Molecular Advances Related to Bone Regeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 July 2025 | Viewed by 2115
Special Issue Editors
Interests: orthopedic surgery; regenerative medicine; rare diseases
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative medicine; stem cells; biomaterials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bone is a dynamic tissue and the molecular mechanisms underlying its remodeling and regeneration are numerous. In orthopedic and maxillofacial surgery, bone tissue regeneration remains a major challenge. Bone defects can be caused by several adverse events (trauma, cancer, infections, congenital diseases or abnormal skeletal development). Several factors involved in bone regeneration process are able to regulate signaling cascades modifying cellular responses such as differentiation and proliferation. Particular interest is focused on the characteristics of bone extracellular matrix and the pathways related to its synthesis.
Nevertheless, there are still many aspects and new pathways to be clarified that could open new perspectives to new therapies aimed at regulating and stimulating bone regeneration.
Moreover, bone regeneration has to be considered part of regenerative medicine, with studies of new biomaterials and effects of physical stimuli such as electomagnetic waves and gravity on cell biology opening new therapeutic perspectives.
Dr. Gianluigi Pasta
Dr. Virginie Sottile
Guest Editors
Manuscript Submission Information
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Keywords
- bone regeneration
- bone extracellular matrix
- regenerative medicine
- biomaterials
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