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Special Issues
Recent Advances in Glaucoma Management
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Recent Advances in Glaucoma Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1610

Special Issue Editor

Dr. Bogomil Voykov

E-Mail Website
Guest Editor
Department of Ophthalmology, University Eye Hospital, Eberhard Karls University Tuebingen, Tuebingen, Germany
Interests: glaucoma; glaucoma surgery; MIGS; intraocular pressure

Special Issue Information

Dear Colleagues,

We have seen remarkable innovations in glaucoma treatment and management over the last ten years. The way we treat glaucoma is continuously changing and improving with the introduction of novel medications, laser procedures, and surgical methods. Patients’ quality of life has never been put so much at the center of our glaucoma management as today. In this Special Issue, we would like to highlight some of the recent advances in glaucoma treatment and management that have the potential to change our daily clinical practice.

Dr. Bogomil Voykov
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • glaucoma
  • MIGS
  • microinvasive glaucoma surgery
  • quality of life
  • sustained-release drugs
  • wound healing modula-tion
  • intraocular pressure
  • intraocular pressure-lowering medication
  • microstent-supported bleb surgery
  • MIBS
  • neuroprotection

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 1447 KiB  
Article
Two-Year Results of XEN Gel Stent Implantation for Pseudoexfoliative Glaucoma in Phakic versus Pseudophakic Eyes
by Emil Nasyrov, David A. Merle, Caroline J. Gassel, Daniel A. Wenzel and Bogomil Voykov
J. Clin. Med. 2024, 13(14), 4066; https://doi.org/10.3390/jcm13144066 - 11 Jul 2024
Cited by 1 | Viewed by 1157
Abstract
Objectives: To investigate whether phakia affects the outcome of XEN-45 gel stent implantation in the treatment of pseudoexfoliative glaucoma (PXG). Methods: A retrospective, comparative cohort study of 30 phakic and 55 pseudophakic PXG patients who received the XEN-45 gel stent at [...] Read more.
Objectives: To investigate whether phakia affects the outcome of XEN-45 gel stent implantation in the treatment of pseudoexfoliative glaucoma (PXG). Methods: A retrospective, comparative cohort study of 30 phakic and 55 pseudophakic PXG patients who received the XEN-45 gel stent at a tertiary centre. The primary outcome measure was two-year success defined as a ≥20% lowering of intraocular pressure (IOP) and a target IOP of 6–21 mmHg. Success was complete without and qualified irrespective of antiglaucoma medication use. Further glaucoma surgery other than needling was regarded as a failure. The secondary outcome measures included changes in IOP, revision and complication rates. Results: The complete two-year success rates were 70% and 59% in the phakic and pseudophakic groups, respectively (p = 0.75, log-rank test), and the qualified rates were 80% and 72%, respectively (p = 0.89). The median IOP reduction from baseline was 54% in phakic, and 46% in pseudophakic eyes. While needling rates were similar, the incidence of early incisional bleb revisions was significantly higher in the phakic eyes (13% vs. 0% within 3 months; p = 0.0098, chi-square). Increasing after a year, significantly more pseudophakic eyes failed due to secondary glaucoma surgery (16% vs. 0%; p = 0.0191). Conclusions: The XEN-45 gel stent offers equally effective IOP control for both phakic and pseudophakic patients. However, the onset of bleb revisions and the necessity for secondary glaucoma surgery differed significantly between the groups. Full article
(This article belongs to the Special Issue Recent Advances in Glaucoma Management)
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