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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Jan 2026 | Viewed by 132 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Clinical Biochemistry, 2nd Edition

edited by Yu Chen

submission deadline 31 Jan 2026 | Viewed by 132 | Submission Open

Keywords: clinical biochemistry; medical diagnosis; biomarkers; proteomic profiling; metabolomic profiling; high throughput technologies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Endoscopy and Diagnostic Tools in Hepatobiliary and Pancreatic Diseases, Second Edition

edited by

Stefano Francesco Crinò

submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open

Keywords: endoscopic ultrasound; eRCP; radiomics; tissue acquisition; artificial intelligence; magnetic resonance imaging; cholangioscopy; pancreatic cancer; pancreatic cysts; hepatocellular carcinoma; cholangiocarcinoma

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Tipping Point: Advances in the Diagnosis and Management of Acute-on-Chronic Liver Failure and End-Stage Liver Disease

edited by Jonathan Soldera

submission deadline 31 Jan 2026 | Viewed by 119 | Submission Open

Keywords: liver cirrhosis; hepatorenal syndrome; acute-on-chronic liver failure; liver transplan-tation; biomarkers; diagnostic imaging; artificial intelligence; inflammation media-tors; prognosis; end-stage liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Imaging in the Diagnosis and Management of Skin Diseases

edited by Lehang Guo

submission deadline 31 Jan 2026 | Viewed by 117 | Submission Open

Keywords: skin diseases; ultrasound imaging; optical coherence tomography (OCT) imaging; photoacoustic imaging; reflectance confocal microscopy (RCM) imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Predictive Biomarkers in Oncology

edited by

Jun Zhang

submission deadline 31 Jan 2026 | Viewed by 109 | Submission Open

Keywords: predictive biomarkers; precision oncology; liquid biopsy; treatment response; biomarker validation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Diagnosis and Management of Morbid Obesity

edited by Justyna Domienik-Karłowicz

submission deadline 31 Jan 2026 | Viewed by 105 | Submission Open

Keywords: morbid obesity; obesity diagnosis; body composition analysis; visceral adiposity; metabolic syndrome; biomarkers in obesity; genetic predisposition; comorbidity assessment; imaging techniques; risk stratification

(This special issue belongs to the Section Medical Imaging and Theranostics)

Role of Magnetic Resonance Imaging in Obesity and Diabetes: 2nd Edition

edited by

Per Lav Madsen

submission deadline 31 Jan 2026 | Viewed by 104 | Submission Open

Keywords: magnetic resonance imaging (MRI); obesity and diabetes; diabetic foot complications; brain atrophy; diabetic kidney disease (DKD); functional MRI; non-invasive imaging; early diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis, Management, and Prognosis of Liver Disease and Its Syndromes, Second Edition

edited by

Chien Hao Huang

submission deadline 31 Jan 2026 | Viewed by 97 | Submission Open

Keywords: acute liver disease; chronic liver disease; viral hepatitis; liver cirrhosis; non-alcoholic steatohepatitis (NASH); diagnosis; treatment; prognosis score

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Sports Injuries

edited by

Ki-Mo Jang

submission deadline 31 Jan 2026 | Viewed by 94 | Submission Open

Keywords: sports injury; sports medicine; diagnosis; treatment; surgery; rehabilitation

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Insights into the Diagnosis of Pediatric Cholestasis

edited by Paola Francalanci

submission deadline 31 Jan 2026 | Viewed by 94 | Submission Open

Keywords: extrahepatic cholestasis; intrahepatic cholestasis; biliary atresia; genetic liver disease; inborn errors of metabolism; jaundice; monogenic liver disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Lung Involvement in Connective Tissue Disease: Advances in Diagnosis and Management

edited by Laura Groșeanu

submission deadline 31 Jan 2026 | Viewed by 91 | Submission Open

Keywords: interstitial lung disease; connective tissue disease; complication; etiology; genetic risks; epigenetic changes; dysregulated immunity; CT patterns; mechanisms; screening; assessing; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis of Peripheral Vascular Diseases

edited by Micaela Iantorno

submission deadline 31 Jan 2026 | Viewed by 71 | Submission Open

Keywords: peripheral vascular disease; limb; CT angiography; MR angiography; ankle– brachial index; blood flow

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Trends in Ultrasound Imaging

edited by

Ştefan Cristian Vesa

and

Ingrid Andrada Vasilache

submission deadline 15 Feb 2026 | Viewed by 425 | Submission Open

Keywords: ultrasound; imaging; diagnostics; artificial intelligence; elastography; contrast-enhanced ultrasound; radiomics; 3D ultrasound; point-of-care ultrasound; interventional imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Acute Kidney Injury and Chronic Kidney Disease: From Pathogenesis to Diagnostics

edited by

Dimitris Kounatidis

and

Natalia G. Vallianou

submission deadline 28 Feb 2026 | 3 articles | Viewed by 12047 | Submission Open

Keywords: acute kidney injury (AKI); chronic kidney disease (CKD); pathogenesis; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Otolaryngology 2025

edited by

Rong-San Jiang

submission deadline 28 Feb 2026 | 4 articles | Viewed by 7961 | Submission Open

Keywords: ear; diagnosis; head and neck; management; nose; otolaryngology; throat

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis of Oral and Maxillofacial Disease: 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 28 Feb 2026 | 6 articles | Viewed by 7863 | Submission Open

Keywords: maxillofacial disease; oral disease; biomarkers; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Maternal–Fetal and Neonatal Diagnostics

edited by Elisa Bevilacqua

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7711 | Submission Open

Keywords: high risk pregnancy; twin pregnancy; maternal– fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnostic and Interventional Radiology

edited by

Serena Carriero

submission deadline 28 Feb 2026 | 6 articles | Viewed by 7377 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; image-guided therapy; AI; minimally invasive procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Colorectal Lesions

edited by Andrei Chitul

submission deadline 28 Feb 2026 | 4 articles | Viewed by 6847 | Submission Open

Keywords: colorectal lesions; diagnostic modalities; imaging techniques; machine learning; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Liquid Chromatography–Mass Spectrometry (LC-MS) in the Clinical Laboratory

edited by

Siddabasave Gowda B. Gowda

submission deadline 28 Feb 2026 | 5 articles | Viewed by 6828 | Submission Open

Keywords: LC-MS; clinical diagnostics; biomarker discovery; metabolomics; lipidomics; clinical samples; method validation; precision medicine; analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Contemporary Issues in Maternal-Fetal Medicine

edited by

Themistoklis Dagklis

and

Ioannis Tsakiridis

submission deadline 28 Feb 2026 | 5 articles | Viewed by 6551 | Submission Open

Keywords: obstetrics; high-risk pregnancy; maternal medicine; fetal medicine; prenatal diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Applications of Artificial Intelligence in Gastrointestinal Diseases

edited by Dimitra D. Dionysiou and Ioannis Gallos

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6263 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; biomarkers; screening/diagnosis; personalized medicine; treatment outcome; pathogenesis; risk management

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Computed Tomography Imaging in Medical Diagnosis, 2nd Edition

edited by

Fabio Sandomenico

submission deadline 28 Feb 2026 | 4 articles | Viewed by 5178 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

Technological Advances in Oral and Maxillofacial Surgery for Diagnosis

edited by

Maria Giulia Cristofaro

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4675 | Submission Open

Keywords: oral and maxillofacial surgery; oral cancers; maxillofacial trauma; surgical and informatics technology; intraoperative navigation; robotic surgery; oral and maxillofacial surgery reconstruction; nanotechnologies; DNA sequencing

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Echocardiography, 2nd Edition

edited by

Giulia Elena Mandoli

submission deadline 28 Feb 2026 | 4 articles | Viewed by 4484 | Submission Open

Keywords: standard echocardiography; speckle tracking echocardiography; strain; myocardial deformation; 3D echocardiography; valvular reconstruction; differential diagnosis; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI in Dermatology

edited by Jonathan Shapiro

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4243 | Submission Open

Keywords: teledermatology; artificial intelligence; AI algorithms; natural language processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Gynecological Oncology: Advanced Diagnosis and Management in 2025

edited by

Zoard T. Krasznai

and

Rudolf Lampé

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4014 | Submission Open

Keywords: gynecology; oncology; endometrial cancer; ovarian cancer; cervical cancer; diagnosis; staging; surgical methods; standardization of surgery; treatment; innovation; precision medicine; artificial intelligence; machine learning

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Management in Anesthesia and Pain Medicine

edited by Jamal Hasoon

submission deadline 28 Feb 2026 | 4 articles | Viewed by 3794 | Submission Open

Keywords: anesthesia and pain medicine; interventional pain management; regional anesthesia; neuromodulation; treatment outcomes; clinical practice patterns; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in the Diagnosis and Management of Liver Disease and Liver Transplantation

edited by Ioana Gabriela Lupescu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3665 | Submission Open

Keywords: focal and diffuse liver pathology; liver transplantation; MPMRI; MDCT; advanced imaging techniques; specific liver contrast material; imaging biomarkers; interventional radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Perspectives and Gaps in the Diagnosis and Management of Rheumatic Diseases

edited by Vikas Majithia

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3660 | Submission Open

Keywords: rheumatology; rheumatic diseases; inflammatory connective tissue diseases; rheumatoid arthritis; systemic lupus erythematosus; vasculitis; spondyloarthritis; scleroderma; osteoarthritis; current perspective; diagnosis; treatment; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances and Approaches in Managing Neurological Disorders: Multi-Omics and P4 Medicine

edited by

Shashanka Ashili

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3621 | Submission Open

Keywords: multi-omics; neurological disorders; P4 medicine; Appomics; neurodegenerative disorders; neurodevelopmental disorders; personalized medicine; bioinformatics; aging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnosis and Management in Pediatric Surgery

edited by Ioannis A. Valioulis

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3536 | Submission Open

Keywords: pediatric surgery; neonatal surgery; pediatric urology; pediatric oncology; laparoscopy in children; robotic surgery for children; organ transplantation; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Molecular Pathology and Imaging for Precision Diagnosis and Treatment of Tumors

edited by

Maurizio Martini

submission deadline 28 Feb 2026 | 5 articles | Viewed by 3530 | Submission Open

Keywords: molecular pathology; molecular imaging; precision oncology; biomarkers; digital pathology; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3133 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Insights for Skin Melanoma

edited by

Luca Roncati

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2919 | Submission Open

Keywords: skin melanoma; tissue biopsy; histopathological examination; immunohistochemistry; dermatoscopy; reflectance confocal microscopy; modern artificial intelligence; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Thyroid Cancer: Types, Symptoms, Diagnosis and Management

edited by

Mara Carsote

, Mihai-Lucian Ciobica and

Claudiu Nistor

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2845 | Submission Open

Keywords: thyroid neoplasia; thyroiditis; imaging; functional imaging; thyroidectomy; tumor markers; histological exam; molecular findings; pediatric population; pregnancy and thyroid conditions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2812 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Imaging in Bone and Soft-Tissue Sarcomas: Practice, Education, and Innovation—2nd Edition

edited by

Paolo Spinnato

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2321 | Submission Open

Keywords: soft-tissue sarcomas; bone sarcomas; imaging; MRI; CT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Alzheimer's Disease Diagnosis Based on Deep Learning

edited by Anees Abrol

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2316 | Submission Open

Keywords: Alzheimer's disease (AD); deep learning; MRI; demographic information; disease probability map; convolutional neural network (CNN)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Next-Generation Diagnostic Strategies: Bridging Health Sciences and Laboratory Medicine

edited by

Syed M. Shahid

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2281 | Submission Open

Keywords: diabetes mellitus; clinical diagnostics; biomarkers; prevision medicine; glycemic control; digital health

(This special issue belongs to the Section Clinical Laboratory Medicine)

Innovative Diagnostic Approaches in Retinal Diseases

edited by

Benedetto Falsini

and Andrea Cusumano

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2126 | Submission Open

Keywords: retinal diseases; electrophysiology; imaging; optical coherence tomography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis, Treatment, and Management of Hair Disorders

edited by Neil Jairath and

Vignesh Ramachandran

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2000 | Submission Open

Keywords: hair loss; alopecia; management; cicatricial; diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Microwave Radiometry for R&D and Practical Applications in 2025

edited by

Igor Goryanin

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1706 | Submission Open

Keywords: microwave radiometry; core body temperature; breast cancer detection; artificial intelligence; COVID-19 pneumonia; vulnerable plaque; carotid; hypothermia; hyperthermia; ischemic stroke; traumatic brain injury; rheumatoid arthritis; diabetic foot; brown adipose tissue activity; vesicoureteral reflux

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Application of Neural Networks in Medical Diagnosis

edited by

Hamid Reza Marateb

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1572 | Submission Open

Keywords: neural networks in diagnostics; medical imaging analysis; deep learning in healthcare; predictive modeling for disease detection; clinical decision support systems; interpretability and explainability in AI; biomedical data processing; personalized medicine applications

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Trends in Cardiovascular Imaging: 2nd Edition

edited by

Hans-Christoph Becker

submission deadline 28 Feb 2026 | 3 articles | Viewed by 1533 | Submission Open

Keywords: cardiac CT; cardiac MRI; hybrid and multimodality imaging; artificial intelligence and machine learning; coronary artery disease; myocardial tissue characterization; congenital heart disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Endocrinology Pathology

edited by

Mara Carsote

Ana Valea

and

Claudiu Nistor

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1532 | Submission Open

Keywords: histological classification and reporting; cytological analysis; fine-needle aspiration; molecular markers; immunohistochemistry; hormone; dynamic hormonal testing; endocrine tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis and Management of Skin Diseases

edited by

Montserrat Fernández-Guarino

submission deadline 28 Feb 2026 | 3 articles | Viewed by 1467 | Submission Open

Keywords: dermatology; skin disease; molecular diagnostics; laboratory test; assessment of therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Subjective Experiences of Decline and Dementia Risk: Cognitive, Functional, and Emotional Predictors of Cognitive Decline

edited by Katya Numbers

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1293 | Submission Open

Keywords: subjective cognitive decline (SCD); dementia risk; cognitive complaints; functional decline; emotional well-being; early diagnosis and intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ultrasound Elastography in Musculoskeletal Disorders: From Bench to Bedside

edited by Yoshiki Yamakoshi

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1263 | Submission Open

Keywords: ultrasound elastography; shear wave elastography; musculoskeletal ultrasound; tissue elasticity; tendon and ligament imaging; myofascial pain syndrome; sports medicine; rehabilitation; diagnostic imaging; muscle stiffness

(This special issue belongs to the Section Medical Imaging and Theranostics)

Displaying special issue 251-300 on page 6 of 14.

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