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Role of MicroRNAs in Health and Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 137

Special Issue Editor


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Guest Editor
Department of Biomedical Sciences, University of Sassari, Sassari, Italy
Interests: trace elements; cadmium; toxicity; neurodegenerative disorders; cancer stem cells; oncology; miRNA
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

MicroRNAs (miRNAs) are endogenous, short, noncoding RNA sequences of 18–25 nucleotides that regulate the expression of genes at the post-transcriptional level in a sequence-specific manner. Due to their high stability and the ability to detect them in human body fluids, miRNAs are being studied as a new class of biomarkers. Numerous studies have demonstrated their utility in biomedical research, particularly in cancer.

This Special Issue will focus on recent studies on microRNAs and their application in cancer research. The effect of miRNAs depends on their specific targets, and they can therefore exert tumor-promoting (oncomiRs) or tumor-suppressing functions. The early diagnosis of cancer is crucial to improving therapeutic outcomes and patient survival.  miRNAs could serve as excellent diagnostic candidates due to their remarkable stability in body fluids and their significant biological roles. In addition, their involvement in circulation, shielded from endogenous RNase activity, makes them particularly suitable for use as biomarkers in non-invasive diagnostic applications.

We welcome researchers to submit original research papers, reviews, and short communications.

Dr. Roberto Madeddu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • miRNA
  • cancer
  • biomarkers
  • function
  • miRNA target

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Published Papers

This special issue is now open for submission.
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