Molecular Mechanisms of Obesity: From Pathogenesis to Therapeutic Targets
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 July 2025 | Viewed by 803
Special Issue Editors
Interests: obesity; leptin; metabolic syndrome; adiposity
Interests: hypertension; atherosclerosis; insulin resistance; biochemistry; neuroscience; metabolism; food chemistry; metabolic diseases; antioxidants; blood pressure
Interests: nutrition; molecular biology; metabolism; insulin resistance; metabolic diseases; glucose; lipid metabolism; abdominal obesity; nutritional and metabolic diseases; body composition
Special Issue Information
Dear Colleagues,
Obesity is one of the most significant challenges in 21st century public health, and its study has become essential in understanding the complex interactions between genetic, metabolic, social, and environmental factors contributing to its development. In this regard, metabolic processes play a very important role in the development and maintenance of obesity, a condition that is characterized by both an increase in body fat and a profound reconfiguration of energy metabolism. These processes, which include feeding behavior, energy expenditure, locomotor activity, thermoregulation, lipid and glucose metabolism, and hormonal regulation, among others, help us to understand how obesity is perpetuated in different physiological and environmental scenarios. Obesity is currently a globally popular research topic, mainly due to the development of a new generation of drugs based on GLP-1 agonists; however, it is crucial we continue researching obesity to explore the underlying mechanisms that link it to metabolic disorders, and to open up new avenues for even more effective and personalized treatments. Therefore, this Special Issue welcomes original papers and reviews addressing molecular mechanisms that regulate the different pathologies associated with obesity.
Dr. Omar Al Massadi
Dr. Mar Quiñones
Dr. Luisa Maria Seoane
Guest Editors
Manuscript Submission Information
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Keywords
- obesity
- energy balance
- type 2 diabetes
- liver disease
- adipose tissue
- brain
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