The Translation Process, Molecular Mechanism, and Recognition Methods of Post-Translational Modifications of Proteins
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: closed (20 February 2026) | Viewed by 914
Special Issue Editor
Interests: protein informatics; peptide sequence analysis; machine learning applications in biological macromolecular data; biomarker; protein post-translational modification site; systems biology; clinical data analysis; disease risk prediction; analysis and identification of DNA regulatory elements
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue aims to explore the intricate relationship between protein synthesis and the subsequent modifications that influence protein function and cellular processes. Protein translation is a complex and highly regulated process that involves the decoding of genetic information into functional proteins. However, the functional diversity of proteins extends beyond their primary structure, with post-translational modifications (PTMs) playing a crucial role in regulating protein activity, stability, localization, and interactions. These modifications, including phosphorylation, acetylation, methylation, and ubiquitination, are key to cellular signaling, gene expression regulation, and the response to environmental stimuli. This issue will focus on recent advancements in understanding the molecular mechanisms underlying PTMs, how they influence protein function, and their contribution to cellular homeostasis and disease mechanisms. By bridging the translation process with PTM pathways, this Special Issue aims to provide insights into the dynamic regulation of proteins, opening new avenues for therapeutic interventions targeting protein modifications in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases.
Prof. Dr. Hao Lin
Guest Editor
Manuscript Submission Information
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Keywords
- DNA replication, repair, and transcription
- post-translational modifications
- chromatin
- acetylation, methylation, phosphorylation
- ubiquitination and ubiquitin-like modifiers
- histone modifications
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