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New Progress in Pediatric Orthopedics and Pediatric Spine Surgery
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New Progress in Pediatric Orthopedics and Pediatric Spine Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 743

Special Issue Editor

Dr. Barbara Jasiewicz

E-Mail Website
Guest Editor
Department of Orthopedics and Rehabilitation, Jagiellonian University Medical College, Balzera 15, 34-500 Zakopane, Poland
Interests: pediatric orthopedics and spine; neurosurgery; orthopedics and rehabilitation

Special Issue Information

Dear Colleagues,

Recent years have seen rapid development in pediatric orthopedics—in many aspects, it is almost a revolution. We are now proficient in treating clubfoot, developmental hip dysplasia, and scoliosis. However, there are still problems to be solved, such as the optimal treatment of early-onset scoliosis. The issue of achieving the most normal spinal growth in children with its abnormalities and deformities remains the subject of ongoing research and analysis. On the other hand, we are also facing new challenges: the development of new pharmacological treatments for certain systemic conditions (spinal muscular atrophy, Rett syndrome) offers hope for improvement in the health of these patients, but the consequence is the emergence of other/new orthopedic problems in these patients.

We welcome original and review papers connected with all aspects of pediatric orthopedics, including, but not limited to, scoliosis (idiopathic, congenital, neuromuscular), foot and hip disorders, gait problems, post-traumatic sequelae, and bone and joint tumors.

Dr. Barbara Jasiewicz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric spine
  • scoliosis
  • clubfoot
  • flatfoot
  • developmental dysplasia of the hip
  • rare diseases

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Published Papers (2 papers)

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Research

10 pages, 1700 KiB  
Article
Serial Casting for Early-Onset Scoliosis
by Jakub Adamczyk, Slawomir Duda, Wojciech Kacki, Barbara Jasiewicz and Tomasz Potaczek
J. Clin. Med. 2025, 14(12), 4329; https://doi.org/10.3390/jcm14124329 - 18 Jun 2025
Viewed by 229
Abstract
Background: Early-onset scoliosis (EOS) is a severe spinal deformity that can compromise thoracic development and pulmonary function if left untreated. While Mehta casting is widely used to manage deformity non-surgically in young children, its effects on spinal and thoracic growth remain underexplored. [...] Read more.
Background: Early-onset scoliosis (EOS) is a severe spinal deformity that can compromise thoracic development and pulmonary function if left untreated. While Mehta casting is widely used to manage deformity non-surgically in young children, its effects on spinal and thoracic growth remain underexplored. Methods: In this retrospective case series, 15 children with EOS underwent serial elongation–derotation–flexion (EDF) Mehta casting. Radiographic assessments were performed pre-treatment, post-casting, and at follow-up, including measurements of Cobb angle, rib–vertebral angle difference (RVAD), Th1–Th12 spinal length, coronal chest width (CCW), and space available for lung (SAL). Growth rates were estimated based on the duration of treatment. Correlation analyses were conducted to examine associations between baseline deformity and structural outcomes. Results: Serial casting reduced the mean Cobb angle by 22.2° and RVAD by 15.5°. During treatment, measurable increases were observed in Th1–Th12 length (mean: 2.93 cm), CCW (1.12 cm), SAL-L (2.60 cm), and SAL-R (2.98 cm). Estimated annual growth was significantly greater in children with lower initial Cobb and RVAD values. In contrast, total casting duration showed no consistent correlation with growth outcomes. Conclusions: Mehta casting is effective not only in correcting spinal deformity but also in supporting thoracic and axial growth in children with EOS. Early application in flexible, less severe curves may optimize structural outcomes and preserve thoracic development during early growth. Full article
(This article belongs to the Special Issue New Progress in Pediatric Orthopedics and Pediatric Spine Surgery)
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9 pages, 187 KiB  
Article
Surgical Access for Intrathecal Therapy in Spinal Muscular Atrophy with Spinal Fusion: Long-Term Outcomes of Lumbar Laminectomy
by Tomasz Potaczek, Sławomir Duda and Jakub Adamczyk
J. Clin. Med. 2025, 14(12), 4280; https://doi.org/10.3390/jcm14124280 - 16 Jun 2025
Viewed by 296
Abstract
Background/Objectives: Spinal muscular atrophy (SMA) is a neuromuscular disorder frequently associated with progressive scoliosis requiring posterior spinal fusion (PSF). While Nusinersen offers significant clinical benefit, its intrathecal administration is challenging in patients with extensive spinal instrumentation and solid fusion. This study aimed to [...] Read more.
Background/Objectives: Spinal muscular atrophy (SMA) is a neuromuscular disorder frequently associated with progressive scoliosis requiring posterior spinal fusion (PSF). While Nusinersen offers significant clinical benefit, its intrathecal administration is challenging in patients with extensive spinal instrumentation and solid fusion. This study aimed to evaluate the safety, feasibility, and patient acceptance of lumbar laminectomy as a method to restore intrathecal access for repeated Nusinersen delivery in this population. Methods: A retrospective review was conducted in eleven patients with SMA who underwent lumbar laminectomy following prior PSF and confirmed radiographic fusion. Surgical data, injection outcomes, and patient-reported experiences were collected. A structured questionnaire assessed technical success, imaging requirements, sedation, functional response, and satisfaction. Results: Nine out of eleven patients (81.8%) successfully initiated intrathecal Nusinersen therapy through the laminectomy window, receiving a mean of 11.7 injections (range: 10–14). Imaging guidance was used in five cases; three required sedation or anesthesia. Intraoperative dural tears occurred in three patients and were managed without complications. Eight out of nine treated patients reported subjective motor improvement and expressed willingness to undergo the procedure again. No hardware revisions or major adverse events were observed during a mean follow-up of 48.8 months. Conclusions: Lumbar laminectomy is a viable and well-tolerated technique to establish intrathecal access in SMA patients with prior PSF. This approach enables sustained drug delivery and may remain clinically relevant as new intrathecal therapies emerge. Full article
(This article belongs to the Special Issue New Progress in Pediatric Orthopedics and Pediatric Spine Surgery)
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