The Differential Role of B Cells in Autoimmune Diseases: From Autoantibodies to Antigen Presentation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 21
Special Issue Editor
Interests: neuroimmunology; multiple sclerosis; neuromyelitis optica spectrum disease; B cells; oncoimmunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
B cells play multifaceted roles in the pathogenesis of autoimmune diseases, extending far beyond their well-known function as producers of pathogenic autoantibodies. Recent advances highlight that B cells contribute not only through antibody secretion but also as potent antigen-presenting cells, influencing T cell activation and modulating immune responses. This Special Issue explores the spectrum of B cell activities in autoimmunity, delineating how factors such as B cell subtypes, cytokine secretion, and their interactions within tissue microenvironments shape disease onset and progression. The topics covered span a broad range of autoimmune diseases, from those encountered in internal medicine to neurological conditions, underscoring the central importance of B cells across clinical disciplines.
Dr. Markus C. Kowarik
Guest Editor
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Keywords
- autoantibodies
- B cells
- antigen presentation
- B cell functions
- autoimmunity
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