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Focus on Gastrointestinal Diseases 3.0: Inflammation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 355

Special Issue Editor

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Guest Editor
Emergency Anesthesiological and Reanimation Sciences, Fondazione Policlinico Universitario A. Gemelli, 00168 Roma, Italy
Interests: short stay unit; infection, sepsis; trauma; syncope; pulmonary embolism; inflammatory bowel disease; gastroenteritis; gastrointestinal bleeding; diverticulitis
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Special Issue Information

Dear Colleagues,

Gastrointestinal diseases are common, multifactorial pathologies related to specific genetic, infectious, environmental, and host factors. Understanding the molecular mechanisms underlying the interaction between these factors is critical to understanding the pathophysiology of gastrointestinal diseases and developing new therapies. These are extremely common diseases in the general population that impose high costs on healthcare systems around the world. The emerging role of the intestinal microbiome and local and general immune factors is transforming our understanding of gastrointestinal diseases. The identification of the molecular mechanisms involved in their development has also led to significant advances in the therapeutic field over the past 20 years. The use of biologic drugs that have altered the natural history of inflammatory bowel disease is a clear example. The molecular characterization of the interactions between external pathogens such as Helicobacter pylori and the host may also help to unravel the mechanisms that trigger inflammatory processes in the mucosa, as well as mutations that may predispose an individual to the occurrence of gastrointestinal cancer.

Since the first and second volumes of the Special Issue "Focus on Gastrointestinal Diseases" were successful, we are reopening this Issue in the International Journal of Molecular Sciences (ISSN 1422-0067, IF 6.208, JCR Category Q1). For this third Special Issue, we invite all interested researchers to contribute original research articles or literature reviews on all aspects related to the molecular mechanisms involved in the pathologies of the gastrointestinal system, with a particular focus on, but not limited to, inflammatory intestinal, pancreatic, and gastric diseases. Furthermore, manuscripts with a particular focus on inflammation will be highly welcomed.

https://www.mdpi.com/iournal/iims/Special Issues/FGD

https://www.mdpi.com/iournal/iims/Special Issues/FGD 2022

Dr. Marcello Candelli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • signal transduction
  • receptor signaling
  • infection and inflammation
  • protein interaction
  • tumor biology
  • growth factors
  • cytokines
  • cell death and differentiation
  • inflammation

Published Papers

This special issue is now open for submission.
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