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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Focus on Antioxidants and Human Diseases

edited by

Marija S. Plješa-Ercegovac

submission deadline 20 May 2025 | 4 articles | Viewed by 11541 | Submission Open

Keywords: antioxidants; epidemic; COVID-19; oxidative stress; antioxidant capacity; vitamins; human diseases

(This special issue belongs to the Section Biochemistry)

News in Skin Diseases: From Basic Mechanisms to Therapies

edited by

Takemichi Fukasawa

submission deadline 20 May 2025 | 4 articles | Viewed by 11449 | Submission Open

Keywords: skin diseases; psoriasis; atopic dermatitis; scleroderma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Cytokines in Diseases

edited by

Svetlana Khaiboullina

submission deadline 20 May 2025 | 6 articles | Viewed by 11258 | Submission Open

Keywords: cytokines; inflammation; immune response; genetics; epigenetics; disease; infection; pathogen-associated molecular patterns; damage-associated molecular patterns; pattern-recognizing receptors; treatment

(This special issue belongs to the Section Biochemistry)

Molecular Research on Skeletal Muscle Biology

edited by

Atsushi Asakura

submission deadline 20 May 2025 | 6 articles | Viewed by 11244 | Submission Open

Keywords: skeletal muscle; muscular dystrophy; satellite cell; muscle regeneration; myofibrosis; exercise

(This special issue belongs to the Section Molecular Biology)

Influenza Viruses: Infection and Genomics

edited by

Daniele Focosi

submission deadline 20 May 2025 | 5 articles | Viewed by 11202 | Submission Open

Keywords: influenza viruses; avian influenza; virus replication; infection; convergent evolution; restriction factors

(This special issue belongs to the Section Molecular Immunology)

New Drugs Regulating Cytoskeletons in Human Health and Diseases

edited by

Gilles Breuzard

Maxime Robin

and

Hervé Kovacic

submission deadline 20 May 2025 | 5 articles | Viewed by 11157 | Submission Open

Keywords: tubulin; actine; cytoskeletons; associated proteins; pharmacological agent; repurposing of drugs; oncology; neurodegenerative diseases

(This special issue belongs to the Section Molecular Pharmacology)

Latest Research on Mesenchymal Stem Cells

edited by Marcel Costuleanu

submission deadline 20 May 2025 | 7 articles | Viewed by 11122 | Submission Open

Keywords: mesenchymal stem cell; MSC; niche; tissue homeostasis; exosomes; microvesicles; cancer; mitochondrial exchange; MSC secretome

(This special issue belongs to the Section Molecular Biology)

New Horizon for Non-coding RNAs

edited by

Hiroki Sato

submission deadline 20 May 2025 | 6 articles | Viewed by 10897 | Submission Open

Keywords: microRNAs; long noncoding RNAs; circular RNAs; transcriptional control; regulatory networks; function prediction

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into Atherosclerosis and Vascular Endothelial Cells

edited by

Yasuyuki Fujiwara

submission deadline 20 May 2025 | 5 articles | Viewed by 10485 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Development, Characterization and Applications of Novel Polymeric Materials and Composites

edited by

Daniel Dumitru Banciu

and

Xiao Hu

submission deadline 20 May 2025 | 7 articles | Viewed by 10447 | Submission Open

Keywords: diagnosis; therapy; polymers; composite materials; theoretical model

(This special issue belongs to the Section Macromolecules)

Advances in Natural Active Products Derived from Foods: Antioxidant, Antinociceptive and Anti-inflammatory Activities

edited by Ettore Novellino

submission deadline 20 May 2025 | 5 articles | Viewed by 10380 | Submission Open

Keywords: antioxidants; bioactive compounds; food-derived products; health benefits; nutraceuticals; inflammation; pain management

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research in Viral Hepatitis and Liver Cancer

edited by

Teh-Ia Huo

submission deadline 20 May 2025 | 4 articles | Viewed by 10168 | Submission Open

Keywords: hepatitis B; hepatitis C; hepatitis D; hepatocellular carcinoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments

edited by

Chi Chiu Mok

submission deadline 20 May 2025 | 6 articles | Viewed by 10009 | Submission Open

Keywords: lupus erythematosus; lupus nephritis; SLE; LN; organ damage; pathogenesis; biomarkers; genomic; transcriptomic; metabolomic; treatments; therapeutic

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Occurrence, Evolution and Treatment of Glioblastoma: Second Edition

edited by

Antonella Mangraviti

submission deadline 20 May 2025 | 6 articles | Viewed by 9969 | Submission Open

Keywords: GBM; low-grade and high-grade; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; radiomics in brain tumors; re-surgery and re-radiation in GBMs; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

New Insights of Fungal and Plant Lipids: Structural Diversity, Metabolism and Applications

edited by

Ekaterina Kotlova

submission deadline 20 May 2025 | 5 articles | Viewed by 9958 | Submission Open

Keywords: lipidomics; fatty acids; glycerolipids; sphingolipids; sterols; oxylipins; fungal and plant lipid metabolism

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Targeted Therapies and Precision Medicine for Malignant Diseases

edited by

Anica Dricu

submission deadline 20 May 2025 | 6 articles | Viewed by 9858 | Submission Open

Keywords: personalized medicine; molecular targeted therapy; malignant diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Regenerative Medicine: Biomaterials and Stem Cell Research

edited by Silvia María Díaz-Prado

submission deadline 20 May 2025 | 4 articles | Viewed by 9787 | Submission Open

Keywords: regenerative medicine; stem cell; biomaterial; bioprinting; tissue engineering; tissue and organ transplant; organ scarcity

(This special issue belongs to the Section Materials Science)

Advances in Graphene Film and Composites

edited by

Karolina Anna Drogowska-Horná

submission deadline 20 May 2025 | 3 articles | Viewed by 9552 | Submission Open

Keywords: graphene composites; van der Waals heterostructures; graphene– oxide thin-films composites; graphene functionalization

(This special issue belongs to the Section Materials Science)

Functional Nanomaterials: Structures, Compositions and Various Applications

edited by

Magdalena Laskowska

submission deadline 20 May 2025 | 6 articles | Viewed by 9345 | Submission Open

Keywords: functional materials; nanomaterials; nanostructures; nanoelectronics; molecular electronics; nanosensors; nanodevices; 2D materials; molecular magnetism

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Advances on Insulin Resistance and Metabolic Dysfunction, 2nd Edition

edited by

Melania Manco

and

Amalia Gastaldelli

submission deadline 20 May 2025 | 3 articles | Viewed by 9318 | Submission Open

Keywords: dysregulated fatty acid and/or branched chain amino acids metabolism; metabolic inflexibility; tissue lipid accumulation; lipotoxicity and lipid mediated cell signaling; insulin resistance reversal; cancer development; low-grade inflammation and/or altered expression; synthesis and degradation and bioavailability of IGF binding proteins; environmental chemicals; mechanisms of T3D; microbiota and antimicrobials modulation; endocrine disruptors; altered immune system homeostasis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Insight into Gestational Diabetes Mellitus

edited by Marcin Trojnar and

Zaneta Kimber-Trojnar

submission deadline 20 May 2025 | 5 articles | Viewed by 9234 | Submission Open

Keywords: gestational diabetes mellitus; biomarkers; maternal risk factors; fetal programming; maternal programming; insulin resistance; endothelial dysfunction; inflammation; oxidative stress; placental growth factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Gynecologic Cancer

edited by

Alicja Forma

submission deadline 20 May 2025 | 6 articles | Viewed by 9107 | Submission Open

Keywords: ovarian cancer; uterine cancer; cervical cancer; vaginal cancer; vulvar cancer

(This special issue belongs to the Section Molecular Oncology)

Role of p53 Family in Targeted Therapy of Cancers

edited by

Ignacija Vlasic

and

Neda Slade

submission deadline 20 May 2025 | 3 articles | Viewed by 9070 | Submission Open

Keywords: p53 family of proteins; p53 family isoforms/splice variants; p53 family crosstalk; mutant p53; altered expression of p53 family members/isoforms; cancer progression; targeted therapy; therapy resistance

(This special issue belongs to the Section Molecular Oncology)

Autophagy, Cellular Senescence and Oxidative Stress in Ageing and Age-Related Diseases

edited by

Varvara Trachana

submission deadline 20 May 2025 | 4 articles | Viewed by 8753 | Submission Open

Keywords: autophagy; oxidative stress; antioxidants; homeostasis; senescence; ageing; age-related diseases; reactive oxygen species; macromolecular damage; cytotoxic stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

In Honor of Elie Metchnikoff, a Nobel Prize Winner, Who Discovered Macrophages as Phagocyte Cells Involved in the Process of Innate Immunity

edited by

Pierre Tennstedt

submission deadline 20 May 2025 | 4 articles | Viewed by 8742 | Submission Open

Keywords: macrophages; monocytes; phagocytes; fibroblast; cytokines; chronic disease; autoimmune disease; inflammatory disease; immune response; disease treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Computational Approaches in Drug Design: Novel Methodologies and Applications

edited by

Serena Vittorio

submission deadline 20 May 2025 | 4 articles | Viewed by 8648 | Submission Open

Keywords: drug design; computational approaches; molecular docking; molecular dynamics; pharmacophore modeling; homology modeling; computer aided drug design; ADME/Tox predictions; artificial intelligence

(This special issue belongs to the Section Molecular Informatics)

Molecular Advances in the Diagnosis and Drug Therapies of Atherosclerotic Cardiovascular Diseases (ASCVD)

edited by

Nikolaos Kadoglou

submission deadline 20 May 2025 | 2 articles | Viewed by 8581 | Submission Open

Keywords: atherosclerotic cardiovascular diseases; gene expression; gene therapy; biomarkers; lipid lowering; hypercholesterolemia; PCSK9; immunomodulators; anti-inflammatory drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Atherosclerosis: From Molecular Biology to Therapeutic Perspective: 6th Edition

edited by

Ida Daniela Perrotta

submission deadline 20 May 2025 | 4 articles | Viewed by 8208 | Submission Open

Keywords: atherosclerosis; vascular smooth muscle cell; inflammation; endothelium; cell senescence; apoptosis; lipid metabolism; oxidative stress; nitric oxide; exosomes; vascular calcification; cytokines; growth factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Heart Disease: Genomics, Proteomics, and Bioinformatics of Heart Research

edited by Justyna Fert-Bober

submission deadline 20 May 2025 | 5 articles | Viewed by 8197 | Submission Open

Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Polymeric Materials for Biomedical Applications, Drug and Gene Delivery

edited by

Ilya E. Nifant'ev

submission deadline 20 May 2025 | 6 articles | Viewed by 8165 | Submission Open

Keywords: biodegradable polymers; polyesters; scaffolds; tissue engineering; drug delivery; gene delivery; functional materials; biomedical application

(This special issue belongs to the Section Macromolecules)

Molecular Aspects of Autoimmune Diseases

edited by Raquel López Mejías

submission deadline 20 May 2025 | 4 articles | Viewed by 8158 | Submission Open

Keywords: genetics; epigenetics; molecules; cellules; autoimmune diseases; inflammation

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms and Therapies of Pancreatic Cancer: 2nd Edition

edited by

Donatella Delle Cave

submission deadline 20 May 2025 | 5 articles | Viewed by 8136 | Submission Open

Keywords: pancreatic cancer; metabolism; cellular plasticity; tumor microenvironment; target therapy

(This special issue belongs to the Section Molecular Oncology)

Advances In and Insights into the Treatment of Glaucoma

edited by Da-Wen Lu

submission deadline 20 May 2025 | 5 articles | Viewed by 8073 | Submission Open

Keywords: glaucoma; glaucoma treatment; molecular mechanism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Plant Molecular Responses to Abiotic Stresses

edited by

Dong-Gwan Kim

submission deadline 20 May 2025 | 10 articles | Viewed by 7999 | Submission Open

Keywords: abiotic stress responses (heat; drought; salinity; nutrient deficiency; oxygen quality; flooding; light; etc.); genetically modified plants; CRISPR/Cas-mediated stress overcome; microplastic/nanoparticle stresses; bioinformatic studies; miRNAs and other noncoding RNAs involved in abiotic stresses in plants; secondary metabolite synthesis

(This special issue belongs to the Section Molecular Plant Sciences)

Emerging Biotechnological Approaches for Natural Antiviral Molecules Discovery

edited by

Rosamaria Pennisi

Maria Teresa Sciortino

and

Giuseppina Mandalari

submission deadline 20 May 2025 | 3 articles | Viewed by 7911 | Submission Open

Keywords: natural antivirals; biotechnology; viruses; cellular signalling; natural bioactive compounds; viral infections; antiviral therapeutics; virus inhibition assays

(This special issue belongs to the Section Molecular Microbiology)

Extracellular Vesicles in Microbes, Pathogens and Infectious Diseases: 2nd Edition

edited by

Franklin W.N. Chow

and

Russell M. Morphew

submission deadline 20 May 2025 | 3 articles | Viewed by 7836 | Submission Open

Keywords: extracellular vesicles; infectious diseases; host– pathogen interaction; pathogens; viruses; fungi; parasites; helminths; bacteria; animals; plants; virulence; genomics; transcriptomics; small RNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Underpinnings of Schizophrenia Spectrum Disorders

edited by

Paola Rocca

and

Claudio Brasso

submission deadline 20 May 2025 | 6 articles | Viewed by 7786 | Submission Open

Keywords: schizophrenia spectrum disorders; central nervous system (CNS); psychotic disorders

(This special issue belongs to the Section Molecular Neurobiology)

Drug Delivery to the Central Nervous System: From Design, Synthesis, and Evaluation

edited by

Masaru Tanaka

submission deadline 20 May 2025 | 2 articles | Viewed by 7731 | Submission Open

Keywords: central nervous system; central nervous system diseases; drug delivery systems; blood– brain barrier; blood– cerebrospinal fluid barrier; drug design; nanomedicine; neuropharmacology; neuroprotective agents; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Biology of Hypoxia

edited by Yuji Arai

submission deadline 20 May 2025 | 6 articles | Viewed by 7688 | Submission Open

Keywords: hypoxia; HIFs; normoxic environment

(This special issue belongs to the Section Molecular Biology)

Progress in Research on Endocrine-Disrupting Chemicals

edited by Efthymia Kitraki

submission deadline 20 May 2025 | 5 articles | Viewed by 7579 | Submission Open

Keywords: Endocrine-Disrupting Chemicals (EDCs); chemical mixtures; biomonitoring; cohort studies; in vivo and in vitro models; mechanisms of action; risk assessment

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Exploring Rare Diseases: Genetic, Genomic and Metabolomic Advances

edited by

Judit Bene

and

Kinga Hadzsiev

submission deadline 20 May 2025 | 8 articles | Viewed by 7547 | Submission Open

Keywords: rare diseases; genotype– phenotype analyses; NGS; mass spectrometry; biomarker discovery; molecular targeted therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Biology and the Genetic Breeding of Aquatic Animals: Breakthroughs and Challenges

edited by

Hongyan Xu

submission deadline 20 May 2025 | 6 articles | Viewed by 7469 | Submission Open

Keywords: transgenic; genetic breeding; omics; gene expression and regulation; aquatic animals

(This special issue belongs to the Section Molecular Biology)

Current Molecular Progress on Cell and Gene Therapies

edited by

Elena Herrera Carrillo

submission deadline 20 May 2025 | 4 articles | Viewed by 7347 | Submission Open

Keywords: gene therapy; cell therapy; gene delivery; gene editing; stem cells; regenerative medicine; CRISPR-Cas; viral vectors; non-viral vectors; immunotherapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug Treatment for Bacterial Infections

edited by Janusz Madaj

submission deadline 20 May 2025 | 6 articles | Viewed by 7252 | Submission Open

Keywords: bacterial infection; antibiotic-resistant bacteria; new agents in the treatment of bacterial infections; optimization of the use of already registered drugs; single antibacterial agents; combined antibacterial agents; new drug forms

(This special issue belongs to the Section Molecular Pharmacology)

Innovations in Molecular Treatment of Hematological Malignancies

edited by

Francesco Pallotti

submission deadline 20 May 2025 | 3 articles | Viewed by 7226 | Submission Open

Keywords: hematologic malignancies; target drugs; new immunotherapies; hematopoietic stem cell transplantation; CAR-Ts

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Uses and Applications of Cyclodextrins

edited by

Zoltan Juvancz

and

Cecilia Cagliero

submission deadline 20 May 2025 | 4 articles | Viewed by 7190 | Submission Open

Keywords: cyclodextrins; chiral separations; GC; HPLC; SFC; and CE; chiral recognition mechanisms; structure– chiral selectivity relationships; a combination of chromatographic and structure determination methods (e.g.; MS; NMR; CD; etc.)

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advanced Research on Chemokines and Chemokine Receptors

edited by

Bouchra Edderkaoui

submission deadline 20 May 2025 | 4 articles | Viewed by 7179 | Submission Open

Keywords: chemokines; chemokine receptors; chronic diseases; angiogenesis; fracture; regeneration; chemokine function; expression

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Insights into Ocular Changes Associated with Systemic Disorders and Conditions

edited by

Snježana Kaštelan

and

Katarzyna Zorena

submission deadline 20 May 2025 | 4 articles | Viewed by 7072 | Submission Open

Keywords: ocular pathology; systemic disorders; biomarkers; pathogenetic mechanism; cellular and molecular mechanisms; diagnostic techniques; imaging technologies; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Enzymes in Metabolic Processes

edited by

Koichi Fujisawa

submission deadline 20 May 2025 | 4 articles | Viewed by 6625 | Submission Open

Keywords: enzyme; metabolism; glycolysis; mitochondria; kinase; cell growth; carcinogenesis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Basis and Progress of Immunotherapy for Melanoma

edited by

George Ansstas

submission deadline 20 May 2025 | 3 articles | Viewed by 6578 | Submission Open

Keywords: melanoma; immune checkpoint inhibitors; immune therapies; T cell; NK cells

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 51-100 on page 2 of 66.

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