Biological Effects of Radiation on Human Cells and Tissues
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 May 2026 | Viewed by 1534
Special Issue Editor
Interests: biomarkers; clinical biochemistry; oxidative stress; inflammation; cell cultures; gene expression analyses
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Radiation exposure leads to multifaceted cell and tissue alterations, some of which are harmful while others are beneficial, depending on the radiation investigated. Regarding the harmful effects, these could be mediated by direct DNA damage and the generation of ROS. Exposure to radiation triggers a cascade of molecular events, which can lead to inflammation and necrosis, as well as chronic complications such as fibrosis and organ dysfunction. The radiation dose, duration of exposure, and the subject's radiosensitivity all influence the severity of damage.
On the other hand, low-energy radiation can be used as a therapeutic tool to enhance a variety of cellular processes with beneficial physiological effects, including modulation of immune responses, resolution of inflammation, mitochondria activation, and tissue regeneration.
The purpose of this Special Issue is to provide a comprehensive overview and new insights into recent advances in the above research areas, clarifying which molecular mechanisms are involved in the response to radiation exposure.
Original research articles and reviews (systematic reviews, narrative reviews, and meta-analyses) are welcomed.
Dr. Maria Paola Bertuccio
Guest Editor
Manuscript Submission Information
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Keywords
- radiation exposure
- molecular pathways
- inflammation
- immune response
- biochemical markers
- electromagnetic hypersensitivity
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