Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition

Dear Colleagues,

Epithelial-to-mesenchymal transition (EMT) is a fundamental biological process by which epithelial cells undergo several morphological modifications enabling them to acquire mesenchymal properties. This process is a complex and multifaceted process involved in both normal development and disease, including fibrosis, cancer progression and metastasis, and therapy resistance.

This Special Issue aims to provide a comprehensive overview of the molecular mechanisms and regulatory networks governing EMT. We welcome contributions focusing on signaling pathways, transcriptional and epigenetic regulation, cellular plasticity, and EMT-related biomarkers. Particularly, it is time to design properly tailored pharmacological countermeasures in order to antagonize such a process, namely by manipulating the cancer microenvironment. Therefore, studies offering novel mechanistic insights or therapeutic implications in pathological EMT contexts are particularly encouraged.

Dr. Noemi Monti
Guest Editor

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