Cerebrovascular Diseases: Mediators of the Capillary No-Reflow Phenomenon After Acute Ischemic Stroke
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 July 2025 | Viewed by 784
Special Issue Editor
2. Department of Cell Biology and Molecular Medicine, Albert Szent-Györgyi Medical School and Faculty of Science and Informatics, University of Szeged, Szeged, Hungary
Interests: theoretical medicine
Special Issue Information
Dear Colleagues,
The capillary no-reflow phenomenon refers to the inadequate cerebral perfusion that develops despite successful recanalization in the AIS therapy. Even though futile reperfusion is often associated with an unfavorable clinical diagnosis, our understanding of the underlying mechanisms remains limited. The scope of our Special Issue is to address the latest observations and opinions on the mechanisms behind the capillary no-reflow phenomenon after acute ischemic stroke (AIS). We aim to summarize (i) the already known and (ii) suspected mediators of microvascular constriction in the sub-acute phase of AIS. We will focus on the roles of cell specific prostaglandins, eicosatetraenoic acids and vasoactive ions in the development of the capillary no-reflow.
Dr. Ákos Menyhárt
Guest Editor
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Keywords
- capillary
- acute ischemic stroke
- cerebrovascular
- no-reflow
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