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Molecular Advances in Zoonoses and Vector-Borne Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 224

Special Issue Editor


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Guest Editor
Department of Internal Medicine, Mayo Clinic, Jacksonville, FL 32224-1865, USA
Interests: global health; zoonotic diseases; parasitology; vector-borne diseases; emerging viral diseases

Special Issue Information

Dear Colleagues,

Despite significant advances in public health, zoonotic and vector-borne diseases remain leading causes of human and animal morbidity. Globally, infections due to malaria, leishmaniasis, helminthic diseases, zoonotic emerging viral diseases, and gastrointestinal diseases affect hundreds of millions of people each year. Molecular approaches to these diseases—including improved techniques of epidemiology, study of immunobiology, discovery of biomarkers, surveillance of animal reservoirs, vaccine development, and drug discovery—offer hope for earlier detection, prevention, and treatment of these afflictions.

This Special Issue showcases the latest molecular advances spanning this broad group of diseases, with emphasis on applications in human and animal populations. Featured themes include drug discovery for leishmaniasis, molecular tools for monitoring soil-transmitted helminths, and paratransgenic approaches aimed at interrupting vectorial-borne transmission of human parasites.

Suitable topics include, but are not limited to, molecular tools of disease surveillance, vaccine development for parasitic diseases, drug discovery and repurposing for parasitic diseases, vector paratransgenesis, and biomarker discovery.

Dr. Ravi Durvasula
Guest Editor

Manuscript Submission Information

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Keywords

  • malaria
  • leishmaniasis
  • soil-transmitted helminths
  • one health
  • cryptosporidiosis
  • trypanosomiasis
  • mosquito-borne infections
  • arboviral diseases
  • paratransgenesis
  • drug discovery
  • biomarkers

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Published Papers (1 paper)

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Review

15 pages, 2380 KB  
Review
Therapeutic Innovations for Monkeypox Inhibition
by Nayan De, Jhuma Bhadra, Md Sorique Aziz Momin, Kamala Mitra, Debmalya Bhunia and Achinta Sannigrahi
Int. J. Mol. Sci. 2026, 27(10), 4307; https://doi.org/10.3390/ijms27104307 - 12 May 2026
Abstract
This review investigates biomaterial-based strategies for improved treatment of MPXV. We focus on emerging synthetic biomedical approaches to combating the virus. These include peptide nucleic acids, CRISPR-based systems, and small-molecule therapeutics. These methods work by targeting and blocking viral proteins and enzymes. Such [...] Read more.
This review investigates biomaterial-based strategies for improved treatment of MPXV. We focus on emerging synthetic biomedical approaches to combating the virus. These include peptide nucleic acids, CRISPR-based systems, and small-molecule therapeutics. These methods work by targeting and blocking viral proteins and enzymes. Such synthetic platforms may help reduce viral transmission and minimize side effects. They also offer potential solutions to challenges such as viral resistance in humans. In addition, biomaterials contribute to the development of more stable and effective vaccines. Combining these biomaterials with mRNA technology provides a promising framework for future vaccine development. Overall, this review underscores biomaterial-driven antiviral systems as a major frontier in translational medicine with profound implications for global health and pandemic awareness. Full article
(This article belongs to the Special Issue Molecular Advances in Zoonoses and Vector-Borne Diseases)
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