International Journal of Molecular Sciences

The Role of Melatonin in Plants: 3rd Edition

edited by

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1667 | Submission Open

Keywords: melatonin; phytomelatonin; plants; seed germination; seasonal and circadian rhythms; flowering; fruit ripening; plant immunity; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Heart Failure: New Paradigms in Molecular Pathology and Mechanistic Regulation

edited by Carlo Domenico Maida and Mario Daidone

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1666 | Submission Open

Keywords: heart failure; molecular mechanisms; immune regulation; inflammation; microRNA; biomarkers; cardio–renal axis; translational medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Parkinson’s Disease: Current Insights and Future Directions

edited by Laura Adalid-Peralta

submission deadline 30 Nov 2026 | Viewed by 1663 | Submission Open

Keywords: Parkinson’s disease; neurodegenerative mechanisms; genetic susceptibility; alpha-synuclein aggregation; neuroinflammation; mitochondrial dysfunction; oxidative stress; autophagy–lysosomal pathway; gut–brain axis; microbiome dysbiosis

(This special issue belongs to the Section Molecular Neurobiology)

Intron Retention (IR): RNA Processing, Post-Transcriptional Regulation in Stress Response, Genomic Function

edited by

Norihiro Okada

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1594 | Submission Open

Keywords: intron retention; alternative splicing; RNA processing; stress response; post-transcriptional regulation; nuclear export; nonsense-mediated decay; RNA surveillance; RNA-binding proteins; long-read sequencing; single-cell transcriptomics; biomarker; systems biology; disease mechanisms; proteostasis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Research on Esophageal Cancer

edited by

Antônio Palumbo Júnior

and Nathalia de Oliveira Meireles Da Costa

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1593 | Submission Open

Keywords: esophageal carcinogenesis; esophageal cancer prevention and diagnosis; molecular profiling of esophageal cancer; microenvironment and metastasis of esophageal cancer; molecular therapy approaches in esophageal cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Skeletal Muscle Adaptation

edited by

Michele Salanova

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1535 | Submission Open

Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mesenchymal Stem Cells: Evolving Concepts and Their Functions in Regeneration and Repair Processes

edited by Rodrigo Somoza

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1524 | Submission Open

Keywords: mesenchymal stem cells; medicinal signaling cells; pericytes; immunomodulation; paracrine signaling; regenerative medicine; perivascular niche; extracellular vesicles; allogeneic cell therapy

(This special issue belongs to the Section Molecular Biology)

The Balance of the Microbiome and Human Health: A Molecular Perspective

edited by

Xinyi Yang

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1522 | Submission Open

Keywords: host–microbiome interactions; molecular mechanisms; metabolite signaling; multi-omics integration; genome-scale metabolic models (GEMs); machine learning; spatial microbiome; precision intervention; microbiome–drug interaction; personalized nutrition

(This special issue belongs to the Section Molecular Microbiology)

Molecular Biomarkers in Mood Disorders

edited by Lionella Palego and

Valerio Dell’Oste

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1515 | Submission Open

Keywords: mood disorders; etiopathogenesis; genetics/epigenetics; RNA analyses; neuroendocrinology; inflammation; molecular markers

(This special issue belongs to the Section Molecular Neurobiology)

Theoretical and Computational Chemistry: New Insights into Molecular Modeling and Design

edited by

Alejandro Morales-Bayuelo

and

Cleber Melo-Filho

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1513 | Submission Open

Keywords: theoretical chemistry; computational chemistry; molecular modeling; quantum chemistry; density functional theory (DFT); molecular dynamics (MD); molecular structure prediction; reaction mechanism modeling

(This special issue belongs to the Section Molecular Informatics)

Bioactive Compounds Targeting Metabolic Disorders: Molecular Mechanisms and Translational Applications

edited by

Dongmin Liu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1512 | Submission Open

Keywords: bioactive compounds; obesity; type 2 diabetes; insulin resistance; adipose tissue; gut microbiota; inflammation; oxidative stress; nutraceuticals; molecular nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research of Cardiovascular Disease

edited by

John A. St. Cyr

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1468 | Submission Open

Keywords: myocardium; metabolism; ischemia; function; integrity; cardiovascular; disease; infarction; failure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Advances in the Pathophysiology and Treatment of Multiple Sclerosis and Related Disorders

edited by Natalia Szejko and

Sara Samadzadeh

submission deadline 30 Nov 2026 | Viewed by 1446 | Submission Open

Keywords: multiple sclerosis; MS; central nervous system; pathophysiology; immunological system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Beyond the Scale: Metabolic Pathways and the Pathophysiology of Obesity

edited by

Marika Crescenzi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1444 | Submission Open

Keywords: meta-inflammation; adipokynes; purinergic system; MASH; WAT; NAMs; gut microbiome

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Role of Mitochondria in Renal and Cardiac Diseases

edited by

Ana Karina Aranda-Rivera

and

José Pedraza Chaverri

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1440 | Submission Open

Keywords: kidney and cardiac diseases; mitochondria; mitochondrial impairment; cardiorenal syndrome; mitochondrial proteins; dynamics; bioenergetics

(This special issue belongs to the Section Molecular Biology)

New Advances in Xenobiotic Toxicology

edited by Marcelo Arbo

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1379 | Submission Open

Keywords: xenobiotics; toxicity tests; biotransformation; drug effects; signal transduction; environmental pollutants; chemically induced- injury; toxicogenomics; biomarkers; risk assessment

(This special issue belongs to the Section Molecular Toxicology)

Gut–Brain Axis: Pathophysiological Mechanisms in Neurological Disorders and Metabolic Diseases

edited by

Giovanna Traina

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1375 | Submission Open

Keywords: gut–brain axis; intestinal microbiota; mood diseases; immune system; microbial molecules; behavior; metabolic diseases; signaling pathways; inflammation; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Nutrigenomics, Pharmacogenomics and Personalized Medicine: Integrating Omics Sciences, Advanced Diagnostics and Precision Health Strategies

edited by

Ana María Sifuentes Rincón

and

David Guillermo Pérez-Ishiwara

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1329 | Submission Open

Keywords: nutrigenomics and pharmacogenomics; presicion nutrition; individualized dietary interventions; personalized medicine; biomarkers; precision health devices

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research of Gastrointestinal Disease, 3rd Edition

edited by

Ainsley Robinson

and

Kulmira Nurgali

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1326 | Submission Open

Keywords: gastrointestinal health; gastrointestinal disorders; gastrointestinal disease; gastrointestinal homeostasis; molecular targets; mechanisms; pathways; molecular markers; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Bacterial Multidrug Resistance

edited by

Andrea Marino

and

Stefano Stracquadanio

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1315 | Submission Open

Keywords: antimicrobial resistance; multidrug resistance; horizontal gene transfer; biofilms; molecular epidemiology; efflux pumps

(This special issue belongs to the Section Molecular Microbiology)

The Circadian Clock in Aging and Age-Related Diseases

edited by

Gianluigi Mazzoccoli

,

Tommaso Colangelo

and

Giovanni Damiani

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1314 | Submission Open

Keywords: circadian timing system; molecular clockwork; rhythmicity; biological clock; aging inflammation; metabolism; endoplasmic reticulum stress

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Breast Cancer Immunology and Immunotherapy

edited by Tamara Gulić

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1268 | Submission Open

Keywords: breast cancer; immunology; tumor microenvironment; immunotherapy tumor infiltrating lymphocytes; innate immunology; immune-checkpoint inhibitors; immunotherapy; biomarkers; targeted therapies

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of Adipose Tissue Dysfunction

edited by

Stefano Quarta

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1248 | Submission Open

Keywords: adipose tissue dysfunction; adipogenesis; immunometabolism and adipokines; mitochondrial dysfunction; extracellular vesicles; fibrosis and ECM remodeling; lipid metabolism; browning and beigeing; metabolic biomarkers and therapeutic targets; adipose-derived stem cells

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

From Pathogenic Mechanisms to Therapy in Gynecological Diseases

edited by

David B. Alexander

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1234 | Submission Open

Keywords: malignant gynecological diseases; screening for gynecological cancers; benign gynecological conditions; screening for benign gynecological diseases; endometriosis; polycystic ovaries syndrome; ovarian cysts; uterine fibroids; leiomyomas; adenomyosis; pelvic inflammatory disease; vaginitis; vaginal dysbiosis; treatment targets for gynecological diseases

(This special issue belongs to the Section Molecular Oncology)

Functional Genomics and Computational Biology of Horticultural Plants

edited by

Claudio Pugliesi

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1211 | Submission Open

Keywords: transcriptomics; computational model; genome editing; GWAS; multi-omics; NGS technologies; MAS; genomic selection; mutagenesis; RNA-silencing

(This special issue belongs to the Section Molecular Plant Sciences)

Musculoskeletal Development and Skeletal Pathophysiologies, 3rd Edition

edited by

Elizabeth W. Bradley

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1185 | Submission Open

Keywords: musculoskeletal development; growth plate; endochondral ossification; intramembranous ossification; osteoporosis; osteoarthritis; bone; cartilage; osteoblast; osteoclast; chondrocyte

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition

edited by

Noemi Monti

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1172 | Submission Open

Keywords: metastasis; fibrosis; tumor microenvironment; molecular pathways; EMT reversion

(This special issue belongs to the Section Molecular Biology)

Integrative Mechanisms and Translational Outcomes of Excitatory–Inhibitory Neurotransmission Switching in Neuropathic Pain

edited by

Poppy Schoenberg

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1165 | Submission Open

Keywords: neuropathic pain; excitatory–inhibitory balance (E/I balance); neurotransmission switching; microglia; spinal dorsal horn; circuit remodeling; translational biomarkers; computational modeling; glutamatergic signaling; neuromodulation

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Zoonoses and Vector-Borne Diseases

edited by Ravi Durvasula

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1158 | Submission Open

Keywords: malaria; leishmaniasis; soil-transmitted helminths; one health; cryptosporidiosis; trypanosomiasis; mosquito-borne infections; arboviral diseases; paratransgenesis; drug discovery; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanisms of Genotoxicity Induced by Environmental Mutagens—Focus on Nanoparticles and Micro/Nanoplastics

edited by

Ricard Marcos

and Susana Pastor

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1125 | Submission Open

Keywords: genotoxicity; DNA damage; chromosome damage; DNA repair; comet assay; micronucleus assay; mechanisms; environmental pollutants; micro/nanoplastics; nanoparticles

(This special issue belongs to the Section Molecular Toxicology)

Unraveling the Molecular Landscape of Primary Brain Tumors

edited by

Giuseppe Lombardi

, Francesco Pasqualetti and Tamara Ius

submission deadline 30 Nov 2026 | Viewed by 1111 | Submission Open

Keywords: primary brain tumors; molecular oncology; glioma; glioblastoma; biomarkers; targeted therapy; epigenetics; tumor microenvironment; genomic profiling; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Microbial Enzymes: Molecular Structure and Mechanism

edited by Rui Ma

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1085 | Submission Open

Keywords: microbial enzymes; biocatalytic application; molecular enzymology

(This special issue belongs to the Section Molecular Biology)

Radiofrequency on Human Health: A Molecular Perspective

edited by

Mariateresa Allocca

and Valentina Peluso

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1083 | Submission Open

Keywords: radiofrequency electromagnetic field; bioelectromagnetics; health effects; biological effects; molecular mechanisms; interaction mechanisms; electromagnetic risk assessment; biomedical application

(This special issue belongs to the Section Molecular Biophysics)

Molecular Mechanisms of Neuropsychiatric Disorders

edited by Marina Mitrovic,

Gvozden Rosic

and

Dragica Selakovic

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1061 | Submission Open

Keywords: neurological disorders; psychiatric disorders; pathophysiological mechanisms; apoptosis; oxidative stress; inflammation; neurotransmitters; neurotrophins; pharmacotherapy; transcranial stimulation

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Pharmacology and Biological Activities of Natural and Derivatives Bioactive Compounds

edited by

Rafał Hałasa

and

Katarzyna Turecka

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1054 | Submission Open

Keywords: molecular pharmacology; therapeutic potential; natural compounds; synthetic derivatives of natural compounds; biological activity; mechanism of action; molecular docking; anticancer; antimicrobial; pharmacokinetics; pharmacodynamics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Chronic Kidney Disease: Underlying Molecular Mechanisms—2nd Edition

edited by

Luís Belo

and

Márcia Carvalho

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1054 | Submission Open

Keywords: chronic kidney disease; molecular mechanisms; toxicity mechanisms; inflammation; environmental factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Regulation of Plant Tolerance to Saline, Alkali, and Combined Stresses

edited by

Lixin Li

and Yiming Zhang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1031 | Submission Open

Keywords: saline–alkali stress; plant's environmental adaptation mechanisms; metabolism and secondary metabolism; signal transduction; plant–microorganism interaction; omics

(This special issue belongs to the Section Molecular Plant Sciences)

Biometallic Nanoparticles: Synthesis, Functionalization and Multidisciplinary Applications

edited by

Elvira Rozhina

submission deadline 30 Nov 2026 | 2 articles | Viewed by 999 | Submission Open

Keywords: biogenic nanomaterials; antibacterial agents; plant extracts; biogenic silver nanoparticles; biofilms; cytotoxicity

(This special issue belongs to the Section Molecular Nanoscience)

New Insights into Allergic Asthma

edited by

Jose Antonio Cañas Mañas

submission deadline 30 Nov 2026 | 1 articles | Viewed by 998 | Submission Open

Keywords: allergic asthma; type 2 inflammation; airway remodeling; molecular endotypes; biomarkers; biologic therapies; immune regulation; microRNAs; extracellular vesicles; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ferroptosis: Mechanisms and Roles in Diseases

edited by Yuquan Chen

submission deadline 30 Nov 2026 | 1 articles | Viewed by 979 | Submission Open

Keywords: ferroptosis; iron metabolism; lipid peroxidation; oxidative stress; endocrine diseases; metabolic disorders; environmental exposures; circadian rhythm; redox signaling; cell death

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Oral Stem Cells: Molecular Characteristics and the Applications in Regenerative Medicine

edited by

Emi Shimizu

and

Motoki Okamoto

submission deadline 30 Nov 2026 | Viewed by 973 | Submission Open

Keywords: oral stem cells; regenerative medicine; molecular mechanisms; stem cell therapy; tissue engineering

(This special issue belongs to the Section Molecular Biology)

Spectroscopic Techniques in Molecular Sciences, 2nd Edition

edited by

Angela Staicu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 953 | Submission Open

Keywords: spectroscopy; the structure, dynamics, interactions, and functions of molecules; chemical, biological, pharmaceutical, and materials systems

(This special issue belongs to the Section Biochemistry)

Translational Insights in Solid Tumors: Bridging Molecular Mechanisms to Therapeutic Advances

edited by

Samarpan Majumder

submission deadline 30 Nov 2026 | 2 articles | Viewed by 942 | Submission Open

Keywords: solid tumors; translational research; molecular mechanisms; targeted therapy; immunotherapy; tumor microenvironment; biomarkers; drug resistance; precision oncology; clinical translation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovations in Functional Biomaterials for Biomedical Applications

edited by

Arpita Roy

submission deadline 30 Nov 2026 | 1 articles | Viewed by 941 | Submission Open

Keywords: functional biomaterials; molecular mechanisms; drug delivery systems; tissue engineering; biointerface interactions; smart/stimuli-responsive materials; molecular modeling and simulation; gene and protein expression; biomolecular characterization; regenerative medicine

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms Underlying Plant Responses to Biotic and Abiotic Stress

edited by

Mohamed Ait-El-Mokhtar

and

Raja Ben-Laouane

submission deadline 30 Nov 2026 | 1 articles | Viewed by 930 | Submission Open

Keywords: plant stress responses; abiotic stress; biotic stress; signal transduction; multi-omics; epigenetic regulation; plant–microbe interactions; biostimulants; crop resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Metabolomics in Functional Foods and Nutritional Health

edited by

Ahmed Mediani

and

Nurkhalida Kamal

submission deadline 30 Nov 2026 | 1 articles | Viewed by 916 | Submission Open

Keywords: metabolomics; functional foods; bioactive compounds; nutritional health; systems biology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Skeletal Muscle Aging: Mechanisms, Biomarkers, and Interventions

edited by

Ida Cariati

submission deadline 30 Nov 2026 | 1 articles | Viewed by 906 | Submission Open

Keywords: skeletal muscle aging; sarcopenia; muscle metabolism; mitochondrial dysfunction; inflammation; exercise adaptation; muscle adaptation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Photodiagnosis and Photodynamic Therapy

edited by

Tomasz Kubrak

and

David Aebisher

submission deadline 30 Nov 2026 | Viewed by 896 | Submission Open

Keywords: photodiagnosis; photodynamic therapy; photosensitizers; natural photosensitizers; biomedical imaging; nanomedicine; targeted therapies; light as a therapeutic tool

(This special issue belongs to the Section Molecular Pharmacology)

Interdisciplinary Molecular Design: Catalysis, Therapeutics, and Biomaterials

edited by

Zhiwei Yang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 892 | Submission Open

Keywords: intelligent molecular design; computational catalysis; antibody and protein engineering; biomaterials design; molecular dynamics simulations; AI in drug discovery

(This special issue belongs to the Section Molecular Biophysics)

Emerging Technologies in Musculoskeletal Research: From Molecular Mechanisms to Translational Innovation

edited by

Javad Tavakoli

submission deadline 30 Nov 2026 | 1 articles | Viewed by 891 | Submission Open

Keywords: musculoskeletal tissue; cell mechanobiology; biofabrication; tissue regeneration; organ-on-a-chip; disease mechanism and screening; molecular and cellular diagnostics; AI and machine learning; omics technology; wearable technologies; implant technologies; biomarkers; predictive modelling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

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