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Special Issues
Current Clinical Advances and Challenges for Endourology
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Current Clinical Advances and Challenges for Endourology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 340

Special Issue Editors

Dr. Carlo Giulioni

E-Mail Website
Guest Editor
Department of Urology, Casa di Cura Villa Igea, 60127 Ancona, Italy
Interests: urologic oncology; minimally invasive surgery; urolithiasis; benign prostate hyperplasia; male fertility
Dr. Daniele Castellani

E-Mail Website
Guest Editor
Urology Unit, Azienda Ospedaliero-Universitaria delle Marche, Università Politecnica delle Marche, 60121 Ancona, Italy
Interests: urologic oncology; minimally invasive surgery; urolithiasis; benign prostate hyperplasia; male fertility
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the recent few decades, endourology has undergone a significant transformation, shifting from traditional open surgeries to minimally invasive techniques that have markedly improved patient outcomes. This evolution has been propelled by continuous technological advancements and a deepening understanding of urinary tract diseases.

This Special Issue seeks to showcase the latest clinical advancements in endourology, offering a platform for experts to present and discuss emerging techniques, technologies, and therapeutic strategies. Our objective is to provide a comprehensive overview of the current challenges and potential future directions in endourological practice.

We invite submissions that delve into the exploration of new frontiers in endourology, including innovative surgical techniques and cutting-edge treatments for complex urological conditions. Contributions that critically analyze existing practices and propose enhancements are especially welcome.

The scope of this Special Issue covers the entire spectrum of endourology, with a particular emphasis on managing patients with clinical conditions, which may elevate intraoperative and postoperative risks. Submissions should address both the successes and challenges encountered in the clinical application of endourological techniques.

Dr. Carlo Giulioni
Dr. Daniele Castellani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urolithiasis
  • upper tract urothelial carcinoma
  • benign prostatic hyperplasia
  • minimally invasive surgical therapies

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Published Papers (1 paper)

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Research

13 pages, 659 KiB  
Article
The Implementation of Trifecta Score to Assess the Quality of Holmium Laser Enucleation of the Prostate in Elderly Patients: An Analysis of Perioperative and Functional Outcomes and the Impact of Age
by Carlo Giulioni, Matteo Tallè, Alessio Papaveri, Francesco Mengoni, Roberto Orciani, Savio Domenico Pandolfo, Ciro Imbimbo, Felice Crocetto, Valentina Maurizi, Vineet Gauhar and Angelo Cafarelli
J. Clin. Med. 2025, 14(10), 3410; https://doi.org/10.3390/jcm14103410 - 13 May 2025
Viewed by 143
Abstract
Background: The aim of this study was to assess the efficacy and safety of Holmium Laser Enucleation of the Prostate (HoLEP) in the treatment of symptomatic benign prostatic hyperplasia (BPH) in elderly patients using the Trifecta Score, based on a 1-year follow-up. [...] Read more.
Background: The aim of this study was to assess the efficacy and safety of Holmium Laser Enucleation of the Prostate (HoLEP) in the treatment of symptomatic benign prostatic hyperplasia (BPH) in elderly patients using the Trifecta Score, based on a 1-year follow-up. Methods: We conducted a retrospective analysis of patients with BPH who underwent HoLEP at our institution between January 2016 and December 2022. The patients were divided into two groups: Group 1: patients aged ≥75 years, Group 2: patients aged below 74 years. The Trifecta Score achievement rates were then evaluated. Logistic regression analyses were performed to examine the impact of age on Trifecta parameters and to assess factors associated with urinary incontinence. Results: Overall, 981 participants were enrolled, with 490 in Group 1 and 491 in Group 2. Operative characteristics were similar between groups, though Group 1 had a longer time to catheter removal. At the 3-month follow-up, Group 1 had a higher IPSS and lower Qmax compared to Group 2, while there were no significant differences in functional outcomes by one year. In terms of postoperative morbidities, Group 1 exhibited a higher rate of blood transfusion. The Trifecta Score was similar between Groups 1 and 2 (63.5% vs. 68.8%, respectively, p = 0.08), and no parameter of that score exhibited a negative correlation with age. Conclusions: HoLEP demonstrates comparable functional outcomes to those observed in younger cohorts after one year. Overall, the Trifecta Score appears to be a valuable tool for this assessment. Nevertheless, incorporating an assessment of postoperative urinary continence and 1-year postoperative Qmax could enhance the system’s validity. Full article
(This article belongs to the Special Issue Current Clinical Advances and Challenges for Endourology)
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