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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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JAK/STAT Pathway in Stem Cell Biology

edited by Willis Li

submission deadline 25 Feb 2026 | Viewed by 99 | Submission Open

Keywords: JAK/STAT signaling; stem cell self-renewal; cellular differentiation; pluripotency; hematopoietic stem cells; signal transduction; cytokine receptors; transcriptional regulation; stem cell niche; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Chronic Inflammatory Sinonasal Diseases

edited by Santos Tiago Soares

submission deadline 25 Feb 2026 | Viewed by 83 | Submission Open

Keywords: chronic rhinosinusitis; nasal polyps; type 2 inflammation; sinonasal immunopathology; molecular pathways; host– microbiome interaction; precision medicine; upper airway disease; translational research

(This special issue belongs to the Section Molecular Immunology)

Angiotensin II in Cardiac Fibrosis and Heart Failure

edited by Argyrios S. Ntalianis

submission deadline 25 Feb 2026 | Viewed by 76 | Submission Open

Keywords: angiotensin II; aldosterone; molecular genetics; cardiac remodeling; cardiac fibrosis; cardiomyopathy; heart failure

(This special issue belongs to the Section Molecular Pharmacology)

Recent Research on Natural Compounds in Cancer Treatment and Prevention

edited by

Katarzyna Lubecka-Gajewska

submission deadline 25 Feb 2026 | Viewed by 75 | Submission Open

Keywords: natural compounds; bioactive phytochemicals; anticancer therapy; chemoprevention

(This special issue belongs to the Section Molecular Oncology)

Molecular Pathophysiology and Treatments of Diabetes

edited by

Carlo Acierno

submission deadline 26 Feb 2026 | Viewed by 191 | Submission Open

Keywords: diabetes mellitus; molecular pathophysiology; insulin resistance; beta-cell dysfunction; chronic inflammation; epigenetics; metabolic syndrome; SGLT2 inhibitors; GLP-1 receptor agonists; gut microbiota

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Application of Mass Spectrometry and Chromatography in Biomedicine: 2nd Edition

edited by

Giovanni Ventura

submission deadline 27 Feb 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: mass spectrometry; chromatography; LC-MS; GC-MS; biomarker discovery; pharmaceuticals; metabolomics; proteomics; lipidomics

(This special issue belongs to the Section Molecular Biophysics)

Recent Prospects in Neurons

edited by

Tam Thanh Quach

submission deadline 27 Feb 2026 | Viewed by 122 | Submission Open

Keywords: DNA damage/repair; genetic/epigenetic; 3D genomic; global transcriptome analysis; transgenic animals; neuron polarization/genesis/network; neuro-developmental/psychiatric diseases; brain structures; intelligence/intellectual disability

(This special issue belongs to the Section Molecular Neurobiology)

Current Trends in Nanophotonics and Molecular-Scale Light Control

edited by Mitradeep Sarkar

submission deadline 27 Feb 2026 | Viewed by 112 | Submission Open

Keywords: nanophotonics; light– matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics

(This special issue belongs to the Section Molecular Nanoscience)

Lung Diseases Molecular Pathogenesis and Therapy

edited by

Kazufumi Nakamura

submission deadline 28 Feb 2026 | 6 articles | Viewed by 19942 | Submission Open

Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Rare Diseases Biomarkers: 2nd Edition

edited by

Andrea Bernini

submission deadline 28 Feb 2026 | 5 articles | Viewed by 18733 | Submission Open

Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Cell Signaling Pathways and Signal Transduction

edited by Katsuhiko Muraki and

Susumu Ohya

submission deadline 28 Feb 2026 | 6 articles | Viewed by 16675 | Submission Open

Keywords: Ca2+ signaling; transcriptional and post-transcriptional pathways; growth factors; second messengers; cell metabolism; cell senescence; protein phosphorylation/dephosphorylation; membrane trafficking; cell proliferation; differentiation; and apoptosis; cytokine/chemokine signaling

(This special issue belongs to the Section Biochemistry)

Drug Discovery Based on Natural Products

edited by Woo-kyung Kim

submission deadline 28 Feb 2026 | 7 articles | Viewed by 13857 | Submission Open

Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies

(This special issue belongs to the Section Molecular Pharmacology)

Plant–Microbe Interactions: 2nd Edition

edited by Jian Jin

submission deadline 28 Feb 2026 | 6 articles | Viewed by 9082 | Submission Open

Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes

(This special issue belongs to the Section Molecular Plant Sciences)

Anti-Cancer Drugs: Natural Products, Synthetic Compounds and Potential Pharmacological Effects and Applications

edited by Kaiqun Ren and Hui Zou

submission deadline 28 Feb 2026 | 3 articles | Viewed by 8918 | Submission Open

Keywords: cancer; natural product; synthetic compounds; mechanism; structural modification; pharmacological action

(This special issue belongs to the Section Molecular Pharmacology)

Oral Soft Tissue Repair and Oral Diseases: 2nd Edition

edited by

Jacek Matys

submission deadline 28 Feb 2026 | 4 articles | Viewed by 6624 | Submission Open

Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; implant dentistry

(This special issue belongs to the Section Molecular Biology)

Blood Cells in Human Health and Disease

edited by Leonid Livshits

submission deadline 28 Feb 2026 | 4 articles | Viewed by 6195 | Submission Open

Keywords: red blood cell; RBC membrane; RBC biophysical properties; RBC rheology; RBC mechanical properties; RBC membrane vesiculation; RBC clearance; RBC in diabetes; hemoglobinopathies; RBC storage TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Biochemistry)

The Molecular Role of Platelets in Human Diseases

edited by

Lukasz Szarpak

and

Michał Pruc

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6151 | Submission Open

Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis

(This special issue belongs to the Section Molecular Biology)

Molecular Imaging for Cancer Theranostics

edited by

Hak Soo Choi

and Kai Bao

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5751 | Submission Open

Keywords: molecular imaging; cancer theranostics; precision medicine; targeted therapy; diagnostic imaging; theranostic agents; multimodal imaging; molecular probes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Amyloid Aggregation and Its Inhibition: Implementing Insights from Physiological Conditions

edited by

Andrius Sakalauskas

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4753 | Submission Open

Keywords: protein aggregation; amyloid; physiological conditions; aggregation inhibition; neurodegenerative diseases; amyloidosis

(This special issue belongs to the Section Molecular Neurobiology)

Bioinformatics of Gene Regulations and Structure–2025

edited by

Yuriy L. Orlov

Anastasia Anashkina

and

Nikolay A. Kolchanov

submission deadline 28 Feb 2026 | 6 articles | Viewed by 4266 | Submission Open

Keywords: gene expression regulation; bioinformatics and systems biology; NGS data analysis of gene expression; ncRNA networks; computer genomics of model organisms; fundamental biomedicine model; regulatory gene networks; AI tools in bioinformatics

(This special issue belongs to the Section Molecular Informatics)

Anti-Inflammatory and Anti-Oxidant Effects of Extracts from Plants

edited by

Sheila Leone

and

Lucia Recinella

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4128 | Submission Open

Keywords: oxidative stress; inflammation; herbal extracts

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Microbiomes in Human Health and Disease

edited by

Andreas Burkovski

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4126 | Submission Open

Keywords: microbiome; dysbiosis; commensal bacteria; pathobiont; metabolites; immune modulation; nutrient metabolism; barrier function; health and disease

(This special issue belongs to the Section Molecular Microbiology)

New Advances in Nanomedicine Innovation in Cancer Treatment

edited by Tijani Gharbi

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4057 | Submission Open

Keywords: nanotechnology; nanomedicine; radiotherapy; theragnostic; antibody– drug conjugates (ADCs); drug delivery; radiopharmaceutical; gold nanoparticles; nanoparticle– biomolecule conjugate

(This special issue belongs to the Section Molecular Nanoscience)

Network Pharmacology: An Emerging Field in Drug Discovery (2nd Edition)

edited by

Weiwei Han

submission deadline 28 Feb 2026 | 5 articles | Viewed by 3765 | Submission Open

Keywords: network pharmacology; machine learning; databases; drug discovery; computer-aided drug design (CADD); data mining

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into the Molecular Pathogenesis of Myeloproliferative Neoplasms

edited by

Laura Georgiana Necula

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2817 | Submission Open

Keywords: myeloproliferative neoplasms; molecular diagnostic; targeted therapy; biomarkers; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Liquid Biopsies in Oncology—3rd Edition

edited by

Sandra V. Fernandez

and

Carmela Paolillo

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2759 | Submission Open

Keywords: precision oncology; personalized therapy; cancer biomarkers; liquid biopsy; biological fluids; circulating molecules; circulating tumor cells; CTCs; ctDNA; ctRNA; cell-free DNA; cfDNA; NGS; circulating miRNAs; exosomes; extracellular vesicles

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition

edited by

Hui Qiao

and Hongtuo Fu

submission deadline 28 Feb 2026 | 4 articles | Viewed by 2301 | Submission Open

Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture

(This special issue belongs to the Section Molecular Biology)

Viral Infections: Physiology, Pathophysiology, Pathogenesis, Diagnosis and Treatment, 2nd Edition

edited by

Barbara Bażanów

and Dominika Marta Stygar

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2254 | Submission Open

Keywords: viral infections; virus mutations; molecular diagnostic methods; antiviral drugs/preparations; viral diseases; physiological mechanisms

(This special issue belongs to the Section Molecular Microbiology)

Advances in Molecular Biomarkers in Cancer and Metabolic Diseases

edited by

José Antonio Morales-González

and

Angel Morales-González

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2001 | Submission Open

Keywords: biomarkers; cancer; metabolic disease; diagnosis; prognosis; treatment

(This special issue belongs to the Section Molecular Biology)

Damage to Plants and Microorganisms Caused by Heavy Metal Toxicity

edited by

Xiaomeng Chen

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1796 | Submission Open

Keywords: metal; oxidative stress; stress response; molecular function; gene regulation; metabolic regulation; signaling pathway

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Natural Antioxidants in Human Health and Diseases

edited by

Eman M. Othman

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1627 | Submission Open

Keywords: oxidative stress and diseases; antioxidants; natural products

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Trends in Diabetes, Hypertension and Cardiovascular Diseases: 4th Edition

edited by

Yutang Wang

and

Dianna Magliano

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1562 | Submission Open

Keywords: cardiovascular disease; myocardial infarction; stroke; transient ischemic attack; hypertension; diabetes mellitus; atherosclerosis; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Network Pharmacology

edited by

Mi Hye Kim

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1518 | Submission Open

Keywords: network pharmacology; traditional medicine; drug discovery; computational biology; molecular mechanisms; protein– protein interaction; enrichment analysis; herb– compound– gene network

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Diagnostics and Therapeutic Targets in Bladder Cancer (Second Edition)

edited by

Hideki Furuya

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1471 | Submission Open

Keywords: non-muscle invasive bladder cancer; muscle-invasive bladder cancer; metastatic bladder cancer; diagnostic biomarkers; therapeutic targets; early detection; progression biomarkers; liquid biopsy; genomic profiling; proteomics; metabolomics; imaging biomarkers; multi-omics; targeted therapy; immunotherapy; antibody– drug conjugates; DNA damage response; tumor microenvironment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cardiovascular and Metabolic Pharmacology

edited by

Alma Martelli

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1455 | Submission Open

Keywords: cardiovascular pharmacology; metabolic pharmacology; hypertension; diabetes; obesity; atherosclerosis; hyperlipidemias; heart failure

(This special issue belongs to the Section Molecular Pharmacology)

Melanoma: Molecular Diagnosis and Treatment

edited by

Teresa Lettini

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1417 | Submission Open

Keywords: molecular pathology; melanoma; skin cancer; molecular pathway; dermatopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovative Technologies in the Study and Understanding of Colorectal Tumorigenesis: Challenges and Opportunities

edited by

Paola Sena

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1348 | Submission Open

Keywords: colorectal cancer; genetic analysis; gut microbiome; tumor; circulating components; medicine; immunotherapy; proteomics

(This special issue belongs to the Section Molecular Oncology)

The Differential Role of B Cells in Autoimmune Diseases: From Autoantibodies to Antigen Presentation

edited by

Markus C. Kowarik

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: autoantibodies; B cells; antigen presentation; B cell functions; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Genetic Advances in Neurobiology of Health and Disease

edited by

Efthimios M. C. Skoulakis

and Katerina Papanikolopoulou

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1309 | Submission Open

Keywords: genomics; proteins; proteomics; signaling

(This special issue belongs to the Section Molecular Neurobiology)

Immunity in Neurodegenerative Diseases: Systemic Immune Imbalance, Neuroinflammation, and Beyond—2nd Edition

edited by

Ivana Munitic

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1135 | Submission Open

Keywords: neurodegeneration; CNS immunosurveillance; neuroinflammation; neuroimmune axis; glia; T cells; phagocytosis; immunomodulation; autoimmunity; immunodeficiency

(This special issue belongs to the Section Molecular Neurobiology)

New Advances in Amyotrophic Lateral Sclerosis

edited by

Vacchiano Veria

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1131 | Submission Open

Keywords: genetics and epigenetics; biomarkers; nutrition and metabolism; TDP-43 pathology; advanced model of ALS

(This special issue belongs to the Section Molecular Neurobiology)

Oral Diseases: Molecular Research and Novel Therapy

edited by

I-Ta Lee

submission deadline 28 Feb 2026 | Viewed by 1131 | Submission Open

Keywords: oral diseases; molecular mechanisms; inflammation and immunity; redox signalling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Trends and Future Directions in Antimicrobial Peptide Research

edited by

Sara Elsa Aita

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1096 | Submission Open

Keywords: antimicrobial peptides (AMPs); host defense; structure-function; antimicrobial agents; biomedical applications; antibiotic alternatives; antibiotic resistance

(This special issue belongs to the Section Molecular Biology)

Molecular Advances and Views in Triple-Negative Breast Cancer

edited by

Ioannis Boutas

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1040 | Submission Open

Keywords: breast cancer; molecular biology; personalized medicine; triple-negative breast cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology of Foodborne Pathogens: Genomics, Resistance, and New Perspectives

edited by

Joanna Gajewska

submission deadline 28 Feb 2026 | Viewed by 979 | Submission Open

Keywords: foodborne pathogens; antibiotic resistance; virulence factor; virulence genes; gene expression; bioinformatics; whole geomic sequencing

(This special issue belongs to the Section Molecular Microbiology)

Oxidative-Stress in Human Health and Diseases

edited by

Ramoji Kosuru

submission deadline 28 Feb 2026 | 1 articles | Viewed by 879 | Submission Open

Keywords: oxidative stress; ROS; redox signaling; metabolic adaptation; oxidative homeostasis; endothelial dysfunction

(This special issue belongs to the Section Biochemistry)

Advanced Functionalization of Biopolymers and Bio-Oligomers for Precision Therapeutics

edited by

Dayong Wang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 843 | Submission Open

Keywords: precision therapeutics; biopolymers; drug delivery; biopharmaceuticals; pharmacology

(This special issue belongs to the Section Materials Science)

Molecular and Cellular Biology of Germ Cells

edited by

Anna Tabęcka-Łonczyńska

submission deadline 28 Feb 2026 | 1 articles | Viewed by 821 | Submission Open

Keywords: germ cell development; meiosis; epigenetic regulation; autophagy; mitochondrial dynamics; infertility; reproductive medicine; germ cell tumors; steroidogenesis; endocrine disrupting chemicals; reproductive toxicity

(This special issue belongs to the Section Molecular Biology)

Pathophysiology and Molecular Mechanisms of Cardiovascular, Cardiometabolic, and Cardiorenal Diseases

edited by

Carmine Savoia

submission deadline 28 Feb 2026 | 1 articles | Viewed by 793 | Submission Open

Keywords: heart failure; cardiorenal syndrome; oxidative stress; inflammation; endothelial dysfunction; fibrosis and remodeling; mitochondrial function and energy metabolism; insulin resistance; epigenetics and microRNAs; biomarkers and precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Marine Natural Products as a Source of Therapeutics—Recent Trends

edited by

Komal Anjum

submission deadline 28 Feb 2026 | 1 articles | Viewed by 792 | Submission Open

Keywords: marine natural products; marine-associated microbes; antimicrobial drug; antibiotics; marine-derived peptides; anti-inflammatory; molecular pharmacology; targeted therapies; extraction

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 1101-1150 on page 23 of 67.

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