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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research in Ocular Inflammation and Infection

edited by

Christine Fardeau

submission deadline 20 May 2026 | 1 articles | Viewed by 530 | Submission Open

Keywords: ocular infections; uveitis; choroiditis; masquerade syndrome; pseudo-uveitis; intraocular lymphoma; retinal dystrophy; ocular inflammation; neuroinflammation; immunotherapy-induced uveitis; autoimmune eye diseases; sarcoidosis; OCT; indocyanine green angiography

(This special issue belongs to the Section Molecular Immunology)

Cell Death in Human Diseases: Mechanisms, Biomarkers and Therapeutic Opportunities

edited by

Decha Pinkaew

submission deadline 20 May 2026 | Viewed by 521 | Submission Open

Keywords: cell death; apoptosis; necroptosis; ferroptosis; pyroptosis; human disease; biomarkers

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Skeletal Muscle Adaptation

edited by

Michele Salanova

submission deadline 20 May 2026 | 1 articles | Viewed by 516 | Submission Open

Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes

edited by Yoram Chaiter and

Yossy Machluf

submission deadline 20 May 2026 | Viewed by 505 | Submission Open

Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Biological Breeding and Molecular Biology of Tropical Crops

edited by Yongzan Wei

submission deadline 20 May 2026 | 1 articles | Viewed by 486 | Submission Open

Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Defects of Naturally Occurring Mutations

edited by Ya-Xiong Tao

submission deadline 20 May 2026 | Viewed by 442 | Submission Open

Keywords: protein misfolding; loss of function; gain of function; pharmacological chaperone; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology

edited by Richard H. W. Funk

submission deadline 20 May 2026 | Viewed by 432 | Submission Open

Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors

(This special issue belongs to the Section Molecular Biophysics)

Antituberculous Drugs: Progress and Challenges

edited by Ana Maria Telmo Dias Pereira Vicente Cabral and

Ana Cristina Faria Ribeiro

submission deadline 20 May 2026 | Viewed by 417 | Submission Open

Keywords: antituberculostatic drugs; carriers; bioavailability; delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Cardiomyopathy: From Molecular Pathology to Treatment

edited by

Andrea Sonaglioni

and

Gian Luigi Nicolosi

submission deadline 20 May 2026 | Viewed by 393 | Submission Open

Keywords: obesity; myocardial fibrosis; subclinical myocardial dysfunction; fibrotic remodeling; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathogenesis and Treatment of Prostate Cancer

edited by

Vincenzo Fiorentino

submission deadline 20 May 2026 | Viewed by 370 | Submission Open

Keywords: prostate cancer; pathogenesis; genetic mutations; target therapy; surgery; radiation therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Neurofibromatosis Type 1: From Molecular Insights to Novel Therapies

edited by László Szabó and

Márta Medvecz

submission deadline 20 May 2026 | Viewed by 353 | Submission Open

Keywords: neurofibromatosis type 1; genotype– phenotype analyses; molecular pathogenesis; next-generation sequencing (NGS); molecular targeted therapy; MEK inhibitors; imaging studies

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Understanding Respiratory Virus–Host Interactions

edited by Kun Li

submission deadline 20 May 2026 | Viewed by 350 | Submission Open

Keywords: respiratory viruses; virus– host interactions; molecular mechanisms; viral replication; host– immune response; molecular pathogenesis; molecular signaling; antiviral strategies

(This special issue belongs to the Section Molecular Microbiology)

Advanced Research in Nanophotonics and Biophotonics

edited by

Prabhakar Pradhan

submission deadline 20 May 2026 | Viewed by 342 | Submission Open

Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics

(This special issue belongs to the Section Molecular Nanoscience)

New Advances in Reproductive Immunology and Pathology

edited by Silvia Giugliano

submission deadline 20 May 2026 | Viewed by 328 | Submission Open

Keywords: maternal– fetal immune tolerance; reproductive immunopathology; cytokine signaling in pregnancy; immune-related infertility; metabolome-immune crosstalk; microbiome influence on fertility

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Antimicrobial Agents: Mechanisms and Applications

edited by

Aleksandra Maria Kocot

submission deadline 20 May 2026 | Viewed by 322 | Submission Open

Keywords: antimicrobial compounds; antibacterial activity; antibiotic resistance; pathogen-tailored therapeutic targeting; novel antimicrobials; molecular aspects of the mechanisms of action of antibacterial substances; effectiveness of antibacterial substances

(This special issue belongs to the Section Biochemistry)

Microbiome in Cancer: From Pathogenesis to Therapeutic Innovation

edited by

Francesca Benedetti

and

Davide Zella

submission deadline 20 May 2026 | Viewed by 317 | Submission Open

Keywords: microbiome; cancer; anticancer drugs; chemoresistance; immune modulation

(This special issue belongs to the Section Molecular Microbiology)

Advanced Research on Comparative Reproductive Physiology

edited by

Heriberto Rodriguez-Martinez

and

Manuel Álvarez-Rodríguez

submission deadline 20 May 2026 | Viewed by 317 | Submission Open

Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species

(This special issue belongs to the Section Molecular Biology)

Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine

edited by

Mariapaola Marino

submission deadline 20 May 2026 | Viewed by 281 | Submission Open

Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms Linked to Exercise

edited by Igor Zubrzycki

submission deadline 20 May 2026 | Viewed by 272 | Submission Open

Keywords: molecular mechanisms; exercise adaptations; translational health

(This special issue belongs to the Section Molecular Biology)

Targeted Protein Degradation: From Molecular Mechanisms to Therapeutic Applications

edited by

Asim Debnath

submission deadline 20 May 2026 | Viewed by 268 | Submission Open

Keywords: targeted protein degradation; ubiquitin– proteasome system; PROTAC; drug design; medicinal chemistry

(This special issue belongs to the Section Molecular Pharmacology)

Latest Molecular Advances in Prostate Cancer

edited by Rejane Maira Góes

submission deadline 20 May 2026 | Viewed by 267 | Submission Open

Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Application of Hyaluronan in Tissue Healing

edited by

Antonella D'Agostino

submission deadline 20 May 2026 | Viewed by 252 | Submission Open

Keywords: wound healing; inflammation; remodeling; chronic wound; wound dressing; scar tissue; sound tissue; biomarkers; chemical modification; crosslinked; biopolymer; biological activity

(This special issue belongs to the Section Macromolecules)

Gut–Brain Axis: Pathophysiological Mechanisms in Neurological Disorders and Metabolic Diseases

edited by

Giovanna Traina

submission deadline 20 May 2026 | Viewed by 245 | Submission Open

Keywords: gut– brain axis; intestinal microbiota; mood diseases; immune system; microbial molecules; behavior; metabolic diseases; signaling pathways; inflammation; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Blood–Brain Barrier Dysfunction in Neurodegenerative Disorders

edited by

Amal Kaddoumi

submission deadline 20 May 2026 | Viewed by 245 | Submission Open

Keywords: blood– brain barrier; neurodegenerative diseases; Alzheimer’ s disease; amyotrophic lateral sclerosis; Parkinson's disease; BBB as a therapeutic target; neuroinflammation; molecular mechanisms; cerebral blood flow

(This special issue belongs to the Section Molecular Neurobiology)

AI and Machine Learning in Molecular Biomarker Discovery and Mechanisms of Neurodegenerative Disorders

edited by

Seyed Ehsan Saffari

submission deadline 20 May 2026 | Viewed by 242 | Submission Open

Keywords: artificial intelligence (AI); machine learning (ML); biomarker discovery; neurodegenerative disorders; Alzheimer’ s disease (AD); Parkinson’ s disease (PD); dementia; risk prediction models; multi-omics integration; translational bioinformatics

(This special issue belongs to the Section Molecular Neurobiology)

mRNA/miRNAs Network in Diabetes and Its Complications

edited by

Daniela Lixandru

submission deadline 20 May 2026 | Viewed by 231 | Submission Open

Keywords: RNA/miRNAs; exosomes; regenerative medicine; translational medicine; adipose tissue biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biological Effects of Radiation on Human Cells and Tissues

edited by

Maria Paola Bertuccio

submission deadline 20 May 2026 | Viewed by 227 | Submission Open

Keywords: radiation exposure; molecular pathways; inflammation; immune response; biochemical markers; electromagnetic hypersensitivity

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Environmental Stress-Induced Human Diseases

edited by

Silvia Cantara

submission deadline 20 May 2026 | Viewed by 223 | Submission Open

Keywords: environmental stress; oxidative stress; inflammation; epigenetic modifications; DNA damage and repair; cellular signaling pathways; mitochondrial dysfunction; autophagy; air pollution; heavy metal toxicity; endocrine disruptors; climate change and health; neurodegeneration; cancer biology; immune system dysregulation; gene– environment interactions; biomarkers of exposure and disease; systems biology; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stress-Activated Molecular Remodeling: Lipids, Chaperones, and the Cytoskeleton

edited by

Nikolas Nikolaidis

submission deadline 20 May 2026 | Viewed by 221 | Submission Open

Keywords: cellular stress response; molecular remodeling; lipid signaling; membrane dynamics; cytoskeletal reorganization; chaperones; heat shock proteins; proteostasis; membrane– protein interactions; stress-induced trafficking; mechano-transduction; cell survival signaling

(This special issue belongs to the Section Molecular Biology)

ErbB Family of Receptor Tyrosine Kinases in Cancer and Drug Therapy

edited by Ilaria Marrocco and

Donatella Romaniello

submission deadline 20 May 2026 | Viewed by 218 | Submission Open

Keywords: ErbB; RTKs; EGFR; HER2; HER3; cancer; targeted therapies; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 20 May 2026 | Viewed by 217 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

The Gene, Genomics, and Molecular Breeding in Cruciferae Plants (3rd Edition)

edited by

Maoteng Li

submission deadline 20 May 2026 | Viewed by 212 | Submission Open

Keywords: Cruciferae plants; genome analysis; genetic dissection; gene function; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Male Infertility and Fertility

edited by

Mariaimmacolata Preianò

submission deadline 20 May 2026 | Viewed by 210 | Submission Open

Keywords: male infertility; infertility treatment; omics approaches; proteomics; metabolomics; lipidomics; mass spectrometry; signaling pathways; biomarker discovery; reproductive medicine; precision medicine; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Perineuronal Nets and Fear Memories Erasure: State of the Art and Future Directions

edited by

Andrea Poli

submission deadline 20 May 2026 | Viewed by 209 | Submission Open

Keywords: perineuronal nets (PNNs); extracellular matrix (ECM); fear erasure; traumatic memories; PTSD; translation research; clinical treatment; therapeutical strategies

(This special issue belongs to the Section Molecular Neurobiology)

Omics Approaches to Unravel Plant Responses to Habitat Stresses

edited by

Claudia Uhde-Stone

submission deadline 20 May 2026 | Viewed by 202 | Submission Open

Keywords: omics; multi-omics; high-throughput technologies; biotic stress; abiotic stress; environmental stress; crosstalk; translational biology; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Autophagy and Apoptosis in Mammal Cells

edited by Kaja Urbańska and Anna Litwiniuk

submission deadline 20 May 2026 | Viewed by 198 | Submission Open

Keywords: autophagy; apoptosis; cellular homeostasis; intra- and intercellular crosstalk; autophagic cell death; programmed cell death

(This special issue belongs to the Section Molecular Biology)

Neuropeptides in Brain Health and Disease: From Molecular Mechanisms to Therapeutic Potential

edited by

Alessandro Castorina

submission deadline 20 May 2026 | 1 articles | Viewed by 196 | Submission Open

Keywords: neuropeptides; brain function; neuroinflammation; regeneration; neurodegeneration; biomarkers; therapy; CNS; brain disorders; demyelination

(This special issue belongs to the Section Molecular Neurobiology)

Natural Product as Therapeutic Agent: From Molecular Targets to Cellular and Functional Modulation

edited by Su-Yun Lyu

submission deadline 20 May 2026 | Viewed by 194 | Submission Open

Keywords: natural products; molecular targets; cellular modulation; functional modulation; therapeutic agents

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Perspectives in Tissue Engineering and Regenerative Medicine

edited by

Sorina Dinescu

submission deadline 20 May 2026 | Viewed by 193 | Submission Open

Keywords: 3D scaffolds; personalized regenerative therapies; tissue engineering; stem cells; bone regeneration; regenerative biomarkers; cell– scaffold interactions; nanomaterials

(This special issue belongs to the Section Molecular Biology)

Effects of the Environmental Conditions on Bacterial Growth and Functions

edited by

Fernanda Abreu

submission deadline 20 May 2026 | Viewed by 189 | Submission Open

Keywords: bacterial growth; growth conditions; gene expression; bioproducts; biofilm; resistance; population dynamics

(This special issue belongs to the Section Molecular Microbiology)

The Role of miRNAs in Healthy Lungs and Chronic Lung Diseases

edited by Victor Ruiz

submission deadline 20 May 2026 | Viewed by 185 | Submission Open

Keywords: miRNA; DROSHA; DICER; DGCR8; ADAR; pulmonary fibrosis; COPD; asthma; lung neoplasm

(This special issue belongs to the Section Molecular Biology)

Recent Progress in Nanomedicine for Cancer Therapy

edited by Peisheng Xu

submission deadline 20 May 2026 | Viewed by 185 | Submission Open

Keywords: nanomedicine; cancer-targeted therapy; theragnostic; nanodevice

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification

edited by

Ágnes Szepesi

submission deadline 20 May 2026 | Viewed by 182 | Submission Open

Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano– bio interactions; crop production; plant-based solutions; bio-corona

(This special issue belongs to the Section Molecular Plant Sciences)

Current and Emerging Therapeutic Approaches for MASLD

edited by

Chrysoula Boutari

submission deadline 20 May 2026 | Viewed by 180 | Submission Open

Keywords: MASLD; MASH; GLP-1 agonists; anti-inflammatory agents; anti-obesity drugs; FGF-21

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genomic and Molecular Insights into Emerging and Reemerging Pathogens

edited by

Fabio Scarpa

submission deadline 20 May 2026 | Viewed by 179 | Submission Open

Keywords: pathogens genomic analysis; evolution transmission dynamics; pathogenic mechanisms; viruses; bacteria; fungi; parasites; next-generation sequencing; metagenomics; bioinformatics; genetic variations; adaptive mutations; host– pathogen interactions; emerging pathogens; molecular epidemiology; host immune responses; pathogen genetics

(This special issue belongs to the Section Molecular Immunology)

Latest Research in Neuroinflammation

edited by Reza Khorooshi

submission deadline 20 May 2026 | Viewed by 178 | Submission Open

Keywords: neuroinflammation; central nervous system disorders; neuroimmune interactions; inflammation and neurodegeneration; therapeutic strategies in neurology

(This special issue belongs to the Section Molecular Neurobiology)

Drug and Non-Drug Treatment of Cerebral Diseases

edited by

Silvia Carloni

submission deadline 20 May 2026 | Viewed by 176 | Submission Open

Keywords: cerebral diseases; cerebral ischemia; neonatal hypoxic-ischemic encephalopathy (HIE); neuroprotection; therapeutic hypothermia; neurorehabilitation; oxidative stress; stem cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Peptides: Function, Metabolism and Synthesis

edited by

Leandro Mantovani de Castro

submission deadline 20 May 2026 | Viewed by 175 | Submission Open

Keywords: bioactive peptides; antimicrobial peptides; antitumoral peptides; neurodegenerative diseases; metabolic diseases; chemical synthesis; cellular proteolysis; mass spectrometry; peptidomics; intracellular peptides; micropeptides

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Quantum Chemical Intelligence: New Horizons of Molecular Structure and Reactivity

edited by

Mihai V. Putz

submission deadline 20 May 2026 | Viewed by 173 | Submission Open

Keywords: chemical bond and bonding; quantum states and measurements; chemical reactivity; valence models; complex coordination; reaction coordinates and paths; bio-nano-materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Vector–Pathogen–Host Interaction, Vaccines and Immunobiologicals

edited by Carlo José Freire Oliveira and

Marcos Vinícius Da Silva

submission deadline 20 May 2026 | Viewed by 167 | Submission Open

Keywords: host– pathogen– vector interactions; active biomolecules; immunomodulation; vaccines; binding molecules; immunobiologicals

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 3001-3050 on page 61 of 66.

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