Bioinformatics of Gene Regulations and Structure–2025
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 8
Special Issue Editors
Interests: computer genomics; bioinformatics; digital medicine (e-Health); gene expression regulation; ChIP-seq
Special Issues, Collections and Topics in MDPI journals
Interests: DNA; protein; recognition; affinity; specificity; selectivity; local structure; pattern; motif; interaction energy
Special Issues, Collections and Topics in MDPI journals
Interests: bioinformatics; systems biology; genetics; genomics; gene networks
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This is a Special Issue collecting research manuscripts and reviews on genetics and bioinformatics on the topic of gene expression regulation from the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (ICG SB RAS) in Novosibirsk, Russia (https://www.icgbio.ru/), discussed at the “Bioinformatics of Genome Regulation and Structure/Systems Biology” (BGRS\SB) conference series. BGRS is a traditional biannual conference series in Novosibirsk that started in 1998 and that gathers scientists, bioinformaticians, medical doctors, and geneticists. Gene expression regulation at the transcriptional level is a key topic of this journal issue.
We have already organized several successful Special Issues on the bioinformatics of gene expression, including "Molecular Mechanisms of Gene Expression: “Bioinformatics of Gene Regulations and Structure”" (https://www.mdpi.com/journal/ijms/special_issues/Bioinformatics_Genomics) and "Bioinformatics of Gene Regulations and Structure - 2022" (https://www.mdpi.com/journal/ijms/special_issues/Bioinformatics_Gene), and then a series of topic issues on the medical applications of the bioinformatics of gene expression; see the links below.
In the research perspectives part of this Special Issue, we will focus on bioinformatics and systems biology approaches to genomics and biotechnology problems. The central problems include the analysis of the molecular mechanisms of gene expression regulation, analysis of transcription regulation by protein transcription factors (TFs), regulatory gene network interaction analysis, and applications of modern AI tools in bioinformatics.
Topics of interest for this Special Issue include the following:
- Analysis of gene expression regulation;
- Applications of bioinformatics to omics technologies;
- Non-coding RNA in gene expression regulation
- Gene networks and associative networks analysis;
- Protein structure analysis and biophysical models;
- Interdisciplinary research in computational genomics of model organisms—plants, animals, and bacteria;
- Systems biology approaches for gene expression analysis, including machine learning and AI.
The BGRS conference series has its own history of initiating successful Special Issues on bioinformatics with IJMS:
- https://www.mdpi.com/journal/ijms/special_issues/Medical_Genetics_Bioinformatics (2019);
- https://www.mdpi.com/journal/ijms/special_issues/Medical_Genetics_Bioinformatics_2 (2020);
- https://www.mdpi.com/journal/ijms/special_issues/Medical_Genetics_2021 (2021);
- https://www.mdpi.com/journal/ijms/special_issues/Medical_Genetics_2022 (2022);
- https://www.mdpi.com/journal/ijms/special_issues/Plant_Biotechnology (2022);
- https://www.mdpi.com/journal/ijms/special_issues/PlantBi_Biology (2023);
- "New Sights into Bioinformatics of Gene Regulations and Structure" (2024);
- 25th Anniversary of Bioinformatics of Genome Regulation and Structure Conference Series (2024);
- Plant Biology and Biotechnology: Focus on Genomics, Bioinformatics and AI (2025).
Research on bioinformatics topics is in high demand at IJMS. We welcome novel research on bioinformatics education that extends the discussion beyond the frames of the BGRS conference series.
Prof. Dr. Yuriy L. Orlov
Dr. Anastasia Anashkina
Prof. Dr. Nikolay A. Kolchanov
Guest Editors
Manuscript Submission Information
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Keywords
- gene expression regulation
- bioinformatics and systems biology
- NGS data analysis of gene expression
- ncRNA networks
- computer genomics of model organisms
- fundamental biomedicine model
- regulatory gene networks
- AI tools in bioinformatics
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