Mast Cell Disorders: From Molecular Mechanisms to Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 1188
Special Issue Editors
Interests: mast cells; lysyl tRNA synthetase; Nudt2; di-adenosine tetraphosphate; signal transduction; Ap4A hydrolase; Hint1; mast cell activation
Special Issues, Collections and Topics in MDPI journals
2. Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel
Interests: mast cells; lysyl tRNA synthetase; Nudt2; di-adenosine tetraphosphate; cardiac hypertrophy; cardiac amyloidosis; transtherytin; cardiac imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mast cells are immune cells derived from the myeloid lineage. Mast cell progenitors emerge from the bone marrow, circulate, home to various tissues, and differentiate into mature mast cells. These cells express a high affinity Fc region of the IgE antibody (FcεRI) on their surface and can secrete a plethora of mediators and cytokines. Immediate-type hypersensitivity is the most known mast cell dysfunction.
This Special Issue offers an open access forum for original research articles and reviews that will focus on mast cell disorders other than immediate-type hypersensitivity. Relevant disorders would be primary disorders, i.e, mastocytosis and mast cell activation syndrome (MCAS), and secondary disorders, e.g., infections, inflammatory bowel disease, asthma, tumor neovascularization, and atherosclerosis. Suggested topics include mechanistic insights, diagnostic tools, large-scale epidemiologic data, and therapeutic approaches.
We look forward to receiving your contributions.
Many thanks,
Prof. Dr. Ehud Razin
Dr. Sagi Tshori
Guest Editors
Manuscript Submission Information
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Keywords
- mastocytosis
- mast cell activation syndrome
- mast cell disorders
- theurapeutic approaches
- molecular mechanisms
- tumor neovascularization
- inflammatory diseases
- asthma
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