Neurotoxicity: Cellular Death Mechanisms in the Pathogenesis of Neurodegenerative Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 146
Special Issue Editors
Interests: cellular stress; cell death; neurotoxicity; neurodegeneration; neurotherapeutics
Interests: neurobiology of disease; neurodegeneration; neurotoxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurotoxicity resulting in adverse effects on the nervous system and neurological function is a serious public health concern. This complex area of research presents significant challenges for scientists in both neuroscience and toxicology. Growing evidence suggests a strong link between neurotoxicity and the development of neurodegenerative diseases, which generally lack effective treatments. Thus, understanding the intricate mechanisms behind neurotoxicity is essential for identifying and addressing the pathways involved in neurodegeneration.
This Special Issue aims at underscoring neurotoxicity as a critical factor in the progression of neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases. We invite submissions that provide innovative insights into the molecular mechanisms connecting toxic exposure to the onset and advancement of these conditions. Special attention will be given to potential therapeutic targets related to neurotoxicity, including ferroptosis—a regulated form of cell death caused by uncontrolled phospholipid peroxidation—and mitochondrial dysfunction, which are vital for mediating neurodegeneration. Furthermore, we encourage manuscripts that explore neuroprotective strategies designed to mitigate the harmful effects of neurotoxicity, thereby enhancing resilience against neurodegeneration.
Dr. Mohammed Jakaria
Prof. Dr. Jason Cannon
Guest Editors
Manuscript Submission Information
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Keywords
- neurotoxicity
- cellular stress
- neuronal cell death
- ferroptosis
- neurodegeneration
- neuroprotection
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