Microbial Fermentation: Advances in Synthetic Biology, Metabolic Engineering, and Biomanufacturing
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 52
Special Issue Editor
2. Science Center for Future Foods, Jiangnan University, Wuxi 214122, China
Interests: synthetic biology; metabolic engineering; cellular agriculture; precision fermentation; industrial microbiology; microbial cell factory; fermentation engineering
Special Issue Information
Dear Colleagues,
Microbial fermentation, as a cornerstone of industrial biotechnology, has long been a driving force in transforming raw biological materials into valuable products. In recent years, the convergence of synthetic biology, metabolic engineering, and advanced biomanufacturing techniques has revolutionized this field, unlocking unprecedented potential for generating new quality productive forces across various industries. Leveraging molecular-level advancements, such as DNA/protein engineering (e.g., CRISPR-based genome editing, enzyme design) or metabolic pathway regulation (e.g., genetic biosensors, cofactor engineering), researchers are now able to produce a wide range of high-value compounds—from foods and pharmaceuticals to sustainable chemicals and novel materials—with enhanced efficiency, sustainability, and scalability.
This Special Issue aims to showcase cutting-edge research at the intersection of synthetic biology, metabolic engineering, and microbial fermentation. We welcome original research articles and critical reviews that explore innovative strategies for chassis engineering (e.g., model/non-model microorganisms, extremophiles), advanced metabolic regulation techniques (e.g., dynamic pathway control, multi-omics integration), and sustainable biomanufacturing approaches (e.g., co-culture systems, waste valorization). Studies focusing on the molecular mechanisms underlying microbial productivity, as well as computational tools and high-throughput platforms for accelerating the design–build–test–learn (DBTL) cycle, are also encouraged.
Dr. Yaokang Wu
Guest Editor
Manuscript Submission Information
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Keywords
- microbial fermentation
- synthetic biology
- metabolic engineering
- biomanufacturing
- industrial biotechnology
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