Molecular Dialogues in the Tumor Microenvironment: Mechanisms, Methods and Therapeutic Implications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 January 2026 | Viewed by 4
Special Issue Editor
Interests: tumor angiogenesis; vessel co-option; lung metastases; tissue fibrosis; pericytes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) plays a critical role in cancer progression, therapeutic resistance, and immune evasion. This Special Issue of International Journal of Molecular Sciences aims to advance our understanding of the intricate molecular interactions between tumor cells, immune cells, blood vessels, and the extracellular matrix. We particularly welcome contributions that explore novel methodological approaches—ranging from digital pathology to multi-omics strategies and advanced histopathological techniques—which help to dissect the cellular and molecular complexity of the TME. We invite original research articles and comprehensive review papers that shed light on various mechanisms, such as intercellular communication, matrix remodeling, tumor angiogenesis, immunomodulation, and the molecular landscape that shapes tumor behavior. Submissions that integrate innovative technologies with translational insights are especially welcome.
Dr. José M. Muñoz-Félix
Guest Editor
Manuscript Submission Information
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Keywords
- tumor microenvironment
- blood vessels
- immune cells
- spatial transcriptomics
- histology
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