Angiotensin II in Cardiac Fibrosis and Heart Failure
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 25 February 2026 | Viewed by 59
Special Issue Editor
Interests: heart failure; cardiomyopathies; coronary artery disease; interventional cardiology; structural heart disease percutaneous interventions; heart failure percutaneous interventions
Special Issue Information
Dear Colleagues,
In this Special Issue of the International Journal of Molecular Sciences, “Angiotensin II in Cardiac Fibrosis and Heart Failure”, my colleagues and I will thoroughly review the current literature, reporting available clinical and experimental data that link angiotensin II with cardiac fibrosis and discussing potential pathophysiological mechanisms underlying the transition from cardiac fibrosis to heart failure.
In particular, we aim to provide insights into the molecular mechanisms and signaling pathways triggered by angiotensin II that can induce cardiac fibrosis. We will also describe alterations in molecular biology and genetics that affect the structure and/or function of genes, which in turn influence cardiac function and anatomy (i.e., the size and the shape of the heart). This maladaptive process, known as cardiac remodeling, is associated with poor quality of life, adverse cardiovascular events, and unfavorable prognosis.
Dr. Argyrios S. Ntalianis
Guest Editor
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Keywords
- angiotensin II
- aldosterone
- molecular genetics
- cardiac remodeling
- cardiac fibrosis
- cardiomyopathy
- heart failure
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