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Advances in Anterior Segment Surgery: Second Edition
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Advances in Anterior Segment Surgery: Second Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 25 December 2025 | Viewed by 65

Special Issue Editor

Dr. Mayank A. Nanavaty

E-Mail Website
Guest Editor
Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, UK
Interests: laser refractive surgery; refractive lens exchange; complex cataract surgeries; vision correction surgeries; corneal transplants; keratoconus management
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to invite you to contribute to the Special Issue entitled “Advances in Anterior Segment Surgery: 2nd Edition”. This is one new volume; we published five papers in the first volume. For more details, please visit: https://www.mdpi.com/journal/jcm/special_issues/DHTHDD997W.

The aim of this Special Issue is to highlight the current themes in modern laser-, corneal-, and lens-based refractive surgery. This issue will feature three articles from world-renowned refractive surgeons on the latest trends and themes relating to refractive surgery.

We will be delighted if you are able to submit a full-length article or review on a topic of your choice in refractive, corneal, and cataract surgery. The possible areas of interest for this issue are lenticule-based surgery, surface ablations, blended vision treatments with laser refractive surgery, corneal inlay procedures, presbyopia management with monovision laser vision correction, refractive lens exchange, premium presbyopia-correcting intraocular lenses, refractive solutions for keratoconics, complex cataract surgery, biometry, cataract surgery outcomes, modern lamellar corneal transplants, etc.

We will be grateful if you can let us know whether this is something you are interested in contributing to.

Dr. Mayank A. Nanavaty
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lenticule-based surgery
  • surface ablations
  • blended vision treatments with laser refractive surgery
  • corneal inlay procedures
  • presbyopia management with monovision laser vision correction
  • refractive lens exchange
  • premium presbyopia-correcting intraocular lens
  • refractive solutions for keratoconics
  • cataract surgery
  • corneal transplant
  • biometry

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Published Papers (1 paper)

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Research

12 pages, 239 KiB  
Article
Ten Years’ Experience Using Proxymetacaine Hydrochloride 0.5% for Postoperative Pain Control in Epithelium-Off Corneal Crosslinking
by Mohamed Gamal Elghobaier, Issac Levy and Mayank A. Nanavaty
J. Clin. Med. 2025, 14(13), 4692; https://doi.org/10.3390/jcm14134692 - 2 Jul 2025
Viewed by 1
Abstract
Background/Objectives: To evaluate the efficacy and safety of using the preservative-free topical proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) to control postoperative pain after epithelium-off corneal crosslinking (CXL) for keratoconus. Methods: This is an observational study [...] Read more.
Background/Objectives: To evaluate the efficacy and safety of using the preservative-free topical proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) to control postoperative pain after epithelium-off corneal crosslinking (CXL) for keratoconus. Methods: This is an observational study of patients with mild to severe keratoconus who have undergone epithelium-off CXL. CXL was completed by applying dextran-free riboflavin (0.1%) for 10 min (Vibex Rapid; Avedro, Inc.), followed by continuous UV-A light (Avedro KXL system; Avedro, Inc.) for 30 min at an intensity of 3 mW/cm2 and an energy of 5.4 J/cm2. All patients were prescribed postoperative proxymetacaine hydrochloride PRN with an allowed frequency of up to eight times per 24 h for the first 3 days to control postoperative pain. Patients were reviewed at 1–2 weeks postoperatively for a comprehensive examination, including assessment of delayed corneal healing, removal of the bandage contact lens, and recording of subjective symptoms. Results: There were 223 eyes of 180 patients with a mean age of 24.9 ± 8.6 years (range: 13–38 years). Male patients were 72%. At their planned first postoperative visit, we found no corneal healing abnormalities, such as persistent epithelial defects, epithelial irregularities, or early postoperative stromal haze, in any patient. All patients subjectively reported that proxymetacaine drops helped them to control postoperative pain, particularly in the first 48 h. Conclusions: None of the patients reported pain after 3 days of using proxymetacaine drops up to eight times a day for the first 3 days. It appears to be a safe and effective solution to control postoperative pain without any complications. Full article
(This article belongs to the Special Issue Advances in Anterior Segment Surgery: Second Edition)
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