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Natural Products in Cancer Prevention and Treatment—Second Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 December 2025

Special Issue Editors


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Guest Editor
Department of Translational Medicine and Surgery, Section of General Pathology, School of Medicine and Surgery, Università Cattolica del Sacro Cuore, Largo F. Vito, 1-00168 Rome, Italy
Interests: cancer; nutrition; omega-3 fatty acids; antioxidants; phenolic compounds; inflammation; neurodegenerative diseases; nutrition; metabolic diseases
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Translational Medicine and Surgery, Section of General Pathology, School of Medicine and Surgery, Università Cattolica del Sacro Cuore, Largo F. Vito, 1-00168 Rome, Italy
Interests: cancer; nutrition; omega-3 fatty acids; antioxidants; phenolic compounds; inflammation; neurodegenerative diseases; metabolic diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cancer is a noncommunicable disease characterized by the uncontrolled proliferation of cells. It is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. Despite the use of innovative strategies such as targeted therapy and immunotherapy, in most cases, chemotherapy and radiation therapy are still the predominantly used forms of therapy. However, since they mainly act by damaging the DNA of rapidly dividing cancer cells, they also affect normal cells with high rates of proliferation, and can thus be associated with deleterious side effects. Moreover, drug resistance very frequently arises in treated patients, and targeted therapy and immunotherapy have also been associated with undesired side effects. As a result, there has been growing interest in new therapeutic approaches that have efficacious antineoplastic effects and are safe for normal cells. In recent years, natural compounds extracted from vegetables, fruits, and other dietary constituents, such as marine polyunsaturated fatty acids and minerals, have been widely studied for their potential to prevent cancer or for their use in combination with conventional or innovative anti-neoplastic therapies to improve their beneficial effects against cancer cells and reduce the concentration of drugs used.

 

This Special Issue will highlight the results of current preclinical and clinical studies focused on cancer and on anti-neoplastic therapeutic strategies involving natural products. In particular, it will provide an overview of novel molecular pathways targeted by natural products that are crucial for cancer treatments; we therefore invite researchers to contribute original articles and reviews on these topics.

 

Dr. Simona Serini

Dr. Gabriella Calviello

Guest Editors

Dr. Simona Serini
Dr. Gabriella Calviello
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • • natural products • cancer • therapeutic strategies • novel molecular pathways

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Published Papers

This special issue is now open for submission.
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