Neurodegenerative Disorders: Advances in Mechanisms, Models, and Therapeutics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 1032
Special Issue Editor
Special Issue Information
Dear Colleagues,
We are pleased to announce a Special Issue of the International Journal of Molecular Sciences (IJMS) titled “Neurodegenerative Disorders: Advances in Mechanisms, Models, and Therapeutics.” This Special Issue will highlight cutting-edge research on the molecular and cellular mechanisms underlying neurodegenerative diseases, with a focus on aging, disease pathogenesis, therapeutic interventions, and preclinical models.
Neurodegenerative disorders—including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis—present significant challenges due to their complex pathology and limited treatment options. We welcome original research articles, as well as full- and mini-reviews addressing key aspects such as genetic and epigenetic contributions, protein aggregation, neuroinflammation, and synaptic alterations driving disease progression. Additionally, studies on innovative therapeutic strategies, drug discovery, and advanced disease models are highly encouraged.
We also invite insightful reviews exploring the limited success of recent treatment approaches and the challenges in translating research findings into clinical practice. We hope that this Special Issue will be of great interest to researchers in molecular neuroscience, pharmacology, and translational medicine.
We look forward to your contributions in advancing the field.
Dr. Craig Bennett
Guest Editor
Manuscript Submission Information
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Keywords
- TDP-43
- C9orf72
- dipeptide repeat
- proteotoxicity
- cryptic exon exclusion
- L-BMAA
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