New Insights into Antimicrobial Peptides with Anticancer Activity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 8
Special Issue Editor
Interests: protein biochemistry; proteomics; metabolomics; bioinformatics; antimicrobial peptide; plasma protein corona; nanoparticle; food biochemistry
Special Issue Information
Dear Colleagues,
As potential next-generation drugs, antimicrobial peptides (AMPs) are becoming increasingly popular since they are natural peptides, produced by all organisms, and active against multiple classes of pathogens. Due to their broad spectrum of biological activities, increased efforts are beign made to bring AMPs into clinical use. AMPs are also currently being investigated as anticancer peptides (ACPs) due to several factors: (a) their direct cytotoxicity against cancer cells; (b) their activity as immunomodulators targeting cancer cells; (c) their potential for use in anticancer drug delivery systems, which could potentially reduce the side effects of current chemotherapy; and (d) their synergistic effects with conventional chemotherapy, which would increase its effectiveness and overcome cancer resistance.
The field of AMPs with anticancer activity is rapidly evolving, with ongoing research on novel peptides and their potential applications in cancer treatment. Developing ACPs as highly effective/selective anticancer drugs is the first crucial step in the bench-to-bedside process.
I am pleased to launch this Special Issue, “New Insights into Antimicrobial Peptides with Anticancer Activity”, which covers all aspects of the selective actions of AMPs against cancer cells and their potential applications as ACPs. In this Special Issue, attention will be paid to the identification of AMPs with anticancer activity and on the new trends in the application of innovative approaches, such as omics, and coupled technologies for the assessment of the biological response of cancer cells to ACPs and the cellular and molecular characterization of AMP action in cancer.
Interested scholars are encouraged to submit up-to-date review and research articles concerning these topics.
Dr. Esther Imperlini
Guest Editor
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Keywords
- antimicrobial peptides
- cytotoxicity
- selective anticancer drugs
- omics approaches
- anticancer peptide action
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