Senbaklavaci and György Lang
submission deadline 28 Dec 2025 | 1 articles | Viewed by 1760 | Submission Open
Keywords: lung transplantation; graft optimization; immunosuppression; artificial lung; xenotransplantation; end-stage lung disease; donor lung preservation; chronic lung allograft dysfunction
(This special issue belongs to the Section Respiratory Medicine)
Imaging and Molecular Biomarkers: The New Approach to Degenerative Retinal Diseases submission deadline 28 Dec 2025 | 2 articles | Viewed by 1117 | Submission Open
Keywords: ophthalmology; degenerative retinal diseases; imaging biomarkers; multimodal imaging; OCT; OCT angiography; molecular biomarkers; precision medicine; translational ophthalmic research
(This special issue belongs to the Section Ophthalmology)
Managements of Venous Thromboembolism submission deadline 29 Dec 2025 | 4 articles | Viewed by 2901 | Submission Open
Keywords: venous thromboembolism; deep vein thrombosis; pulmonary embolism; anticoagulation therapy; direct oral anticoagulants; risk stratification; bleeding risk; artificial intelligence; personalized medicine
(This special issue belongs to the Section Vascular Medicine)
Pediatric Neurosurgery: Clinical Advances in Diagnostics and Perioperative Management
edited by Kara Leigh Krajewski and Ulrich-Wilhelm Thomale
submission deadline 29 Dec 2025 | 1 articles | Viewed by 1713 | Submission Open
Keywords: rapid sequence MRI; intraoperative MRI; perioperative management; neurocritical care; patient selection; M&M conferences; surgical team; rehabilitation
(This special issue belongs to the Section Clinical Pediatrics)
Current Concepts and Clinical Application of Echocardiography
edited by
submission deadline 29 Dec 2025 | Viewed by 177 | Submission Open
Keywords: echocardiography; clinical echocardiography; advanced echocardiography; cardiovascular disease; clinical cardiology
(This special issue belongs to the Section Cardiology)
Treatment of Atopic Dermatitis
edited by and Ricardo Ruíz-Villaverde
submission deadline 30 Dec 2025 | 7 articles | Viewed by 22989 | Submission Open
Keywords: atopic dermatitis; eczema; topical treatment; systemic treatment; biological therapy; JAK inhibitor; antipruritic treatment
(This special issue belongs to the Section Dermatology)
Chronic Pain: Non-Pharmacological Treatments and Rehabilitation Strategies
edited by Matteo Ponzano
submission deadline 30 Dec 2025 | 8 articles | Viewed by 19549 | Submission Open
Keywords: pain; neuropathies; musculoskeletal health; biopsychosocial management; physical therapy; cognitive behavioral therapies
(This special issue belongs to the Section Clinical Rehabilitation)
Current Challenges in Inflammatory Bowel Diseases submission deadline 30 Dec 2025 | 4 articles | Viewed by 9942 | Submission Open
Keywords: ulcerative colitis; Chron’ s disease; inflammatory bowel disease; colitis-associated cancer; novel pharmaceutics
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The State of Breast Reconstruction: From Surgical Methods to Patient-Reported Outcomes
edited by Geoffroy C. Sisk
submission deadline 30 Dec 2025 | 2 articles | Viewed by 6669 | Submission Open
Keywords: breast reconstruction; implant based; autologous tissue; oncoplastic; breast cancer reconstruction; patient-reported outcomes; acellular dermal matrix; prepectoral; lymphedema; microsurgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Recent Advances in Glaucoma Management
edited by Bogomil Voykov
submission deadline 30 Dec 2025 | 3 articles | Viewed by 5062 | Submission Open
Keywords: glaucoma; MIGS; microinvasive glaucoma surgery; quality of life; sustained-release drugs; wound healing modula-tion; intraocular pressure; intraocular pressure-lowering medication; microstent-supported bleb surgery; MIBS; neuroprotection
(This special issue belongs to the Section Ophthalmology)
Augmented and Artificial Intelligence in Ophthalmology
edited by Tina Felfeli, Edsel B. Ing, David Jose Mathew and Michael Balas
submission deadline 30 Dec 2025 | 2 articles | Viewed by 2904 | Submission Open
Keywords: artificial intelligence; ophthalmology; eye health; vision; teleophthalmology
(This special issue belongs to the Section Ophthalmology)
Inflammatory Bowel Disease: From Diagnosis to Treatment—2nd Edition
edited by Laura Maria Minordi and Daniela Pugliese
submission deadline 30 Dec 2025 | 3 articles | Viewed by 2592 | Submission Open
Keywords: Crohn’ s disease; ulcerative colitis; imaging; endoscopy; complications; advanced therapies; surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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