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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bio-Nano Interactions—3rd Edition

edited by

Massimiliano Magro

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2384 | Submission Open

Keywords: nanoparticles; proteins; smart nanomaterial surfaces; selective protein binding; nanomaterials; abiotic material; biological systems; bio-inspired inorganic materials and DNA nanotechnologies

(This special issue belongs to the Section Molecular Nanoscience)

Chitosan Materials: Recent Advances in Modification, Properties and Application

edited by

Gabriela Dudek

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2312 | Submission Open

Keywords: chitosan materials; biomedical applications; agriculture and food industry; water treatment and environmental applications; nanotechnology and advanced materials

(This special issue belongs to the Section Macromolecules)

Mast Cell Disorders: From Molecular Mechanisms to Therapeutic Approaches

edited by Ehud Razin and

Sagi Tshori

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2253 | Submission Open

Keywords: mastocytosis; mast cell activation syndrome; mast cell disorders; theurapeutic approaches; molecular mechanisms; tumor neovascularization; inflammatory diseases; asthma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Study of Neurodevelopmental and Neurological Disorders

edited by

Kazuhito Toyooka

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1469 | Submission Open

Keywords: autism spectrum disorder; ADHD; schizophrenia; intellectual disability; Alzheimer’ s disease; Parkinson’ s disorder; traumatic brain injury; epilepsy; neurodevelopmental disorders; neurological diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Alzheimer’s Disease

edited by Sudip Dhakal

submission deadline 31 Aug 2025 | 4 articles | Viewed by 1443 | Submission Open

Keywords: Alzheimer’ s disease; amyloid beta; tauopathy; autophagy; stress response; mitochondrial dysfunction; cognitive decline; biomarkers; disease models

(This special issue belongs to the Section Molecular Neurobiology)

Identification of Novel Biomarkers Towards Improved Diagnosis and Management of Peripheral Vascular Diseases

edited by

Daniel P. Zalewski

submission deadline 31 Aug 2025 | Viewed by 1217 | Submission Open

Keywords: vascular pathophysiology; peripheral atherosclerosis; aneurysm; venous disorders; congenital vascular malformations; molecular biomarkers; diagnostic biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Aspects of Reproductive Medicine

edited by Wei Chen

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1125 | Submission Open

Keywords: spermatogenesis; oogenesis; microenvironment; organ interactions; molecular regulation; gametogenesis; signaling pathways; reproductive disorders

(This special issue belongs to the Section Molecular Biology)

Insights into Novel Food Packaging Materials: Properties, Molecular Mechanisms, and Advanced Applications

edited by

Di Wang

and

Qingjun Kong

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1009 | Submission Open

Keywords: food packaging; food materials; nano materials; degradable materials; edible materials; coating; shelf life; food preservation; postharvest control

(This special issue belongs to the Section Materials Science)

Molecular Research in Asthma and Allergy

edited by

Sylwia Smolińska

submission deadline 31 Aug 2025 | 1 articles | Viewed by 862 | Submission Open

Keywords: asthma; allergy; molecular mechanisms; exposome; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of MicroRNAs in Human Diseases: 2nd Edition

edited by

Lorenzo F. Sempere

submission deadline 31 Aug 2025 | 1 articles | Viewed by 833 | Submission Open

Keywords: microRNAs; miRNAs; miRs; preclinical models; target interaction; regulatory networks; oncology; cancer biology; cardiovascular disease; neurodegenerative conditions; diagnostic applications; therapeutic development and clinical trials

(This special issue belongs to the Section Molecular Genetics and Genomics)

Antioxidants: The Molecular Guardians Against Oxidative Stress

edited by

Karolina A. Wojtunik-Kulesza

submission deadline 31 Aug 2025 | 2 articles | Viewed by 814 | Submission Open

Keywords: antioxidant; free radical; oxidative stress; essential oils; secondary plant metabolites

(This special issue belongs to the Section Biochemistry)

Viruses as Therapeutic Tools: Medical and Biotechnological Applications

edited by

Víctor Romanowski

submission deadline 31 Aug 2025 | 2 articles | Viewed by 812 | Submission Open

Keywords: molecular virology; virus– host interactions; immunology; gene therapy vectors; vaccines; antivirals

(This special issue belongs to the Section Molecular Microbiology)

Bioactive Natural Compounds in Neuroscience and Neurodegenerative Disease Therapeutics

edited by

Sarmistha Mitra

submission deadline 31 Aug 2025 | Viewed by 786 | Submission Open

Keywords: natural products; bioactive metabolites; secondary metabolites; neuronal development; neurotrophins; neuromedicine; neurodegeneration; memory disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of Neutrophil Extracellular Traps (Nets) in Human Diseases

edited by Eisuke F. Sato

submission deadline 31 Aug 2025 | 1 articles | Viewed by 763 | Submission Open

Keywords: neutrophil extracellular traps (NETs); neutrophils; inflammation; autoimmune diseases; cardiovascular diseases; tumor metastasis; thrombosis; molecular mechanisms; disease progression; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Heart Failure: From Bench to Bedside

edited by

Nadia Aspromonte

submission deadline 31 Aug 2025 | 1 articles | Viewed by 612 | Submission Open

Keywords: heart failure; cardiac biomarkers; medical therapy; molecular pathways; prognosis; target therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Polymeric Biomaterials

edited by

Diego Acevedo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 603 | Submission Open

Keywords: biopolymers; biocomposites; nanomaterials; applications

(This special issue belongs to the Section Materials Science)

Therapeutic Horizons of Oligosaccharides: Molecular Mechanisms and Therapeutic Potential

edited by

Abdelali Daddaoua

and

María Núñez-Núñez

submission deadline 31 Aug 2025 | 1 articles | Viewed by 601 | Submission Open

Keywords: oligosaccharides; bacterial infection; multidrug-resistant

(This special issue belongs to the Section Molecular Microbiology)

Microbial Genomics in the Omics Era

edited by

Surajit De Mandal

submission deadline 31 Aug 2025 | 1 articles | Viewed by 575 | Submission Open

Keywords: microbe; bioinformatics; DNA; RNA; protein; sequencing; structure; omics

(This special issue belongs to the Section Molecular Microbiology)

Vitamin K in Disease Mechanisms and Therapy

edited by Maria Kokozidou

submission deadline 31 Aug 2025 | Viewed by 532 | Submission Open

Keywords: vitamins K; vitamins K-soluble proteins; vitamin K-dependent clotting factors; matrix Gla protein; calcification of blood vessels; vascular stiffness; cardiac output; stroke volume

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Structural and Functional Properties of G-Quadruplexes and Aptamers

edited by

Antonella Virgilio

Veronica Esposito

and

Aldo Galeone

submission deadline 31 Aug 2025 | 1 articles | Viewed by 495 | Submission Open

Keywords: G-quadruplex structure; aptamer; DNAzyme; catalytic G-quadruplexes

(This special issue belongs to the Section Molecular Biology)

Biological and Molecular Aspects of Exercise Adaptation

edited by

Alessandra Modesti

submission deadline 31 Aug 2025 | 1 articles | Viewed by 491 | Submission Open

Keywords: exercise; redox homeostasis; metabolic state; biological; physiological

(This special issue belongs to the Section Molecular Biology)

Physiological and Pathological Hypoxia: The Battle between the Protective and Deleterious Effects of Oxygen Deprivation

edited by

Michele Samaja

Michele Maffia

Rita Paroni

and Giacomo Strapazzon

submission deadline 31 Aug 2025 | Viewed by 489 | Submission Open

Keywords: physiological hypoxia; pathological hypoxia; hypoxia; signalling pathway; inflammation; oxygen transport

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Environmental Influences on Cellular Responses

edited by

Marcus Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 479 | Submission Open

Keywords: cell/environment interaction; cell signaling; mechanobiology; photobiology; thermobiology; enviromics; cell-cell communication; cell-cell interaction

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition

edited by

Hui Qiao

and Hongtuo Fu

submission deadline 31 Aug 2025 | 1 articles | Viewed by 476 | Submission Open

Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnosis and Treatment of Colorectal Cancer

edited by Steven T. Brower and Robert Pergolizzi

submission deadline 31 Aug 2025 | Viewed by 435 | Submission Open

Keywords: colorectal cancer; biomarkers; epigenetics; targeted therapy; chemoresistance; personalized cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Cutting Edge Advances in Antitumor Properties of Natural Products

edited by

Francesca Giordano

and

Maria Luisa Panno

submission deadline 31 Aug 2025 | Viewed by 412 | Submission Open

Keywords: natural product; cancer; cell signaling; cell death and differentiation; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Research on Cancer Stem Cells

edited by

Ilze Štrumfa

submission deadline 31 Aug 2025 | Viewed by 396 | Submission Open

Keywords: cancer stem cells; tumour microenvironment; pancreatic cancer; glioblastoma; gastric cancer; breast cancer; lung cancer; colorectal cancer; renal cancer; liver cancer; melanoma; leukemia; lymphoma

(This special issue belongs to the Section Molecular Oncology)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 363 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

Nanoparticles in Molecular Pharmaceutics

edited by

Qingxin Mu

submission deadline 31 Aug 2025 | Viewed by 270 | Submission Open

Keywords: nanoparticles; molecular pharmaceutics; drug delivery; nanomedicine; nanoformulation

(This special issue belongs to the Section Molecular Nanoscience)

Cutting-Edge Innovations in Molecular and Nanoscale Engineering for Energy Applications

edited by

Mohammad R. Thalji

and

Farzaneh Mahmoudi

submission deadline 31 Aug 2025 | Viewed by 211 | Submission Open

Keywords: nanostructured electrode materials; energy storage; energy conversion; energy materials

(This special issue belongs to the Section Materials Science)

Role of MicroRNAs in Health and Diseases

edited by

Roberto Madeddu

submission deadline 31 Aug 2025 | Viewed by 200 | Submission Open

Keywords: miRNA; cancer; biomarkers; function; miRNA target

(This special issue belongs to the Section Molecular Genetics and Genomics)

Genes and Human Diseases: 3rd Edition

edited by

Mikhail I. Churnosov

submission deadline 31 Aug 2025 | Viewed by 198 | Submission Open

Keywords: genes; human diseases; genetic-epidemiological studies; genetic factors; susceptibility

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Translation Process, Molecular Mechanism, and Recognition Methods of Post-Translational Modifications of Proteins

edited by

Hao Lin

submission deadline 31 Aug 2025 | Viewed by 193 | Submission Open

Keywords: DNA replication; repair; and transcription; post-translational modifications; chromatin; acetylation; methylation; phosphorylation; ubiquitination and ubiquitin-like modifiers; histone modifications

(This special issue belongs to the Section Molecular Biology)

Neurotoxicity: Cellular Death Mechanisms in the Pathogenesis of Neurodegenerative Diseases

edited by

Mohammed Jakaria

and

Jason Cannon

submission deadline 31 Aug 2025 | Viewed by 184 | Submission Open

Keywords: neurotoxicity; cellular stress; neuronal cell death; ferroptosis; neurodegeneration; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

PD-L1 – PD1 Signaling Axis: From Mechanism to Therapeutics

edited by

Grazyna Kochan

and

David Escors

submission deadline 31 Aug 2025 | Viewed by 183 | Submission Open

Keywords: PD-L1/PD1 immune checkpoints; cancer; mechnistic insights and resistances; adaptive immune regulation; therapeutic strategies

(This special issue belongs to the Section Molecular Oncology)

Diverse Biomolecular Probes in the Development of Single-Molecule Biosensors

edited by

Kevin D. Belfield

and

Xiaohan Chen

submission deadline 31 Aug 2025 | Viewed by 179 | Submission Open

Keywords: biomolecular probes; single-molecule method; biosensors; diseases diagnosis; biomarkers; nanotechnology

(This special issue belongs to the Section Materials Science)

Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches

edited by

Bin Yang

submission deadline 31 Aug 2025 | Viewed by 175 | Submission Open

Keywords: kidney injury; repair; immunoresponse; biomarker; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Glycoconjugates: From Structure to Therapeutic Application

edited by Rosana Ribić

submission deadline 31 Aug 2025 | 1 articles | Viewed by 175 | Submission Open

Keywords: glycoconjugates (glycoproteins and glycopeptides; glycolipids; proteoglycans); glyconanoparticles; carbohydrate-based therapeutics; glycomics; glycosylation; glycoengineering; glycobiology; synthesis of glycoconjugates; vaccine development; drug delivery; biomarkers; diagnostics; immunotherapy; regenerative medicine; therapeutic applications

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research on Immune Response to Virus Infection and Vaccines

edited by

Giulia Matusali

submission deadline 31 Aug 2025 | Viewed by 172 | Submission Open

Keywords: immunogenicity; emerging pathogen vaccination; molecular and cellular determinants of vaccine responses in immunocompromised individuals; predictive markers of immune response; laboratory methods to dissect immune responses to infections and vaccinations

(This special issue belongs to the Section Molecular Immunology)

Anticancer Agents of the Future: From Specific Molecular Targets to Individual Patient Profile

edited by

Zofia Mazerska

submission deadline 31 Aug 2025 | Viewed by 171 | Submission Open

Keywords: anticancer drug research; selective antitumor therapy; tumor cell molecular targets; tumor healthy cells selectivity; cancer cell metabolism; anticancer drug delivery; individual anticancer therapy; dual targeting anticancer therapy

(This special issue belongs to the Section Molecular Oncology)

Plant Genomics and Genome Editing, 3rd Edition

edited by

Hikmet Budak

submission deadline 31 Aug 2025 | Viewed by 166 | Submission Open

Keywords: next-generation sequencing; structural and functional genomics; SNPs; miRNA; LncRNA; CRISPR/Cas9; TALEN; genome editing

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Products from Plants: Association with Human Health and Therapeutic Benefits

edited by

Andrey Marchev

and

Nikolina Mihaylova

submission deadline 31 Aug 2025 | 1 articles | Viewed by 164 | Submission Open

Keywords: botanical products; phytochemicals; bio/pharmacological compounds; cellular and molecular targets; molecular and physiological mechanism; human health; disease prevention and treatment; inflammatory diseases; age-related disorders; chronic and (auto)immune diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Ferrocene-Based Molecular Research: Synthesis, Properties, and Applications

edited by

Mojca Čakić Semenčić

submission deadline 31 Aug 2025 | Viewed by 159 | Submission Open

Keywords: ferrocene; organometallic chemistry; bioorganometallic chemistry; ferrocene derivatives; synthesis; applications; bioconjugates

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 31 Aug 2025 | Viewed by 156 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Neurodegenerative Disorders: Advances in Mechanisms, Models, and Therapeutics

edited by Craig Bennett

submission deadline 31 Aug 2025 | Viewed by 154 | Submission Open

Keywords: TDP-43; C9orf72; dipeptide repeat; proteotoxicity; cryptic exon exclusion; L-BMAA

(This special issue belongs to the Section Molecular Neurobiology)

Multidrug Resistance in Cancer: Molecular Mechanisms and Therapeutic Challenges

edited by

Odília Queirós

and

Patrícia M. A. Silva

submission deadline 31 Aug 2025 | Viewed by 154 | Submission Open

Keywords: cancer therapy; MultiDrug Resistance (MDR); Pgp; efflux pumps; tumor microenvironment; anticancer drug target; combination therapy; novel anticancer agents

(This special issue belongs to the Section Molecular Biology)

Endocrinology of Pregnancy

edited by

Georgios Valsamakis

submission deadline 31 Aug 2025 | Viewed by 149 | Submission Open

Keywords: pregnancy; endocrine system; fetal development; maternal health; metabolism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Amyotrophic Lateral Sclerosis: From Molecular Basis to Therapies

edited by

Matteo Bordoni

submission deadline 31 Aug 2025 | 1 articles | Viewed by 147 | Submission Open

Keywords: ALS; pathomechanisms; genetics; epigenetics; disease models; neuroinflammation; mithocondria; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Enzymes in Biocatalysis

edited by

Simona Varriale

Samuel De Visser

and

Salvatore Fusco

submission deadline 31 Aug 2025 | Viewed by 146 | Submission Open

Keywords: biocatalysis; bioprocess; enzyme immobilization; enzyme production; response surface methodology (RSM); enzymatic-assisted extraction; enzymatic-catalyzed synthesis; enzyme modelling; bioreactor; bioconversion; cascade biocatalysis; enzymatic kinetic; enzyme engineering; ultrasound-assisted enzymatic reaction; directed evolution; machine learning-assisted enzyme engineering; waste-to-value bioprocesses

(This special issue belongs to the Section Biochemistry)

Molecular Regulation and Mechanisms of Nitric Oxide in Endothelial Cells

edited by

Roberto Berra-Romani

and

Francesco Moccia

submission deadline 31 Aug 2025 | Viewed by 146 | Submission Open

Keywords: nitric oxide (NO); endothelial cells; endothelial nitric oxide synthase (eNOS); vascular homeostasis; vasodilation; endothelial dysfunction; molecular signaling; vascular diseases; reactive oxygen species (ROS); nitric oxide regulation

(This special issue belongs to the Section Biochemistry)

Displaying special issue 1101-1150 on page 23 of 68.

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