Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 45
Special Issue Editor
Special Issue Information
Dear Colleagues,
Epithelial-to-mesenchymal transition (EMT) is a fundamental biological process by which epithelial cells undergo several morphological modifications enabling them to acquire mesenchymal properties. This process is a complex and multifaceted process involved in both normal development and disease, including fibrosis, cancer progression and metastasis, and therapy resistance.
This Special Issue aims to provide a comprehensive overview of the molecular mechanisms and regulatory networks governing EMT. We welcome contributions focusing on signaling pathways, transcriptional and epigenetic regulation, cellular plasticity, and EMT-related biomarkers. Particularly, it is time to design properly tailored pharmacological countermeasures in order to antagonize such a process, namely by manipulating the cancer microenvironment. Therefore, studies offering novel mechanistic insights or therapeutic implications in pathological EMT contexts are particularly encouraged.
Dr. Noemi Monti
Guest Editor
Manuscript Submission Information
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Keywords
- metastasis
- fibrosis
- tumor microenvironment
- molecular pathways
- EMT reversion
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