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Molecular and Cellular Biology of Germ Cells

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 99

Special Issue Editor


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Guest Editor
Department of Biotechnology and Cell Biology, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225 Rzeszow, Poland
Interests: pharmacology; medical science; neuroscience; cognition; depression; anxiety
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Special Issue Information

Dear Colleagues,

Germ cell development is a fundamental biological process ensuring the transmission of genetic and epigenetic information across generations. Recent progress in molecular biology, imaging, and omics technologies has shed new light on germ cell specification, proliferation, meiosis, DNA repair, mitochondrial dynamics, and autophagy. At the same time, increasing evidence highlights the vulnerability of germ cells to environmental stressors, including endocrine-disrupting chemicals that may impair fertility and reproductive health.

This Special Issue aims to provide an interdisciplinary platform for presenting recent discoveries on germ cell biology and its clinical implications. Submissions may include studies addressing molecular regulation, cellular stress responses, epigenetic control, and the impact of environmental and pharmacological factors on germ cell function. We particularly welcome contributions linking basic science with translational applications in infertility treatment, regenerative medicine, and reproductive toxicology.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Molecular mechanisms of germ cell specification and differentiation;
  • Regulation of meiosis and DNA repair in germ cells;
  • Mitochondrial function, dynamics, and quality control in germ cells;
  • Role of autophagy and cellular stress responses;
  • Epigenetic regulation and transgenerational inheritance;
  • Impact of endocrine-disrupting chemicals and xenobiotics on germ cell development;
  • Germ cell tumors and clinical implications in reproductive medicine.

Dr. Anna Tabęcka-Łonczyńska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • germ cell development
  • meiosis
  • epigenetic regulation
  • autophagy
  • mitochondrial dynamics
  • infertility
  • reproductive medicine
  • germ cell tumors
  • steroidogenesis
  • endocrine disrupting chemicals
  • reproductive toxicity

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Published Papers

This special issue is now open for submission.
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