The Role of Mitochondria in Renal and Cardiac Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 15
Special Issue Editor
Special Issue Information
Dear Colleagues,
Renal and cardiac diseases represent a significant global burden, affecting one million people. These diseases converge in cardiorenal syndrome (CRS), known for inducing acute or chronic heart or kidney damage and affecting the other organ. The heart and kidneys depend on the mitochondria to produce 90% of ATP via fatty acid (FA) oxidation and oxidative phosphorylation (OXPHOS). Thus, alterations to this organelle lead to mitochondrial impairment, characterized by reduced bioenergetics, impaired biogenesis, and imbalanced dynamics. These processes cause oxidative stress, inflammation, and fibrosis, leading to organ dysfunction.
We are pleased to invite you to submit to this Special Issue focusing on the involvement of mitochondria in renal and cardiac diseases. We encourage work on the roles of mitochondrial ROS (mtROS), bioenergetics, dynamics, biogenesis, and mitochondrial metabolism.
This Special Issue will showcase the latest findings on mitochondrial dysfunction in renal or cardiac pathologies. We welcome original research articles and reviews focusing on (but not limited to) mitochondrial function, mitochondrial proteins, and mitochondrial alterations, including redox imbalance, mutations, dynamics, and bioenergetics impairment in renal and cardiac pathologies.
We look forward to receiving your contributions.
Dr. Ana Karina Aranda-Rivera
Guest Editor
Manuscript Submission Information
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Keywords
- kidney and cardiac diseases
- mitochondria
- mitochondrial impairment
- cardiorenal syndrome
- mitochondrial proteins
- dynamics
- bioenergetics
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