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Design of Polymer Composites for Biomedical Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: closed (31 December 2025) | Viewed by 969

Special Issue Editor


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Guest Editor
1. Department of Experimental Medicine, School of Medicine, University of Campania Luigi Vanvitelli, 80035 Naples, Italy
2. Department of Life Sciences, Health and Health Professions, Link Campus University, 00165 Rome, Italy
Interests: biocompatibility; biomaterials; cells proliferation assay; wound healing assay
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Special Issue Information

Dear Colleagues,

Nowadays, the demand for innovative scaffolds/biomaterials/gels based on biocompatible polymers is increasingly widespread.

In fact, the relative applications are countless, from wound healing, to anti-inflammatory activity, to the intriguing tissue regeneration.

The aim of this special issue is to share with the scientific community novel biocompatible polymer composites with potential application at the cellular and/or biochemical level.

Original research articles and mini- and complete reviews are welcome.

Potential topics include, but are not limited to, the following:

  • The design and preparation of scaffolds/gels/hydrogel based on modified or unmodified polymers;
  • The development of Biocompatible Polymer Composites with application in wound healing;
  • Biocompatible Polymer Composites with potential anti-oxidant and anti-inflammatory effects;
  • New strategies for producing polymers composite with the aim to implant mesenchymal cells and application in regenerative medicine.

Dr. Valentina Vassallo
Guest Editor

Manuscript Submission Information

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Keywords

  • biocompatibility
  • polymers
  • biomaterials
  • tissue regeneration
  • mesenchymal cells
  • wound healing

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Published Papers (1 paper)

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Research

15 pages, 4122 KB  
Article
Sol-Gel Synthesis of New Bioactive Organic-Inorganic Materials for Biomedical Use: SiO2/Ferulic Acid/PEG
by Federico Barrino, Federica Giuliano, Harrison de la Rosa-Ramírez and María Dolores Samper
Int. J. Mol. Sci. 2026, 27(6), 2698; https://doi.org/10.3390/ijms27062698 - 16 Mar 2026
Viewed by 349
Abstract
In this study, a series of SiO2-based biomaterials synthesized via the sol-gel technique was developed by integrating different weight percentages (10wt% and 15wt%) of ferulic acid (FA) and varying weight percentages (6wt%, 12wt%, [...] Read more.
In this study, a series of SiO2-based biomaterials synthesized via the sol-gel technique was developed by integrating different weight percentages (10wt% and 15wt%) of ferulic acid (FA) and varying weight percentages (6wt%, 12wt%, and 24wt%) of polyethylene glycol (PEG). Chemical characterization of the materials was performed by FTIR-ATR spectroscopy to confirm the incorporation of the functional agents and the matrix structure. Biocompatibility was assessed through cell-based assays and gene expression analysis, highlighting a positive effect of the materials on cell proliferation and the regulation of key markers for tissue regeneration. Finally, the ability to induce hydroxyapatite (HA) formation was verified using simulated body fluid (SBF) following the Kokubo test, demonstrating the bioactive potential of the treated surfaces. The obtained results indicate that the combination of SiO2, FA, and PEG via sol-gel represents a promising platform for applications in the field of bone regeneration and functional biomaterials. Full article
(This article belongs to the Special Issue Design of Polymer Composites for Biomedical Applications)
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