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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skin Disease and Inflammation
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 5534 | Submission Open
Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea
(This special issue belongs to the Section Dermatology)
Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges
edited by , and Athanasia Korda
submission deadline 20 Mar 2026 | 2 articles | Viewed by 5135 | Submission Open
Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy
(This special issue belongs to the Section Otolaryngology)
Advanced Therapy for Heart Failure and Other Combined Diseases
edited by Gori Mauro and Marco Marini
submission deadline 20 Mar 2026 | 5 articles | Viewed by 5065 | Submission Open
Keywords: heart failure with reduced and preserved ejection fraction; advanced heart failure; inotropes; acute heart failure; GDMT
(This special issue belongs to the Section Cardiology)
Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition
edited by Botond Csiky
submission deadline 20 Mar 2026 | 2 articles | Viewed by 4980 | Submission Open
Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease
(This special issue belongs to the Section Nephrology & Urology)
Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS) submission deadline 20 Mar 2026 | 3 articles | Viewed by 4597 | Submission Open
Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk
(This special issue belongs to the Section Respiratory Medicine)
The Role of Scleral Lenses in the Management of Eye Disease
edited by Cherie B. Nau
submission deadline 20 Mar 2026 | 1 articles | Viewed by 4462 | Submission Open
Keywords: scleral lenses; corneal irregularity; corneal disease; dry eye disease; irregular astigmatism; keratoconus; meibomian gland dysfunction; midday fogging
(This special issue belongs to the Section Ophthalmology)
Advanced Approaches in Hip and Knee Arthroplasty
edited by Filippo Randelli and
submission deadline 20 Mar 2026 | 4 articles | Viewed by 4333 | Submission Open
Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty
(This special issue belongs to the Section Orthopedics)
Psoriasis in Focus: Current Research, Treatments, and Future Directions
edited by and Josep Riera-Monroig
submission deadline 20 Mar 2026 | 4 articles | Viewed by 4287 | Submission Open
Keywords: psoriasis; biologic therapies; immunopathogenesis; precision medicine; comorbidities in psoriasis; psoriatic arthritis; phototherapy; topical treatments; systemic therapies
(This special issue belongs to the Section Dermatology)
Clinical and Surgical Updates on Bariatric Surgery submission deadline 20 Mar 2026 | 2 articles | Viewed by 4146 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD
(This special issue belongs to the Section General Surgery)
Clinical Advances in Kidney Transplantation submission deadline 20 Mar 2026 | 3 articles | Viewed by 3937 | Submission Open
Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation
(This special issue belongs to the Section Nephrology & Urology)
Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy submission deadline 20 Mar 2026 | 2 articles | Viewed by 3782 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology
(This special issue belongs to the Section Cardiology)
Acute Pancreatitis and Its Complications: Current Diagnostics and Management submission deadline 20 Mar 2026 | 3 articles | Viewed by 3551 | Submission Open
Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Thoracic Surgery: State of the Art and Future Directions
edited by and
submission deadline 20 Mar 2026 | 5 articles | Viewed by 3444 | Submission Open
Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum
(This special issue belongs to the Section Respiratory Medicine)
Advances in Breast Reconstruction: New Technologies Improving Clinical Outcomes
edited by Luigi Antonio Valdatta
submission deadline 20 Mar 2026 | 3 articles | Viewed by 3147 | Submission Open
Keywords: breast reconstruction; acellular dermal matrix (ADM); artificial intelligence in surgery; advanced prostheses; breast malformation correction; 3D printing in reconstruction; robotic-assisted breast surgery; regenerative surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Challenges and Opportunities in Prenatal Diagnosis
edited by Diana Massalska and
submission deadline 20 Mar 2026 | 2 articles | Viewed by 2957 | Submission Open
Keywords: prenatal diagnosis; genetic testing; fetal imaging; fetal therapy; personalized prenatal medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Artificial Intelligence, Computer Modeling and Technology: Clinical Changing Practice in Reconstructive Surgery submission deadline 20 Mar 2026 | 2 articles | Viewed by 2799 | Submission Open
Keywords: reconstructive surgery; plastic surgery; breast surgery; breast reconstruction; oncologic surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries
edited by Nili Steinberg
submission deadline 20 Mar 2026 | 3 articles | Viewed by 2753 | Submission Open
Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent
(This special issue belongs to the Section Sports Medicine)
Management of Inflammatory Bowel Disease: A Multidisciplinary Perspective submission deadline 20 Mar 2026 | 2 articles | Viewed by 2696 | Submission Open
Keywords: inflammatory bowel disease management; Crohn's disease; ulcerative colitis; patient-centered care; multidisciplinary management; personalized treatment
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Progress in Pediatric Orthopedics and Pediatric Spine Surgery
edited by
submission deadline 20 Mar 2026 | 3 articles | Viewed by 2452 | Submission Open
Keywords: pediatric spine; scoliosis; clubfoot; flatfoot; developmental dysplasia of the hip; rare diseases
(This special issue belongs to the Section Clinical Pediatrics)
Hypertension: Clinical Treatment and Management submission deadline 20 Mar 2026 | 2 articles | Viewed by 2344 | Submission Open
Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies
(This special issue belongs to the Section Epidemiology & Public Health)
Dual-Energy and Spectral CT in Clinical Practice: 2nd Edition
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 2008 | Submission Open
Keywords: dual-energy CT; spectral CT; photon counting CT; oncology; bone marrow edema; prosthesis; liver; pancreas; lung; kidney; adrenal; brain; abdomen; cardiac; coronary arteries; arthritis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers
edited by Pablo De Gracia and Héctor E. Soriano Baron
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1932 | Submission Open
Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers
(This special issue belongs to the Section Ophthalmology)
Lung Transplantation: Clinical Advances and Practice Updates
edited by Milton Saute
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1890 | Submission Open
Keywords: lung transplantation; respiratory failure; thoracic surgery; cardiothoracic surgery; solid organ transplantation; immunosuppression; lung cancer
(This special issue belongs to the Section Respiratory Medicine)
New Advances in Systemic Lupus Erythematosus (SLE)
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1802 | Submission Open
Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life
(This special issue belongs to the Section Immunology & Rheumatology)
Diagnosis and Surgical Treatment for Colorectal Cancer
edited by Nidal Issa, Wisam Khoury and Rachel Gingold-Belfer
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1767 | Submission Open
Keywords: colorectal cancer; laparoscopy; colonoscopy; colectomy; diagnosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Systemic Autoimmune Disorder with Pulmonary Involvement: Novel Insights from Underlying Mechanisms of Drug Development and Intervention
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1668 | Submission Open
Keywords: rheumatic diseases; pulmonary involvement; connective tissue disorders; systemic autoimmune disorders (SARDs); diagnosis; innovative treatments
(This special issue belongs to the Section Respiratory Medicine)
Clinical Therapy in Dementia and Related Diseases
edited by
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1649 | Submission Open
Keywords: dementia; aging society; disease-modifying therapies (DMT); early diagnosis; lifestyle interventions; multimorbidity management; non-pharmacological treatments; personalized medicine; quality of life (QOL); digital health technologies
(This special issue belongs to the Section Mental Health)
Advances in Clinical Exercise for Health
edited by and Joana Ribeiro
submission deadline 20 Mar 2026 | 3 articles | Viewed by 1604 | Submission Open
Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology
(This special issue belongs to the Section Sports Medicine)
Thrombosis and Haemostasis: Clinical Advances
edited by Hui Yin Lim
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1360 | Submission Open
Keywords: venous thrombosis; biomarkers; bleeding; direct oral anticoagulants; pulmonary embolism; factor XI inhibitors; factor XII inhibitors; endovascular treatment
(This special issue belongs to the Section Vascular Medicine)
Clinical Developments of Oral and Maxillofacial Surgery submission deadline 20 Mar 2026 | 1 articles | Viewed by 1323 | Submission Open
Keywords: oral surgery; maxillofacial surgery; bone resorption; implant surgery; oral rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Acute Hypoxemic Respiratory Failure: Progress, Challenges and Future submission deadline 20 Mar 2026 | 2 articles | Viewed by 1290 | Submission Open
Keywords: ARDS; artificial intelligence; mechanical ventilation; non-invasive ventilation; lung imaging
(This special issue belongs to the Section Intensive Care)
Clinical Diagnosis and Therapeutic Approaches for Acute and Chronic Coronary Syndromes
edited by Rocco Antonio Montone
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1273 | Submission Open
Keywords: coronary artery disease; clinical diagnosis; therapeutic approaches; atherosclerosis; risk factors; percutaneous cor-onary intervention; acute coronary syndrome; MINOCA; INOCA
(This special issue belongs to the Section Cardiology)
Pancreatic Surgery: Clinical Practices and Challenges
edited by Guido Alsfasser and
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1168 | Submission Open
Keywords: prognostic variables; surgical technique; outcome; timing of surgery; perioperative strategies; pancreatic cancer; pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Perspectives in Cardiac Imaging: How to See the Unseen
edited by and Wanda Acampa
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1138 | Submission Open
Keywords: cardiac imaging; MPI; PET; SPECT; CCTA; MR; CAD; heart failure; cardiac sarcoidosis; cardiac amyloidosis; valvular disease; artificial intelligence
(This special issue belongs to the Section Cardiology)
Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies
edited by Raanan Meyer
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1112 | Submission Open
Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Challenges and New Perspectives in Liver Transplantation
edited by and
submission deadline 20 Mar 2026 | 2 articles | Viewed by 1107 | Submission Open
Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cognitive Impairment, Dementia and Depression in Older Adults
edited by Seong Jae Kim and Ilhan Choo
submission deadline 20 Mar 2026 | 1 articles | Viewed by 1099 | Submission Open
Keywords: cognitive impairment; dementia; depression; Parkinson’ s disease; artificial intelligence (AI); predictive modeling
(This special issue belongs to the Section Geriatric Medicine)
Liquid Biopsies in Oral Cancer: Advances and New Perspectives submission deadline 20 Mar 2026 | 1 articles | Viewed by 1030 | Submission Open
Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Fresh Insights in Skin Disease
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 926 | Submission Open
Keywords: inflammatory dermatoses; dermoscopy; melanoma; autoimmune skin conditions; psoriasis; skin cancers; skin syndromes
(This special issue belongs to the Section Dermatology)
Minimally Invasive Surgery: Challenges and Solutions in Clinical Practice
edited by and Alessia Fassari
submission deadline 20 Mar 2026 | 1 articles | Viewed by 816 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes
(This special issue belongs to the Section General Surgery)
Esophageal and Upper Interventional Endoscopy and Surgery: Latest Advances and Prospects
edited by Giulia Gibiino
submission deadline 20 Mar 2026 | 1 articles | Viewed by 770 | Submission Open
Keywords: gastric preneoplastic and neoplastic lesions; endoscopic submucosal dissection (ESD); endoscopic full-thickness resection (EFTR); subepithelial upper GI lesions; duodenal adenomas; esophageal stenting
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Obesity and Bariatric Surgery—2nd Edition
edited by Valentin Mocanu and Jerry Dang
submission deadline 20 Mar 2026 | 1 articles | Viewed by 770 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment
(This special issue belongs to the Section Endocrinology & Metabolism)
New Advances in Clinical Epidemiological Research Methods
edited by and Anna Scholz
submission deadline 20 Mar 2026 | 1 articles | Viewed by 750 | Submission Open
Keywords: clinical epidemiology; research methodology; observational studies; causal inference; real-world data; machine learning; bias control
(This special issue belongs to the Section Clinical Research Methods)
Clinical Advances in Autism Management submission deadline 20 Mar 2026 | 1 articles | Viewed by 530 | Submission Open
Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization
(This special issue belongs to the Section Mental Health)
Innovations in Emergency and Critical Care Medicine
edited by Yoshiaki Iwashita
submission deadline 20 Mar 2026 | Viewed by 506 | Submission Open
Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography
(This special issue belongs to the Section Intensive Care)
Latest Advances in Minimally Invasive Spine Surgery
edited by Fabian Sommer and
submission deadline 20 Mar 2026 | 1 articles | Viewed by 476 | Submission Open
Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics; augmented reality; artificial intelligence; etc.); degenerative spine; patient safety in MISS
(This special issue belongs to the Section Clinical Neurology)
Challenges and Innovations in Thrombosis and Haemostasis
edited by Vasiliki Danilatou and Fotios I. Girtovitis
submission deadline 20 Mar 2026 | Viewed by 404 | Submission Open
Keywords: air pollution and thrombosis; antiphospholipid syndrome; antithrombotic therapy; arterial thrombosis; artificial intelligence in thrombosis and haemostasis; biology of arterial thrombosis; biomarkers in thrombosis and haemostasis; cancer-associated thrombosis; clinical decision support; current concepts and novel targets for antiplatelet treatments; digital health in heamostasis and thrombosis; endotheliopathy and thrombosis; ethical challenges in thrombosis care; hemophilia and von willebrand disease; innovative therapies in thrombosis and haemostasis; pediatric thrombosis; platelet biology and function: new concepts and clinical perspectives; rare blood disorders; thrombophilia; thrombosis and hemostasis guidelines; thrombosis in pregnancy; thrombo-inflammation; trauma-induced coagulopathy; venous thromboembolism
(This special issue belongs to the Section Vascular Medicine)
Recent Advances in Head and Neck Surgery
edited by Lisa Catarzi, and
submission deadline 20 Mar 2026 | Viewed by 345 | Submission Open
Keywords: head and neck surgery; reconstructive surgery; microsurgical reconstruction; new technologies; computer-assisted surgery; surgical innovation; post-operative care
(This special issue belongs to the Section Otolaryngology)
Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood
edited by Kamila Chęcińska and
submission deadline 20 Mar 2026 | 1 articles | Viewed by 329 | Submission Open
Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Treatment Strategies for Prostate Cancer: An Update submission deadline 20 Mar 2026 | 1 articles | Viewed by 223 | Submission Open
Keywords: prostate cancer; robotic surgery; uro-oncology; focal therapy; single-port; radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
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