Microbiome in Cancer: From Pathogenesis to Therapeutic Innovation

Dear Colleagues,

Recent studies highlight the critical role of the microbiome in modulating the efficacy and resistance of anticancer therapies. As cancer remains a significant global health burden, understanding the molecular interactions between the microbiome and anticancer drugs could unveil novel strategies to overcome drug resistance. This Special Issue titled “Molecular Studies on the Impact of Microbiome on Anticancer Drug Resistance” aims to gather original research and comprehensive reviews that delve into these complex interactions. We invite contributions that explore how microbiome composition, metabolic pathways, and microbial-derived molecules affect cancer cell responses to therapies. Topics of interest include, but are not limited to, the role of microbial metabolites, immune modulation by microbiota, microbiome-influenced drug metabolism, and the identification of microbiome-based biomarkers for therapy resistance.

This issue also welcomes studies examining how targeted manipulation of the microbiome composition and its metabolites might improve therapeutic outcomes or reduce side effects. By compiling cutting-edge research, we hope this Special Issue will deepen the understanding of microbiome influences on drug resistance and inspire novel approaches to enhance cancer treatment efficacy.

Dr. Francesca Benedetti
Dr. Davide Zella
Guest Editors

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