The Role of Mitochondria in Renal and Cardiac Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 240
Special Issue Editors
Interests: chronic kidney disease; cardiac diseases; antioxidants; mitochondria dysfunction
Interests: mitochondria; reactive oxygen species; antioxidants; renal diseases; cardiac diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Renal and cardiac diseases represent a significant global burden, affecting one million people. These diseases converge in cardiorenal syndrome (CRS), known for inducing acute or chronic heart or kidney damage and affecting the other organ. The heart and kidneys depend on the mitochondria to produce 90% of ATP via fatty acid (FA) oxidation and oxidative phosphorylation (OXPHOS). Thus, alterations to this organelle lead to mitochondrial impairment, characterized by reduced bioenergetics, impaired biogenesis, and imbalanced dynamics. These processes cause oxidative stress, inflammation, and fibrosis, leading to organ dysfunction.
We are pleased to invite you to submit to this Special Issue focusing on the involvement of mitochondria in renal and cardiac diseases. We encourage work on the roles of mitochondrial ROS (mtROS), bioenergetics, dynamics, biogenesis, and mitochondrial metabolism.
This Special Issue will showcase the latest findings on mitochondrial dysfunction in renal or cardiac pathologies. We welcome original research articles and reviews focusing on (but not limited to) mitochondrial function, mitochondrial proteins, and mitochondrial alterations, including redox imbalance, mutations, dynamics, and bioenergetics impairment in renal and cardiac pathologies.
We look forward to receiving your contributions.
Dr. Ana Karina Aranda-Rivera
Prof. Dr. José Pedraza Chaverri
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- kidney and cardiac diseases
- mitochondria
- mitochondrial impairment
- cardiorenal syndrome
- mitochondrial proteins
- dynamics
- bioenergetics
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