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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Topoisomerase Inhibitors: Future Perspectives and Challenges

edited by

Ben Bax

and Mark Mitton-Fry

submission deadline 30 Jul 2025 | 3 articles | Viewed by 4650 | Submission Open

Keywords: antibiotic; topoisomerase; inhibitor; anticancer; resistance; safety

(This special issue belongs to the Section Molecular Pharmacology)

Adsorption Materials and Adsorption Behavior: 3rd Edition

edited by

Jun Wang

submission deadline 30 Jul 2025 | 4 articles | Viewed by 4241 | Submission Open

Keywords: adsorption; adsorption materials; adsorption behavior; adsorption mechanisms; adsorption thermodynamics and kinetics; resource extraction; pollutant removal; separation

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Bone Biomaterials Research and 3D Spheroid Culture Systems in Osteogenesis

edited by

Chawon Yun

submission deadline 30 Jul 2025 | 1 articles | Viewed by 3727 | Submission Open

Keywords: osteogenic differentiation; 3D culture; bone regeneration; toxicological and pharmacological assessment; bone homeostasis; bone materials

(This special issue belongs to the Section Materials Science)

Protein Methyltransferases in Human Health and Diseases

edited by

Byron Baron

submission deadline 30 Jul 2025 | 1 articles | Viewed by 3113 | Submission Open

Keywords: lysine and arginine methylation; mass spectrometry; PTM cross talk; functional proteomics; cancer; neurological disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism and Treatment of Allergic Asthma

edited by

Francesco Menzella

and Marcello Cottini

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2697 | Submission Open

Keywords: allergic asthma; epithelial barrier damage; protease allergen; type 2 inflammation

(This special issue belongs to the Section Molecular Immunology)

Antiviral Drugs Discovery

edited by

Dongwei Kang

submission deadline 30 Jul 2025 | 2 articles | Viewed by 2582 | Submission Open

Keywords: antiviral agents; organic synthesis and medicinal chemistry; biological activity; drug design and computational chemistry; drug discovery and development

(This special issue belongs to the Section Molecular Pharmacology)

Pathogenicity and Antibiotic Resistance of Helicobacter pylori

edited by

Paweł Krzyżek

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2523 | Submission Open

Keywords: Helicobacter pylori; antibiotic resistance; antibiotic tolerance; point mutations; efflux pumps; biofilm formation; coccoid forms; membrane vesicles; virulence factors

(This special issue belongs to the Section Molecular Microbiology)

Emerging Roles for Serotonin in Regulating Metabolism

edited by

Giuseppe Bruschetta

and

Patrizia Licata

submission deadline 30 Jul 2025 | 2 articles | Viewed by 2355 | Submission Open

Keywords: serotonin; cortisol; phospholipids; glycosaminoglycans; oxidative stress; veterinary anesthesia and analgesia

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Current Insights into Nucleic Acids

edited by

David Stephen Pisetsky

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2274 | Submission Open

Keywords: nucleic acids; DNA; RNA; genome; gene function; gene regulation; gene structure

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Advances Related to Bone Regeneration

edited by

Gianluigi Pasta

and

Virginie Sottile

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2101 | Submission Open

Keywords: bone regeneration; bone extracellular matrix; regenerative medicine; biomaterials

(This special issue belongs to the Section Molecular Biology)

Dietary Components in the Brain–Gut Axis: Exploring Nutrigenetic and Microbiome Interactions

edited by

Piotr Dobrowolski

submission deadline 30 Jul 2025 | 1 articles | Viewed by 2011 | Submission Open

Keywords: dietary components; carbohydrates; proteins; fats; fatty acids; vitamins; minerals; brain– gut axis; nutrigenetics; microbiome interactions; neurodegenerative disorders; metabolic pathways

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Glycans in Immune Regulation

edited by Senlian Hong

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1836 | Submission Open

Keywords: glycoimmunology; glycotherapy; vaccines; glycan synthesis; immune tolerance

(This special issue belongs to the Section Molecular Immunology)

Advances in Design, Synthesis and Applications of Peptide Nucleic Acid

edited by

Maria Moccia

, Concetta Avitabile and

Annalisa Masi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 1530 | Submission Open

Keywords: PNA; nucleic acid analog; molecular design; synthesis; delivery system; therapeutics; diagnostic

(This special issue belongs to the Section Molecular Biology)

Molecular and Structural Research Advances in Model Plants (Second Edition)

edited by

Ioannis-Dimosthenis Adamakis

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1407 | Submission Open

Keywords: A. thaliana; plant biology; model organisms; plant models; non-model plant models

(This special issue belongs to the Section Molecular Plant Sciences)

Plant–Microbe Interactions: 2nd Edition

edited by Jian Jin

submission deadline 30 Jul 2025 | 2 articles | Viewed by 1166 | Submission Open

Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Cytokines in Health and Diseases

edited by Hung-Jen Liu

submission deadline 30 Jul 2025 | 3 articles | Viewed by 1114 | Submission Open

Keywords: cytokines; immune regulation; disease management; signaling pathways; translational research; clinical applications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Focus on Gastrointestinal Diseases: Inflammation, 3rd Edition

edited by

Marcello Candelli

submission deadline 30 Jul 2025 | Viewed by 1069 | Submission Open

Keywords: signal transduction; receptor signaling; infection and inflammation; protein interaction; tumor biology; growth factors; cytokines; cell death and differentiation; inflammation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Role of Autoimmunity in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

edited by Yang Mao-Draayer

submission deadline 30 Jul 2025 | 1 articles | Viewed by 968 | Submission Open

Keywords: multiple sclerosis (MS); neuromyelitis optica spectrum disorder (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); immunomodulatory; neuroprotection; neuroregeneration; biomarker; imaging

(This special issue belongs to the Section Molecular Neurobiology)

Artificial Intelligence: Applications in the Field of Immune-Mediated Inflammatory Diseases and Onco-Hematology

edited by

Giuseppe Murdaca

and

Sebastiano Gangemi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 917 | Submission Open

Keywords: artificial intelligence; machine learning; immune-mediated diseases; cancers; hematological ma-lignancies

(This special issue belongs to the Section Molecular Immunology)

Food-Derived Bioactive Peptides

edited by

Fidel Toldrá

and

Leticia Mora

submission deadline 30 Jul 2025 | 2 articles | Viewed by 707 | Submission Open

Keywords: peptides identification; peptides characterization; functional foods; biological activity; peptidomics; proteomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Molecular Mechanisms of Bacterial Resistance and Antibiotic Therapy

edited by

Xinyi Yang

submission deadline 30 Jul 2025 | 2 articles | Viewed by 625 | Submission Open

Keywords: bacterial resistance; antibiotics; antimicrobials; “ superbugs” ; clinical strains; laboratory induced-bacteria; antimicrobial peptides; antimicrobial combinations; hybrid antibiotics; repurposing drugs; anti-virulence agents; immune modulators; toxin neutralizers

(This special issue belongs to the Section Molecular Microbiology)

The Molecular Network, Key Biomarkers, and Therapeutic Targets in Colorectal Cancer

edited by

Katharina M. Robertson

submission deadline 30 Jul 2025 | 1 articles | Viewed by 608 | Submission Open

Keywords: inflammation; metabolism; tumor-associated macrophages; tumor microenvironment; early-onset colorectal cancer; colorectal neoplasms; obesity; immunotherapy; epigenetics; cytokines; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hyperelastic Structures

edited by

Hossein Bakhshi Khaniki

and

Mergen Ghayesh

submission deadline 30 Jul 2025 | Viewed by 576 | Submission Open

Keywords: hyperelastic structures; biological properties; molecular properties; nonlinear elasticity; soft structures; material modeling

(This special issue belongs to the Section Materials Science)

Molecular Diagnostic and Treatment Methods in Socially Significant Diseases in Urology

edited by

Elenko Popov

submission deadline 30 Jul 2025 | Viewed by 549 | Submission Open

Keywords: prostate cancer; bladder cancer; renal-cell cancer; risk stratification; urolithiasis; chronic UTIs; BPH; clinical decision-making

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Protein Kinase in Disease, 2nd Edition

edited by

Manae Suzuki Kurokawa

submission deadline 30 Jul 2025 | 1 articles | Viewed by 489 | Submission Open

Keywords: protein kinases; phosphorylation; cancers; inflammatory diseases; protein kinase inhibitors; anticancer drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Energy Metabolism and Obesity: 2nd Edition

edited by

Po-Shiuan Hsieh

submission deadline 30 Jul 2025 | Viewed by 468 | Submission Open

Keywords: energy metabolism; obesity; insulin resistance; glucose and lipid metabolism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Radiation Resistance in Extremophile Bacteria: Unraveling the Molecular Mysteries

edited by

Sathiyaraj Srinivasan

submission deadline 30 Jul 2025 | Viewed by 459 | Submission Open

Keywords: extremophiles; radiation resistance; genome analysis; RNAseq; proteome studies; comparative analysis; molecular mechanisms; genetic adaptation; metabolic shifts; evolutionary insights; eukaryotic resistance

(This special issue belongs to the Section Molecular Microbiology)

Crop Stress Biology and Molecular Breeding: 5th Edition

edited by

Youxiong Que

submission deadline 30 Jul 2025 | 1 articles | Viewed by 450 | Submission Open

Keywords: biotic and abiotic stress; variety improvement; crop stress biology; molecular breeding; biological basis; signal transduction pathway; agronomic traits; excellent germplasm

(This special issue belongs to the Section Molecular Plant Sciences)

Diabetic Retinopathy—Innovation in Diagnosis and Treatment

edited by

Peter Koulen

submission deadline 30 Jul 2025 | Viewed by 434 | Submission Open

Keywords: diabetes mellitus; diabetic macular edema; diagnostics; drug development; neovascularization; neurodegeneration; neuroprotection; retina; therapeutics; vascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cirrhosis: From Molecular Mechanisms to Therapeutic Strategies

edited by

Hongqun Liu

submission deadline 30 Jul 2025 | 1 articles | Viewed by 397 | Submission Open

Keywords: liver; fibrogenesis; cirrhosis; portal hypertension; complications; molecular mechanisms; pathway; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Applications of Gold Nanoparticles in Cancer Theranostics

edited by John Chetley Ford and

Junwei Shi

submission deadline 30 Jul 2025 | Viewed by 361 | Submission Open

Keywords: gold nanoparticles (AuNPs); multifunctional nanoplatform; targeted cancer therapy; drug delivery; theranostics

(This special issue belongs to the Section Materials Science)

Macro- and Micronutrients in Health and Diseases

edited by

Karolina Orywal

and Mariusz Gryko

submission deadline 30 Jul 2025 | 1 articles | Viewed by 349 | Submission Open

Keywords: macronutrients; micronutrients; vitamins; macrominerals; trace elements; cancer; obesity; cardiovascular diseases; diabetes; osteoporosis; immune disorders; neurodegenerative diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Dynamics Simulations of Protein Structures

edited by Alfonso Trezza

submission deadline 30 Jul 2025 | 1 articles | Viewed by 345 | Submission Open

Keywords: molecular dynamics simulations; protein structure analysis; computational methods in structural biology; bioinformatics and drug discovery; protein– ligand interactions

(This special issue belongs to the Section Molecular Biophysics)

Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 30 Jul 2025 | Viewed by 332 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone– immune interface

(This special issue belongs to the Section Molecular Immunology)

Neurological Disorders: From Molecular Mechanisms to Nanomedicine

edited by

Aruna Sharma

submission deadline 30 Jul 2025 | Viewed by 317 | Submission Open

Keywords: stroke; brain and spinal cord trauma; Alzheimer’ s disease; Parkinson’ s disease; nanodrug formulation; stem cells; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Sepsis and Septic Shock: From Molecular Mechanisms to Novel Therapies—2nd Edition

edited by

Markus A. Weigand

and Michael Adamzik

submission deadline 30 Jul 2025 | Viewed by 309 | Submission Open

Keywords: sepsis; septic shock; mechanistic insight; epigenetics; immunometabolism; biomarkers; therapy approach; stratification; precision diagnostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autoimmune Diseases: From Pathogenesis to Treatment and Prognostic Markers

edited by Alessandra Bettiol

submission deadline 30 Jul 2025 | Viewed by 286 | Submission Open

Keywords: autoimmune diseases; inflammation; immunity; pathogenesis; immunosuppressants; biologics; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms Linking Obesity to Atherosclerosis Pathogenesis

edited by

Weibin Shi

submission deadline 30 Jul 2025 | 1 articles | Viewed by 248 | Submission Open

Keywords: obesity; overweight; atherosclerosis; coronary artery disease; obesity paradox; body mass index; visceral fat

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology and Diagnosis on Biliary and Pancreatic Cancers

edited by Francesco Vasuri and Luca Saragoni

submission deadline 30 Jul 2025 | Viewed by 240 | Submission Open

Keywords: biliary cancer; pancreatic cancer; histological diagnoses; cytological diagnoses; chromosome aneuploidy; specific genetic mutations

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Obesity: From Pathogenesis to Therapeutic Targets

edited by Omar Al Massadi, Mar Quiñones and

Luisa Maria Seoane

submission deadline 30 Jul 2025 | Viewed by 224 | Submission Open

Keywords: obesity; energy balance; type 2 diabetes; liver disease; adipose tissue; brain

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms in Kidney Disease

edited by

Tzong-Shyuan Lee

submission deadline 30 Jul 2025 | Viewed by 194 | Submission Open

Keywords: kidney disease; inflammation; redox; senescence; cell death; fibrosis; signaling pathway; uremic syndrome; cardiorenal syndrome; gut– kidney axis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases: 3rd Edition

edited by

Kyriacos N. Felekkis

and

Christos Papaneophytou

submission deadline 30 Jul 2025 | Viewed by 159 | Submission Open

Keywords: miRNA; gene expression regulation; diagnosis; prognosis; therapy; biomarkers

(This special issue belongs to the Section Biochemistry)

Parkinson’s Disease and Related Diseases: Mechanisms, Genetic Factors and Treatments

edited by

Stergios Boussios

submission deadline 30 Jul 2025 | Viewed by 159 | Submission Open

Keywords: Parkinson’ s disease; neurodegenerative disorders; α -synuclein aggregation; neuroinflammation; gene therapy; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Artificial Intelligence in Nano- and Bio-Technology Systems: Focus on Molecular Research

edited by

Abbas Amini

submission deadline 30 Jul 2025 | Viewed by 158 | Submission Open

Keywords: artificial intelligence; nanotechnology; biotechnology; medicine; energy systems; blockchain

(This special issue belongs to the Section Molecular Nanoscience)

Protein Design and Engineering in Biochemistry

edited by Om Prakash Narayan

submission deadline 30 Jul 2025 | Viewed by 149 | Submission Open

Keywords: protein engineering; molecular biology; biochemical tools; computational protein design; directed evolution; CRISPR/Cas9; synthetic biology; biomaterials; protein therapeutics; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Cerebrovascular Diseases: Mediators of the Capillary No-Reflow Phenomenon After Acute Ischemic Stroke

edited by Ákos Menyhárt

submission deadline 30 Jul 2025 | Viewed by 136 | Submission Open

Keywords: capillary; acute ischemic stroke; cerebrovascular; no-reflow

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Bioactive Compounds in Human Health and Disease: 3rd Edition

edited by

Guan-Jhong Huang

submission deadline 30 Jul 2025 | Viewed by 135 | Submission Open

Keywords: cancer; inflammation; cardiovascular diseases; plants; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Green Chemical Pesticide Design, Synthesis and Evaluation

edited by Ranfeng Sun

submission deadline 30 Jul 2025 | Viewed by 124 | Submission Open

Keywords: green pesticides; natural products; action mechanism of pesticides; synthesis

(This special issue belongs to the Section Biochemistry)

Elucidating How Chondrocytes Maintain Cartilage Stability

edited by James A. Martin

submission deadline 30 Jul 2025 | Viewed by 124 | Submission Open

Keywords: chondrocytes; articular cartilage; chondrogenesis; osteoarthritis; mechano-transduction; aging; extracellular matrix

(This special issue belongs to the Section Molecular Biology)

Research Progress and Therapeutic Targets of Chronic Kidney Disease

edited by

Stefanos Roumeliotis

submission deadline 30 Jul 2025 | Viewed by 123 | Submission Open

Keywords: blood pressure; cardiovascular disease; chronic kidney disease; diabetes; hypertension; inflammation; oxidative stress; sodium glucose transporter-2; vascular calcification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1351-1400 on page 28 of 69.

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