Anticancer Agents of the Future: From Specific Molecular Targets to Individual Patient Profile
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 160
Special Issue Editor
Interests: metabolic transformations of antitumor agents; general approach and the selected pathways; enzyme families involved in metabolism of anticancer therapeutics: P450s, FMOs, UGTs, SULTs, AOXs, XORs, MAOs, ALDHs, (liver and cytosolic enzymes); the relevance of metabolic transformations to drug resistance and to the activation mechanism in cancer treatments
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Special Issue Information
Dear Colleagues,
The current challenge of anticancer drug research is the development of specific and effective therapy able to reduce cancer cell survival with minimal harm to surrounding healthy cells. Firstly, a novel approach to anticancer therapy is developed with the goal of new selective molecular targets. Innovative strategies take into account many target molecules, which participate in the specific metabolic pathways necessary for the survival of cancer cells, including the elements of the cancer cell microenvironment. The second crucial element of advanced research on anticancer drugs is new attractive methods of drug formulation, and particularly of drug delivery. They are developed primarily by employing a wide set of nanoparticles. This approach is also expected to improve tailored therapy for individual patients. Moreover, drug delivery approaches relate to dual-targeting therapy as oncolytic virotherapy or gene therapy combined with agents known to amplify anticancer effects. Thus, in the present Special Issue, “Anticancer Agents of the Future: From Specific Molecular Targets to Individual Patient Profile”, we propose to present the results of your research, which will consider the above and other new approaches, leading to the improvement of the therapeutic efficacy of studied anticancer agents. Research with respect to new specific and effective molecular targets for potent and applied antitumor drugs will be preferred.
Prof. Dr. Zofia Mazerska
Guest Editor
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Keywords
- anticancer drug research
- selective antitumor therapy
- tumor cell molecular targets
- tumor healthy cells selectivity
- cancer cell metabolism
- anticancer drug delivery
- individual anticancer therapy
- dual targeting anticancer therapy
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