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Natural Products from Plants: Association with Human Health and Therapeutic Benefits

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 71

Special Issue Editors


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Guest Editor
Laboratory of Eukaryotic Cell Biology, Department of Biotechnology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria
Interests: natural products; plant-derived extracts and molecules; medicinal plants; plant in vitro systems; natural product pharmacology
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Special Issue Information

Dear Colleagues,

Plants and their products are mainly consumed for nutritional support, while a majority of the world population also relies on botanicals for health purposes, either as “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many plant-derived compounds have been known since ancient times to possess bio/pharmacological activities. Today, we are witnessing a global resurgence in interest and use of plant-based therapies to promote human health by preventing the onset and progression of diseases. Numerous randomized controlled trials have demonstrated the safety and efficacy of botanical products, establishing their importance as a viable source of lead compounds in drug discovery programs. Biomolecular studies have revealed hundreds of cellular and molecular targets for phytochemicals, including key transcription factors, receptors, enzymes, hormones, neurotransmitters, cytokines, lipids, and non-coding RNAs.

Extensive research on the preventative and therapeutic effects of natural products requires regular updating of the literature as to the developing potential roles of these compounds in different human diseases. This Special Issue (SI) attempts to provide an overview of the current pharmacological features and therapeutic benefits of phytopharmaceuticals in health and diseases by covering a wide scope, from chronic and (auto)immune to age-related disorders. Thus, this SI would provide profound insights on the regulatory effects of phytochemicals on molecular signatures associated with pathologies, disease biomarkers, and aging-related pathways.

The SI is open to original research articles, short communications, and reviews.

Dr. Andrey Marchev
Dr. Nikolina Mihaylova
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • botanical products
  • phytochemicals
  • bio/pharmacological compounds
  • cellular and molecular targets
  • molecular and physiological mechanism
  • human health
  • disease prevention and treatment
  • inflammatory diseases
  • age-related disorders
  • chronic and (auto)immune diseases

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