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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ion Channels as Therapeutic Target: Drug Design and Pharmacological Investigation (3rd Edition)

edited by

Gabriella Guerrini

submission deadline 20 Aug 2026 | 7 articles | Viewed by 7333 | Submission Open

Keywords: LGIC; voltage-gated ion channel; other ion channels; biological studies; molecular modeling; drug design; synthesis

(This special issue belongs to the Section Molecular Pharmacology)

Functional Genomics in Translational Medicine

edited by

Cornelia Braicu

, Oana Zanoaga and

Ștefan Strilciuc

submission deadline 20 Aug 2026 | 2 articles | Viewed by 6839 | Submission Open

Keywords: functional genomics; omics approaches; drug response/resistance; therapeutic targets; genomics and transcriptomic alteration; bioinformatic analysis; data integration; human disease; personalized medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Innovative Strategies in the Design and Development of Anticancer Agents

edited by Sanjay Kumar

submission deadline 20 Aug 2026 | 4 articles | Viewed by 6834 | Submission Open

Keywords: chemotherapy; biomimetic; natural product analogs; prodrugs; nanodrugs; drug release

(This special issue belongs to the Section Molecular Pharmacology)

Fungal Genetics and Functional Genomics Research

edited by

Yuqi Qin

and

Jian Zhao

submission deadline 20 Aug 2026 | 7 articles | Viewed by 6679 | Submission Open

Keywords: enzymes; fungal genetics; fungi; gene editing; regulation; secondary metabolites; synthetic biology; transcription

(This special issue belongs to the Section Molecular Genetics and Genomics)

Neurodegenerative Diseases: Genetic Bases and Pathogenetic Mechanisms

edited by Emanuele Panza

submission deadline 20 Aug 2026 | 3 articles | Viewed by 6551 | Submission Open

Keywords: neurodegenerative diseases; molecular and cellular pathways; pathogenetic mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Neuropharmacological Innovations in Treating Neurodegenerative Diseases

edited by

Gabriela Cioca

submission deadline 20 Aug 2026 | 1 articles | Viewed by 6533 | Submission Open

Keywords: neuropharmacology; neurodegenerative disorders; targeted drug delivery; blood–brain barrier permeability; synaptic modulation; neuroprotective agents; disease-modifying therapies; molecular mechanisms of neurodegeneration; innovative drug targets; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Fish Nutrition, Biochemical Pathways, and Physiological Adaptations

edited by Paula Simó-Mirabet and Fernando Naya-Català

submission deadline 20 Aug 2026 | 2 articles | Viewed by 6473 | Submission Open

Keywords: fish; nutrition; metabolism; physiology; growth performance; fish stress; transcriptomics; metataxonomics; metagenomics; epigenomics; aquaculture

(This special issue belongs to the Section Molecular Biology)

Progress in Adipokines Research in Cardiovascular Health and Diseases

edited by

Morris Karmazyn

submission deadline 20 Aug 2026 | 4 articles | Viewed by 5786 | Submission Open

Keywords: adipokine receptors and cell signalling; adipokines and heart failure and hypertrophy; adipokines and myocardial ischemia; adipokines and hypertension; adipokines and thrombosis/atherosclerosis; adipokines and vascular/endothelial function, structure, and integrity; adipokines and cardiovascular inflammation; adipokines, adiposity, and cardiovascular disease in obesity

(This special issue belongs to the Section Molecular Biology)

Hearing Loss: Molecular Biological Insights, 2nd Edition

edited by María Beatriz Durán-Alonso

submission deadline 20 Aug 2026 | 4 articles | Viewed by 5349 | Submission Open

Keywords: genetics; microRNA; epigenetics; CRISPR; multi-omics; presbycusis; ototoxicity; development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Intestinal Diseases and Gut Microbiota

edited by

Anna Duda-Madej

submission deadline 20 Aug 2026 | 2 articles | Viewed by 5268 | Submission Open

Keywords: gut microbiota; dysbiosis; natural compounds; colorectal cancer; neurological diseases; autoimmune diseases; probiotics; gut-brain axis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Products in Cancer Prevention and Treatment—Second Edition

edited by

Simona Serini

and

Gabriella Calviello

submission deadline 20 Aug 2026 | 3 articles | Viewed by 5203 | Submission Open

Keywords: natural products; cancer; therapeutic strategies; novel molecular pathways

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Application of an Electron Microscope in the Study of Cell Structure

edited by

Ivana Bocina

submission deadline 20 Aug 2026 | 5 articles | Viewed by 5029 | Submission Open

Keywords: intracellular structure; organelles; cell surface structure; immuno-labeling

(This special issue belongs to the Section Molecular Biophysics)

Microbial Fermentation: Advances in Synthetic Biology, Metabolic Engineering, and Biomanufacturing

edited by

Yaokang Wu

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4768 | Submission Open

Keywords: microbial fermentation; synthetic biology; metabolic engineering; biomanufacturing; industrial biotechnology

(This special issue belongs to the Section Molecular Microbiology)

From Electronic Structure to Application: Computational Insights into Bioactive and Functional Molecules

edited by

Karolina Kula

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4384 | Submission Open

Keywords: molecular design; molecular modeling; substituent effect; reactivity descriptors; biological potential; in silico study; physicochemical properties; ADME; PASS; QSAR

(This special issue belongs to the Section Molecular Informatics)

Gene Regulation and Neurotoxicity in Alcohol Related Pathologies

edited by

Stefano Casalotti

submission deadline 20 Aug 2026 | 1 articles | Viewed by 4324 | Submission Open

Keywords: alcohol; ethanol; gene expression; neurotoxicity; epigenetics; polymorphisms; neu-rons; glial cell; plasticity

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Therapeutic Strategies for Pregnancy Complications

edited by

Joško Osredkar

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4211 | Submission Open

Keywords: pregnancy complications; placenta diseases; molecular mechanisms; therapeutics; biomarkers; preeclampsia; gestational diabetes; intrauterine growth restriction; maternal-fetal exchange; inflammation mediators

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Focus on Plant Biotechnology and Molecular Breeding

edited by

Magdalena Wróbel-Kwiatkowska

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4049 | Submission Open

Keywords: genetic engineering; plant transformation; applied biotechnology; functional genomics; crop plants; crop improvement; plant tissue cultures; secondary metabolites

(This special issue belongs to the Section Molecular Plant Sciences)

Cell Proliferation and Differentiation in Cancer

edited by

Sérgio Paulo Bydlowski

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4037 | Submission Open

Keywords: cell signaling; cell transduction; transcriptional and post-transcriptional pathways; growth factors; second messengers; cell proliferation; cell differentiation; cell metabolism; cell death; cell invasion

(This special issue belongs to the Section Molecular Oncology)

Advanced Research on Immune Cells and Cytokines (3rd Edition)

edited by

Athanasia Mouzaki

submission deadline 20 Aug 2026 | 5 articles | Viewed by 4014 | Submission Open

Keywords: immune cells; cytokines; immunomodulatory treatments; immune diseases; immune system

(This special issue belongs to the Section Molecular Immunology)

Advances in Colitis Research: Exploring Molecular Mechanisms and Immune Regulation

edited by

Jochen Mattner

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3957 | Submission Open

Keywords: colitis; inflammation; infection; autoimmunity; mucosal tolerance; colonization resistance; intestinal microbiota; host-microbe interactions

(This special issue belongs to the Section Molecular Immunology)

The Impact of Cancer–Immune Cell Crosstalk on Diagnosis, Prognosis and Treatment

edited by Fabricio Figueiro

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3952 | Submission Open

Keywords: protumoral immunity; anticancer immunity; crosstalk; tumor microenvironment; purinergic signaling; immune checkpoints; immunometabolism; extracellular vesicles; RNA communication

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antibiotics Science: Molecular Insights, Detection Strategies, Resistance Challenges and Interdisciplinary Applications

edited by

Lidia Magerusan

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3933 | Submission Open

Keywords: antibiotics; antibiotic molecular design and synthesis; antibiotic action mechanism; antibiotics resistance; environmental contamination; therapeutic monitoring; antibiotic sensing and detection; food and environmental safety

(This special issue belongs to the Section Molecular Microbiology)

Advances in Mass Spectrometry-Based Proteomics: From Biomarker Discovery to Translational Applications

edited by

Yanlong Ji

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3889 | Submission Open

Keywords: mass spectrometry; LC-MS method development; phosphoproteomics; glycoproteomics; biomarker discovery; multi-omics data integration

(This special issue belongs to the Section Biochemistry)

Environmental Pollutants Exposure and Toxicity

edited by

Tzveta Georgieva

submission deadline 20 Aug 2026 | 4 articles | Viewed by 3826 | Submission Open

Keywords: environmental pollutants exposure assessment; molecular methods; biomarkers; human safety; environmental safety

(This special issue belongs to the Section Molecular Toxicology)

Plant Responses to Heavy Metals: From Deficiency to Excess, 2nd Edition

edited by

Anna D. Kozhevnikova

and

Ilya Vladimirovich Seregin

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3795 | Submission Open

Keywords: heavy metals; deficiency; metal toxicity; metal (hyper-)accumulation; mechanisms of metal tolerance; metal transport; metal uptake; metal sequestration; metal homeostasis

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Conventional Tree Breeding: Integrating Phenotypic Selection, Genetic Gain, and Sustainable Forest Management

edited by

Jingli Yang

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3753 | Submission Open

Keywords: forest trees; genetic breeding; conventional tree breeding; forest management; forest tree varieties; modern molecular technology; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Inflammasomes

edited by

Roberto Negro

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3640 | Submission Open

Keywords: inflammasome; pyroptosis; innate immunity; cancer; neurodegenerative diseases; microbiota; gasdermin; ninjurin; drug screening; personalized treatments; multi-omics analysis

(This special issue belongs to the Section Molecular Immunology)

Ferroptosis and Cuproptosis: Mechanism and Crosstalk in Cancer, Neurodegeneration, and Metabolic Syndrome

edited by

Rosanna Squitti

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3616 | Submission Open

Keywords: ferroptosis; cuproptosis; Alzheimer's disease; colorectal cancer; neurodegeneration; metabolic syndrome; regulated cell death; iron metabolism; copper metabolism; psychiatric disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Molecular Imaging and Therapy

edited by

Xuyi Yue

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3599 | Submission Open

Keywords: molecular imaging; therapy; clinical translation; precision medicine; radiotheranostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Abiotic Stress Signaling in Plants: Focus on Atmospheric Stressors, 2nd Edition

edited by

Mateusz Labudda

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3586 | Submission Open

Keywords: abiotic stress; interactomics; gene expression regulation; kinases; oxidative stress; phytohormones; signaling, sugar sensing and signaling; transcription factors

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Synthesis and Study of Novel Bioactive Molecules

edited by

Adriana Georgieva Bakalova

and

Emiliya Demireva Cherneva

submission deadline 20 Aug 2026 | 4 articles | Viewed by 3561 | Submission Open

Keywords: organic compounds; metal complexes; bioactive molecules

(This special issue belongs to the Section Biochemistry)

Recent Advances in Regenerative and Anti-Aging Medicine

edited by

Takayuki Yoshimoto

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3537 | Submission Open

Keywords: induced pluripotent stem cells (iPSCs); mesenchymal stem cells (MSCs); platelet-rich plasma (PRP); placenta; organoid; secretome; exosome; senolytics; nicotinamide mononucleotide (NMN); nicotinamide adenine dinucleotide+ (NAD+)

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Molecular and Cellular Approaches to Tuberculosis Pathogenesis, Treatment and Prevention

edited by

Selvakumar Subbian

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3451 | Submission Open

Keywords: tuberculosis (TB); animal models of mycobacterium infections; molecular pathogenesis; host-directed therapy (HDT); nanoparticle drug delivery; vaccine development; cellular immunology; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Research in Probiotic Yeasts: Molecular Aspects

edited by

Maurizio Ciani

and

Francesca Comitini

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3401 | Submission Open

Keywords: probiotic yeasts; molecular mechanisms; mycocins active; compounds; functional compounds

(This special issue belongs to the Section Molecular Microbiology)

Molecular Genetics and Genomics of Aquatic Crustaceans

edited by

Xianhong Meng

, Falin Zhou and Lingbo Ma

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3329 | Submission Open

Keywords: genome sequencing; epigenomics; CRISPR/Cas9 gene editing; transcriptomics; gene expression profiling; genome-wide association studies (GWASs); quantitative trait loci (QTL) mapping; genomic selection; marker-assisted selection (MAS); molecular markers

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Plant Nematology Research

edited by

Sergei A. Subbotin

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3320 | Submission Open

Keywords: DNA barcoding; Molecular evolution; Genomes; Molecular systematics; Phylogenetics; Plant–nematode interactions; Transcriptomics

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Ion Channels in Health and Disease

edited by

Joohyun Nam

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3297 | Submission Open

Keywords: ion channel; molecular mechanisms; channelopathies; drug discovery; electrophysiology

(This special issue belongs to the Section Molecular Biology)

Novel Agents and Molecular Research in Multiple Myeloma

edited by

Claudio Cerchione

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3272 | Submission Open

Keywords: multiple myeloma; novel agents; target therapy; immunotherapy; bispecific antibodies; CAR-T

(This special issue belongs to the Section Molecular Oncology)

The Biogenesis, Structure, Function and Division of Plastids

edited by

Xiaomin Liu

and Li'na Yin

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3211 | Submission Open

Keywords: plastid; chloroplast; chlorophyll; endosymbiotic cyanobacteria; photosynthesis; genetic engineering

(This special issue belongs to the Section Biochemistry)

Advanced Research on Plant-Derived Products in the Service of Immune Regulation

edited by

Lyuba Dineva Miteva

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3197 | Submission Open

Keywords: plant bioactive compound; inflammation; immunity; cytokine; chronic disease

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insight into Natural Nutraceuticals for Cancer Chemoprevention

edited by

Jia-Feng Chang

and

Chih-Hsin Tang

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3097 | Submission Open

Keywords: natural nutraceuticals; cancer; cancer chemoprevention; natural compounds

(This special issue belongs to the Section Molecular Oncology)

Next Generation Sequencing in Human Diseases

edited by

Manuel Muro

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3076 | Submission Open

Keywords: NGS; single-cell analysis; metagenomics; forensic DNA analysis; precision medicine; genetic diagnostics; transplant monitoring; cell-free DNA; new allele and variant discovery

(This special issue belongs to the Section Molecular Informatics)

Molecular Studies on Wnt Signaling

edited by Katalin Mészáros

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2984 | Submission Open

Keywords: Wnt signaling pathway; inhibitor; cancer; treatment; drugs

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Embryo Developmental Potential: 2nd Edition

edited by

Jan Tesarik

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2969 | Submission Open

Keywords: embryo developmental potential; oocyte quality; sperm quality; non-invasive techniques; molecular biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Medicinal Plants and Natural Products: Second Edition

edited by

Teresa Leszczyńska

Barbara Borczak

and

Joanna Kapusta-Duch

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2953 | Submission Open

Keywords: medicinal plants; natural products; phytochemistry; bioactive substances; medicinal properties

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Research on Gut Microbiota in Health and Disease

edited by Li Cui

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2925 | Submission Open

Keywords: microbiota-host crosstalk; HMA models; microbial metabolites; gut–brain axis; translational microbiome

(This special issue belongs to the Section Molecular Microbiology)

Molecular Insights in Food Science: From Nutritional Value to Safety Evaluation

edited by

Mariachiara Bianco

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2891 | Submission Open

Keywords: nutraceutical; food safety; analytical methods; novel foods; food analysis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Epilepsy: Molecular Mechanisms, Neuroinflammation and Emerging Therapies

edited by

Karoly Orban-Kis

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2771 | Submission Open

Keywords: epilepsy; molecular targets; antiepileptic drug discovery; neuroinflammation; epileptogenesis; ion channels; pharmacoresistance; translational neuroscience

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oral Potentially Malignant Disorders and Oral Cancers: From Molecular Pathology to Therapeutic Approaches

edited by

Ana Caruntu

and Nicholas Kalavrezos

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2754 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; molecular mechanisms in oral cancer; detection of oral cancer; pathogenic mechanisms of oral cancer; immune system; translational oral cancer; microbiota oral cancer; therapy for oral cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular and Cellular Basis of Oral Immunology

edited by

Kenichi Kumagai

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2726 | Submission Open

Keywords: oral immunology; oral mucosa; immune tolerance; oral microbiome; oral diseases; periodontium; innate immunity; adaptive immunity

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 51-100 on page 2 of 62.

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