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Diagnosis and Surgical Treatment for Colorectal Cancer
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Diagnosis and Surgical Treatment for Colorectal Cancer

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 25 September 2025 | Viewed by 492

Special Issue Editors

Dr. Nidal Issa

E-Mail Website
Guest Editor
1. School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
2. Department of Surgery, Rabin Medical Center, Hasharon Hospital, Petach Tikva 49372, Israel
Interests: rectal tumors; colon cancer; transanal endoscopic microsurgery; laparoscopy
Dr. Wisam Khoury

E-Mail Website
Guest Editor
1. Colorectal Surgery Unit, Department Surgery A, Carmel Medical Center, Haifa, Israel
2. The Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
Interests: rectal tumors; colon cancer; robotics; laparoscopy
Dr. Rachel Gingold-Belfer

E-Mail Website
Guest Editor
1. School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
2. Department of Gastroenterology, Rabin Medical Center, Petach Tikva , Israel
Interests: colorectal disease; colonoscopy; recatl polyps
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the comprehensive management of colorectal cancer, emphasizing diagnosis and surgical treatment. In diagnosis, it covers various screening modalities including fecal immunochemical testing, fecal occult blood testing, and stool DNA testing. Colonoscopy is the gold standard assessment method, with emphasis on advanced imaging techniques and artificial intelligence-assisted detection. Imaging modalities for metastatic assessment and staging, as well as various biomarkers and genetic signatures, are covered in this Special Issue.

For surgical treatment, we detail different approaches, including open surgery, laparoscopic, and robotic procedures. Special procedures for different stages, ranging from early-stage local excision to extensive surgery for metastatic disease, are covered. Perioperative management encompasses pre- and postoperative interventions, as well as strategies for preventing and managing complications.

We welcome submissions addressing these aspects of colorectal cancer care, aiming to advance our understanding of this topic and improve patient outcomes.

Dr. Nidal Issa
Dr. Wisam Khoury
Dr. Rachel Gingold-Belfer
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • colorectal cancer
  • laparoscopy
  • colonoscopy
  • colectomy
  • diagnosis

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Published Papers (1 paper)

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Research

8 pages, 187 KiB  
Article
Ultrasound as a First-Line Modality for Acute Colonic Diverticulitis: A Prospective Comparison with CT
by Gil N. Bachar, Eli Atar, Moran Dahan, Haim Neiman, Tamar Gurvitz, Issa Nidal and Selma Gabrieli
J. Clin. Med. 2025, 14(7), 2510; https://doi.org/10.3390/jcm14072510 - 7 Apr 2025
Viewed by 364
Abstract
Objectives: We aimed to compare the accuracy of ultrasound and computed tomography (CT) for the diagnosis of patients with suspected acute diverticulitis and to determine if ultrasound might serve as the primary tool for this purpose in the emergency department. Methods: A double-blind [...] Read more.
Objectives: We aimed to compare the accuracy of ultrasound and computed tomography (CT) for the diagnosis of patients with suspected acute diverticulitis and to determine if ultrasound might serve as the primary tool for this purpose in the emergency department. Methods: A double-blind prospective study design was used. The study group included 142 consecutive patients with clinically suspected diverticulitis admitted to the emergency department of a tertiary medical center in 2016–2019. All underwent first ultrasound examination followed by abdominal CT. The final diagnosis was interpreted independently by an expert radiologist in a blinded fashion. Imaging data were compared with final diagnosis and we analyzed the findings against the medical, clinical, and laboratory data. Results: The final diagnosis was colonic diverticulitis in 98 patients. Sensitivity was 93.8% for ultrasound and 100% for CT; corresponding specificity rates were 86.7% and 100%. Agreement between the modalities was excellent (kappa = 0.81). CT demonstrated complicated diverticulosis in 18 patients: 8 pericolic abscesses, 9 micro-perforations, and 1 fistula. Ultrasound missed one abscess and five micro-perforations; however, all were small and were treated conservatively. Twenty-three patients were found to have an acute abdominal condition other than diverticulitis; sensitivity in these cases was 60.8% for ultrasound and 91.3% for CT. In 21 patients, the diagnosis was unknown. Conclusions: Ultrasound has similar sensitivity and specificity to CT for the diagnosis of acute colonic diverticulitis. We believe ultrasound may serve as the initial imaging modality in the emergency department, with CT reserved for large abscesses or inconclusive ultrasound findings. Full article
(This article belongs to the Special Issue Diagnosis and Surgical Treatment for Colorectal Cancer)
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