Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.9
3.3
Journals
Diagnostics
Special Issues
Recent Advances in Clinical Biochemistry, 2nd Edition
share announcement

Recent Advances in Clinical Biochemistry, 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Laboratory Medicine".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 845

Special Issue Editor

Dr. Yu Chen

E-Mail Website
Guest Editor
1. Horizon Health Network, 180 Woodbridge Street, Fredericton, NB, Canada
2. Department of Pathology, Dalhousie University, 6299 South St, Halifax, NS, Canada
3. Discipline of Laboratory Medicine, Memorial University of Newfoundland, St. John's, NL, Canada
Interests: medical biochemistry; clinical toxicology; biomarkers; laboratory test utilization; evidence-based medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue titled "Recent Advances in Clinical Biochemistry, 2nd Edition” features a compilation of groundbreaking research and updates in the field of clinical biochemistry, highlighting pioneering research and advancements specifically in the diagnostic arena. It explores the development of novel biomarkers and biotechnological innovations that facilitate the early and accurate detection of diseases. The issue covers the latest techniques in proteomic and metabolomic profiling, which are pivotal in identifying disease-specific patterns. It also examines the integration of high-throughput technologies, including next-generation sequencing and mass spectrometry, in clinical diagnostics. Furthermore, the role of artificial intelligence and machine learning in interpreting complex biochemical data is discussed. This Special Issue underscores the importance of clinical biochemistry in advancing medical diagnosis through innovative and robust methodologies. In addition, this Special Issue will address challenges and opportunities to optimize diagnostic stewardship efforts in all areas of the medical laboratory.

Dr. Yu Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical biochemistry
  • medical diagnosis
  • biomarkers
  • proteomic profiling
  • metabolomic profiling
  • high throughput technologies

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

23 pages, 1166 KB  
Review
Recent Trend of Laboratory Tests in Common Gastrointestinal Tract Disorders
by Terence A. Agbor and Waliul I. Khan
Diagnostics 2025, 15(23), 2998; https://doi.org/10.3390/diagnostics15232998 - 26 Nov 2025
Viewed by 655
Abstract
The gastrointestinal (GI) tract is a complex organ system affected by multiple disorders with diverse etiologies ranging from infections to immune dysfunction disorders and cancers. Various GI disorders, such as Helicobacter pylori infection, inflammatory bowel disease (IBD), celiac disease, irritable bowel syndrome (IBS), [...] Read more.
The gastrointestinal (GI) tract is a complex organ system affected by multiple disorders with diverse etiologies ranging from infections to immune dysfunction disorders and cancers. Various GI disorders, such as Helicobacter pylori infection, inflammatory bowel disease (IBD), celiac disease, irritable bowel syndrome (IBS), and colon cancer, are common and cause significant morbidity, mortality, and healthcare costs. These disorders present with overlapping signs and symptoms, warranting the need for accurate laboratory diagnostic tests for appropriate treatment implementation and treatment monitoring. The gold standard confirmatory diagnostic test for most GI disorders is endoscopy and biopsy for histological analysis. Biomarkers in blood and stool are also routinely used either as first-line screening tests or for treatment monitoring in many GI disorders. This review summarizes common GI disorders along with related currently used clinical laboratory tests in screening, diagnosis, and monitoring of these diseases, outlining the methodology, utilization, advantages, and limitations of these tests. We also highlight the effectiveness of each test as well as the professional recommendations and clinical guidelines for their use where available. Finally, we shed some light on potential future tests and biomarkers that aid in diagnosing GI disorders and how these biomarkers can be used in conjunction to complement the current tests. Some of the potential future biomarkers discussed include the differential expression of gut microbiota and their respective metabolites, as well as cytokines, as potential tests that can be used to diagnose diseases, distinguish between disease subtypes, predict disease severity and occurrence, and optimize treatment decisions. Comprehending the effectiveness of various methodologies for laboratory diagnosis of GI disorders is crucial for health care personnel, including clinical laboratory professionals and clinicians, regarding testing options, test utilization, and interpretations of results. Insights into future tests in GI diseases in the context of microbiomes, metabolites, and immune mediators based on advanced technology are also important in their appropriate clinical utilization. Full article
(This article belongs to the Special Issue Recent Advances in Clinical Biochemistry, 2nd Edition)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop