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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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25th Anniversary of IJMS: Updates and Advances in "Materials Science" Section

edited by

Miklós Fried

and

Filippo Rossi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2091 | Submission Open

Keywords: nanomaterials; functional polymers; bio-inspired systems; complex intelligent; responsive materials

(This special issue belongs to the Section Materials Science)

25th Anniversary of IJMS: Updates and Advances in Molecular Informatics

edited by

M. Natália D.S. Cordeiro

and

Giulio Vistoli

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1998 | Submission Open

Keywords: AI-guided drug repurposing; virtual screening in personalized medicine; machine learning for toxicity prediction; network-based biomarkers in complex diseases; in silico pharmacokinetics and ADMET profiling; data-driven materials design; deep learning for molecular property prediction; AI-assisted nanomaterial synthesis; systems biology models for metabolic engineering

(This special issue belongs to the Section Molecular Informatics)

Physicochemical Properties and Applications of Nanomaterials in Biology and Medicine

edited by

Gangho Lee

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1947 | Submission Open

Keywords: nanoparticle; nanomaterial; biomedicine; synthesis; physicochemical properties; imaging; therapy; contrast agent; therapeutic agent

(This special issue belongs to the Section Molecular Nanoscience)

Biomolecular Structure, Function and Interactions: 2nd Edition

edited by

Ivo Crnolatac

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1915 | Submission Open

Keywords: biophysical chemistry; protein– protein interactions; protein– DNA interactions; protein– ligand interactions; receptor– ligand interactions; biomolecular structure and function; protein folding and stability

(This special issue belongs to the Section Biochemistry)

Research Progress in Cellular Senescence in Health and Disease

edited by

Gabriella Teti

and Mirella Falconi

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1885 | Submission Open

Keywords: senotherapy; cellular senescence; physiological relations; pathological relations; cell biology in aging; age-related diseases; senescence in mesenchymal stroma cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Technologies and Molecular Approaches in Brain Disease Diagnosis and Therapy

edited by

Furong Tian

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1867 | Submission Open

Keywords: neurodegenerative diseases; brain cancer; nanotechnology

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research and Advances in Ocular Disease

edited by Da-Wen Lu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1863 | Submission Open

Keywords: ophthalmology; AI; ocular; eye diseases; retina; cornea; glaucoma; neuro-ophthalmology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Genome Evolution and Environmental Adaptation

edited by

Zhonghu Li

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1773 | Submission Open

Keywords: plant phylogeny; genome evolution; molecular evolution of cytoplasmic genomes; species divergence

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into RNA Diseases

edited by

Naoyuki Kataoka

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1710 | Submission Open

Keywords: RNA splicing; RNA modification; RNA processing; translation; RNA transport

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Ovarian Cancer Metastasis and Chemotherapy Resistance

edited by

Carmela Ricciardelli

and

Noor A. Lokman

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1589 | Submission Open

Keywords: ovarian cancer; metastasis; biomarkers; chemotherapy resistance; tumor microenvironment; peritoneal– cancer cell interactions; proteomics; novel therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Advances in Conventional Tree Breeding: Integrating Phenotypic Selection, Genetic Gain, and Sustainable Forest Management

edited by

Jingli Yang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1539 | Submission Open

Keywords: forest trees; genetic breeding; conventional tree breeding; forest management; forest tree varieties; modern molecular technology; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Nanobiomaterials and Beyond: Innovations in Drug Delivery, Diagnostics, and Therapeutics

edited by

Alexandru Mihai Grumezescu

and

Adelina-Gabriela Niculescu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1458 | Submission Open

Keywords: nanobiomaterials; drug delivery systems; targeted drug delivery; controlled drug release; stimulus-responsive nanomaterials; biocompatibility; biodegradability; functionalized nanocarriers; theranostics; nanocarriers for cancer therapy; tumor-targeted drug delivery; organ-specific delivery systems; pH-responsive materials; temperature-sensitive nanobiomaterials; light-activated drug delivery; enzyme-responsive systems; multimodal nanomaterials; translational nanomedicine; computational modeling in nanobiomaterials; preclinical studies of nanomaterials

(This special issue belongs to the Section Materials Science)

Highlights in Pathophysiology and Treatment of Osteoarthritis

edited by

Antonella Fioravanti

and

Serena Guiducci

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1449 | Submission Open

Keywords: osteoarthritis; pathophysiology (cytokines; adipokines; chemokines; epigenetics; microbiome); cartilage; synovial membrane; subchondral bone; treatment; disease-modifying osteoarthritis drugs; non-pharmacological treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Melanoma: From Molecular Pathology to Therapeutic Approaches, 2nd Edition

edited by

Michael Eccles

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1434 | Submission Open

Keywords: melanoma; pathology; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Focus on Plant Biotechnology and Molecular Breeding

edited by

Magdalena Wróbel-Kwiatkowska

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1431 | Submission Open

Keywords: genetic engineering; plant transformation; applied biotechnology; functional genomics; crop plants; crop improvement; plant tissue cultures; secondary metabolites

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Research of Plant-Pathogen Interaction

edited by

Hyong Woo Choi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1380 | Submission Open

Keywords: molecular plant-pathogen interactions; pathogen detection; secondary metabolism; multi-omics approaches; antibiotic resistance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology of Human Reproduction

edited by

Houda Amor

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1176 | Submission Open

Keywords: human reproduction; genomics; transcriptomics; proteomics; imaging technologies

(This special issue belongs to the Section Molecular Biology)

Advances in Forensic Molecular Biology and Genetics

edited by

Anna Barbaro

submission deadline 31 Dec 2025 | Viewed by 1150 | Submission Open

Keywords: nuclear and mt-DNA; rapid DNA analysis; next-generation sequencing; mRNA analysis; microbiome analysis; barcode DNA; time since deposition; fluid identification; DNA phenotyping; DNA ancestry

(This special issue belongs to the Section Molecular Biology)

Food Allergy: Molecular Mechanisms, Clinical Challenges, and Future Directions

edited by

Sylwia Smolińska

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1149 | Submission Open

Keywords: food allergy; allergen; environmental exposures; gut microbiome; non-IgE-mediated pathways

(This special issue belongs to the Section Molecular Immunology)

Nature-Inspired and Synthetic Compounds: New Frontiers in Bioactivity and Drug Discovery

edited by

Alina Bora

and

Luminita Crisan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1139 | Submission Open

Keywords: natural and synthetic products; drug discovery and development; drug repurposing; artificial intelligence and machine learning; biological evaluation; healthcare; green and sustainable chemistry; natural and synthetic drug applications

(This special issue belongs to the Section Bioactives and Nutraceuticals)

25th Anniversary of IJMS: Updates and Advances in Molecular Pharmacology

edited by

Roberto Scatena

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1062 | Submission Open

Keywords: precision medicine; pharmacogenomics; targeted protein degradation (TPD); molecular pharmacology; RNA Therapeutics; novel drug modalities; proteomics; transcriptomics; personalized drug therapy

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Inflammasomes

edited by

Roberto Negro

submission deadline 31 Dec 2025 | Viewed by 1051 | Submission Open

Keywords: inflammasome; pyroptosis; innate immunity; cancer; neurodegenerative diseases; microbiota; gasdermin; ninjurin; drug screening; personalized treatments; multi-omics analysis

(This special issue belongs to the Section Molecular Immunology)

Upcycling Food Industry By-Products: Bioactive Ingredients for Nutrition and Health

edited by

Giusy Rita Caponio

and

Graziana Difonzo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 959 | Submission Open

Keywords: bioactive compounds; food by-products; functional foods; molecular mechanisms; polyphenols; oxidative stress; inflammation; nutrigenomics; microbiome; prebiotics; postbiotics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Trends in Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics: 3rd Edition

edited by

Ramón Cacabelos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 906 | Submission Open

Keywords: Alzheimer’ s disease; pathogenic mechanisms; genomics; epigenetics; biomarkers; prevention; treatment; pharmacogenetics

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Breeding for Important Economic Traits in Livestock

edited by

Dawei Wei

and

Syed Haidar Abbas Raza

submission deadline 31 Dec 2025 | Viewed by 880 | Submission Open

Keywords: molecular breeding; livestock genetics; economic traits; genomic selection; adipogenesis; feed efficiency; disease resistance; non-coding RNAs; multi-omics; genetic improvement

(This special issue belongs to the Section Molecular Biology)

Atherosclerosis and Comorbidities: From Molecular Pathogenesis to Diagnosis and Therapeutic Targets

edited by

Alexandr Ceasovschih

Victoriţa Şorodoc

and

Yusuf Ziya Şener

submission deadline 31 Dec 2025 | Viewed by 835 | Submission Open

Keywords: atherosclerosis; comorbidities; lipidology; inflammation; obesity; arterial stiffness; vascular remodeling; cardiovascular risk; cardiovascular diseases; targeted therapies; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Trends in Enzymology

edited by

Francesco Malatesta

submission deadline 31 Dec 2025 | Viewed by 806 | Submission Open

(This special issue belongs to the Section Biochemistry)

Enzymes and Enzyme Inhibitors—Applications in Medicine and Diagnosis, 3rd Edition

edited by

Athina Geronikaki

submission deadline 31 Dec 2025 | 1 articles | Viewed by 777 | Submission Open

Keywords: enzyme; enzyme inhibitor; drug target; enzyme deficiency; enzyme overexpression; biomarker; drugs; diagnosis; therapy

(This special issue belongs to the Section Molecular Pharmacology)

Advances in the Synthesis and Study of Novel Bioactive Molecules

edited by

Adriana Georgieva Bakalova

and

Emiliya Demireva Cherneva

submission deadline 31 Dec 2025 | 1 articles | Viewed by 696 | Submission Open

Keywords: organic compounds; metal complexes; bioactive molecules

(This special issue belongs to the Section Biochemistry)

Red Blood Cells: Dynamic Regulators, Disease Indicators and Therapeutic Targets

edited by Leonid Livshits

submission deadline 31 Dec 2025 | 1 articles | Viewed by 673 | Submission Open

Keywords: red blood cell (RBC); RBC biochemical; hemodynamic; biophysical properties

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Plasma in Seed and Plant Treatment

edited by

Ricardo Molina

and

Karina Balestrasse

submission deadline 31 Dec 2025 | Viewed by 670 | Submission Open

Keywords: seed; plant; plasma; germination; dormancy; sterilization; reactive oxygen species; reactive nitrogen species; molecular mechanism; growth promotion; essential oils; plant stem cells; seed coating and pelleting

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in Molecular Research and Therapeutic Strategies for Endometrial Cancer

edited by

Yung-Taek Ouh

submission deadline 31 Dec 2025 | 1 articles | Viewed by 669 | Submission Open

Keywords: endometrial cancer; molecular classification; biomarkers; precision medicine; targeted therapy; immunotherapy; early detection; non-invasive diagnostics; genomic profiling; translational research

(This special issue belongs to the Section Molecular Oncology)

Microbial Fermentation: Advances in Synthetic Biology, Metabolic Engineering, and Biomanufacturing

edited by

Yaokang Wu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 667 | Submission Open

Keywords: microbial fermentation; synthetic biology; metabolic engineering; biomanufacturing; industrial biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Chelating Ligands in Therapeutics: Recent Advances and Future Directions

edited by

Matteo Mori

and

Fiorella Meneghetti

submission deadline 31 Dec 2025 | Viewed by 634 | Submission Open

Keywords: metal complexes; chelation therapy; chelating agents; diagnostic imaging; metal detoxification; chelation pharmacokinetics

(This special issue belongs to the Section Biochemistry)

Advancing Research on Alexander Disease

edited by

Ming-Der Perng

submission deadline 31 Dec 2025 | Viewed by 611 | Submission Open

Keywords: Alexander disease; astrocyte dysfunction; intermediate filaments; GFAP; astrogliosis; neurodegeneration; leukodystrophy; rare disease; rosenthal fibers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant RNA Biology: Non Coding RNAs in Plant Development, Defense, and Adaptation

edited by

Andrew Eamens

submission deadline 31 Dec 2025 | 1 articles | Viewed by 608 | Submission Open

Keywords: plant RNA biology; regulatory RNA; non-coding RNA; small RNA (including miRNAs and siRNAs); RNA interacting proteins; plant development; plant pathogen defense; plant environmental stress adaptation

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Therapeutic Strategies for Pregnancy Complications

edited by

Joško Osredkar

submission deadline 31 Dec 2025 | 1 articles | Viewed by 604 | Submission Open

Keywords: pregnancy complications; placenta diseases; molecular mechanisms; therapeutics; biomarkers; preeclampsia; gestational diabetes; intrauterine growth restriction; maternal-fetal exchange; inflammation mediators

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Carbon Fiber, Carbon Nanofiber for Composites: Synthesis, Processing, Molecular Structure, Characterization, and Application

edited by Tridung Ngo

submission deadline 31 Dec 2025 | Viewed by 588 | Submission Open

Keywords: carbon fiber; carbon nanofiber; nanotube; carbon fiber composites; synthesis; advanced manufacturing; characterization; recent advancements; applications

(This special issue belongs to the Section Materials Science)

T-Cell Lymphoma: From Basic Science to Novel Therapeutics

edited by

Daniele Caracciolo

and

Andrea Duminuco

submission deadline 31 Dec 2025 | Viewed by 571 | Submission Open

Keywords: T-cell lymphoma; targeted therapy; immunotherapy; translational research; real-world experience

(This special issue belongs to the Section Molecular Oncology)

Bacterial Infections: Unraveling Pathogenesis, Resistance, and Therapeutic Frontiers

edited by

Jagoda Jablonska

submission deadline 31 Dec 2025 | 1 articles | Viewed by 569 | Submission Open

Keywords: antimicrobial resistance; host– pathogen interactions; bacterial molecular pathogenesis; therapeutic target discovery

(This special issue belongs to the Section Molecular Microbiology)

Emerging Trends of Quantum Mechanics, Computational Chemistry, and Spectroscopy in Physical Chemistry

edited by

Dongho Kim

submission deadline 31 Dec 2025 | Viewed by 566 | Submission Open

Keywords: quantum theory; computational chemistry; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Supramolecular Liquid Crystal Compounds—from Molecular Design to Functional Materials

edited by

Katarzyna Merkel

submission deadline 31 Dec 2025 | Viewed by 563 | Submission Open

Keywords: supramolecular; self-assembled; liquid crystal; hydrogen bonding

(This special issue belongs to the Section Materials Science)

Molecular Dynamics Techniques in the Artificial Intelligence Era

edited by

Luciano Tavares Costa

Andrew S. Paluch

and Itamar Borges Junior

submission deadline 31 Dec 2025 | Viewed by 560 | Submission Open

Keywords: molecular dynamics; machine learning; force field; free energy; statistical mechanics; algorithm development; artificial intelligence

(This special issue belongs to the Section Molecular Informatics)

Molecular Entomology of Insects of Economic Importance: Advanced Molecular Approaches for Insect Pest Management

edited by

T. G. Emyr Davies

submission deadline 31 Dec 2025 | Viewed by 525 | Submission Open

Keywords: molecular entomology; insect pests; agricultural pests; disease vectors; beneficial insects; CRISPR; RNA interference; genome-wide approaches; computational biology; nanotechnology

(This special issue belongs to the Section Molecular Biology)

Targeted Pharmacological Modulation of Cellular Pathology and Drug Discovery: A Translational Approach to Bridge Laboratory Discoveries with Clinical Practice

edited by Saurav Mallik

submission deadline 31 Dec 2025 | 1 articles | Viewed by 512 | Submission Open

Keywords: targeted pharmacotherapy; cellular pathology; translational medicine; drug mechanism of action; signal transduction modulation; precision medicine; apoptosis and autophagy; biomarker-guided therapy; pathophysiology-driven drug design; clinical applications of molecular targets; molecular docking

(This special issue belongs to the Section Molecular Pharmacology)

Design of Polymer Composites for Biomedical Applications

edited by

Valentina Vassallo

submission deadline 31 Dec 2025 | Viewed by 507 | Submission Open

Keywords: biocompatibility; polymers; biomaterials; tissue regeneration; mesenchymal cells; wound healing

(This special issue belongs to the Section Materials Science)

Role of Mesenchymal Stem/Stromal Cells (MSCs) in Human Diseases and Their Treatment

edited by

Mirjana Jerkic

submission deadline 31 Dec 2025 | Viewed by 506 | Submission Open

Keywords: mesenchymal stem/stromal cells (MSCs); MSC homing; MSC properties; immune cells; macrophages; injury; inflammation; cell therapy

(This special issue belongs to the Section Molecular Immunology)

State-of-the-Art Electrochemical Reaction Technologies

edited by

Cornelia Bandas

and

Carmen Lǎzǎu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 481 | Submission Open

Keywords: energy storage; electrochemical sensors; electrocatalysis; supercapacitors; molecular electrochemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Current Progress in Neutrophil Extracellular Traps (NETs)

edited by

Joanna Czerwińska

submission deadline 31 Dec 2025 | Viewed by 471 | Submission Open

Keywords: PAD4; NETs; autoimmune diseases; CECNs; autoantibodies

(This special issue belongs to the Section Molecular Immunology)

Molecular Research on the Pathology and Treatment of Sepsis and Non-Infectious Inflammatory Conditions

edited by

Andressa Freitas

submission deadline 31 Dec 2025 | 1 articles | Viewed by 415 | Submission Open

Keywords: sepsis; comorbidities; inflammation; molecular mechanisms; cytokine signaling; oxidative stress; leukocyte recruitment; therapeutic targets

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 651-700 on page 14 of 65.

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